Volume 13 (2026) - Issue 5, May
Review Articles
PHLORIZIN: A COMPREHENSIVE REVIEW OF ITS PHARMACOLOGY, MECHANISMS, AND THERAPEUTIC POTENTIAL
A naturally occurring dihydrochalcone glycoside, Phlorizin, is mostly found in apple tree species and other Rosaceae family members. Its diverse range of biological actions, including antidiabetic, antioxidant, anti-inflammatory, cardioprotective, nephroprotective, neuroprotective, and anti-obesity properties, has garnered significant scientific attention. The creation of contemporary SGLT2 inhibi...
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BIOMECHANICAL ALTERATIONS IN WOMEN WITH POLYCYSTIC OVARY SYNDROME: LINKING LUMBOPELVIC ALIGNMENT
Polycystic ovary syndrome (PCOS) is a complex endocrine characterized by hyperandrogenism, hormonal imbalances, and metabolic disruptions, leading to reproductive complications and increased risk of cardiometabolic diseases. While lifestyle modifications are the cornerstone of PCOS management, pharmacological interventions, including metformin, oral contraceptives, and anti-androgens, are commonly...
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NANOBOTS AND SMART DRUG DELIVERY: BRIDGING THE GAP BETWEEN NANOTECHNOLOGY AND MEDICINES
Nanobots and smart drug delivery system is one of the radical convergences of nanotechnology and mainstream medicine with unprecedented precision, efficiency and control in therapeutic intervention. Conventional methods of delivering drugs are usually limited by low bioavailability, non-selective distribution, systemic toxicity and variable drug levels that can result in a low level of efficacy an...
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THERAPEUTIC POTENTIAL OF MEDICINAL PLANTS FROM ANDHRA PRADESH
Andhra Pradesh possesses remarkable floristic diversity due to its varied geography, climate, coastal plains, Eastern Ghats, and dry deciduous forest regions. For generations, tribal groups and rural communities in the state have relied on ethnomedicinal plants as an important source of primary healthcare. This study presents a comprehensive account of 59 ethnomedicinal plant species belonging to ...
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BIODIESEL FROM NATURAL RESOURCES: A COMPREHENSIVE REVIEW OF FEEDSTOCK PRODUCTION AND SUSTAINABILITY
Biodiesel is a non-toxic and renewable source based on, mainly, petroleum-derived products which are often produced from domestic natural sources like soybean, rapeseed, and coconuts, and also derived from cooking oils that are recycled for natural use. Vegetable oils gave the idea of substituting fuels for diesel engines. But due to their characteristics of low cold flow, low volatilities, and in...
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INNOVATIONS IN LIPOSOMAL DRUG DELIVERY: A COMPREHENSIVE REVIEW OF STRUCTURE, PREPARATION, APPLICATIONS, AND THERAPEUTIC POTENTIAL
Liposomes are spherical vesicles with one or more concentric peel of phospholipid bilayers enclosing an aqueous core. Liposomes, which can be nontoxic or biodegradable, are a strong delivery system of tranches of drugs. Liposomes (or lipid vesicles) are a type of platform with different applications, for example as carriers that take drugs or other macromolecules into the bodies of humans and anim...
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Research Articles
PHENOLIC-RICH EXTRACT OF CURCUMA LONGA L. MITIGATES ETHANOL-INDUCED GASTRIC TOXICITY VIA ANTIOXIDANT DEFENSE RESTORATION
Excessive alcohol consumption is a major cause of gastric mucosal injury, primarily mediated by oxidative stress, inflammation, and disruption of gastric acid balance. Although proton pump inhibitors and H2-receptor antagonists are standard treatments, their long-term use is associated with adverse effects and high costs, necessitating safer and more affordable alternatives. Curcuma longa, a medic...
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PHYTOCHEMICAL STUDIES AND EVALUATION OF THE ANTIOXIDANT AND ANTIDIABETIC ACTIVITIES OF TERMINALIA CATAPPA L. (COMBRETACEAE) AND SENNA OCCIDENTALIS (L.) LINK (FABACEAE) FROM IVORY COAST
Diabetes mellitus is a major public health challenge worldwide, particularly in sub-Saharan Africa where conventional therapeutic resources remain limited. In Ivory coast, the use of medicinal plants in the management of diabetes remains widespread despite advances in modern medicine. This study aims to evaluate the antidiabetic potential of two Ivorian medicinal plants, Terminalia catappa L. (Com...
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IN-VITRO ANTIPLASMODIUM ACTIVITY OF DIFFERENT EXTRACTS BAUHINIA VARIEGATA
Malaria remains a major global health concern due to increasing resistance of Plasmodium falciparum to existing antimalarial drugs. The present study evaluates the in-vitro anti-plasmodial activity and cytotoxicity of methanolic and aqueous leaf extracts of Bauhinia variegata. Extracts were prepared using Soxhlet and maceration methods and subjected to phytochemical screening. Anti-plasmodial acti...
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DESIGN, SYNTHESIS, AND PHARMACOLOGICAL ASSESSMENT OF NEW BENZOXAZOLE-BASED COMPOUNDS
A series of novel benzoxazole derivatives (4a–4i) were designed, synthesized, and evaluated for their in-vitro antifungal activity against seven phytopathogenic fungi, including G. saubinetii, T. cucumeris, S. sclerotiorum, V. dahliae, F. oxysporum, P. capsici and F. proliferatum, using the mycelial growth inhibition method. All compounds were initially screened at 100 mg/L, and active compounds...
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EXTRACTION AND COMPREHENSIVE PHYTOCHEMICAL PROFILING OF PEDALIUM MUREX
Medicinal plants are an invaluable source of bioactive compounds with therapeutic potential. Pedalium murex, commonly known as “Gokhru,” has been traditionally used in Ayurveda for managing urological disorders, reproductive health, and inflammatory conditions. This study aimed to perform a comprehensive phytochemical investigation, extraction, and quantification of bioactive constituents in t...
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PHARMACOGNOSTIC CHARACTERIZATION, PHYSICOCHEMICAL STANDARDIZATION, AND PHYTOCHEMICAL PROFILING OF THE WHOLE PLANT OF ORTHOSIPHON THYMIFLORUS (ROTH) SLEESEN (LAMIACEAE)
Orthosiphon thymiflorus (Roth) Sleesen (Lamiaceae), locally known as "Kattuthritha" or "Neer-naadan," is a perennial herb valued in South Indian and Southeast Asian traditional medicine for its diuretic, anti-inflammatory, and anti-diabetic properties. Despite its ethnopharmacological relevance, comprehensive pharmacognostic standards for this species are lacking, hindering quality control and aut...
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STANDARDIZATION OF SARAL VIRECHAN CHURNA AND SWADISTHA VIRECHAN CHURNA
Saral virechan churna and Swadishtha virechan churna are polyherbal formulation primarily used in constipation. Saral virechan contains liquorice, fennel, himaj, pepper, ginger, sindhavmithu, sakar and suddha sulphur, while Swadishtha virechan contains liquorice, fennel, senna, sakar and suddha sulphur. The present study was carried out to establish quality parameters of Saral virechan and Swadist...
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PHYTOCHEMICAL AND PHARMACOGNOSTIC EVALUATION OF UNEXPLORED MEDICINAL PLANTS
The growing costs to society and the economy of neurodegenerative illnesses like Parkinson's and Alzheimer's, as well as the hunt for natural compounds with neuroprotective properties. Guapira costaricana and Quercus laurifolia have a long history of medicinal usage. Numerous polyphenols and flavonoid chemicals found in Quercus laurifolia have been studied in depth for their anti-inflammatory and ...
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FORMULATION AND EVALUATION OF HERBAL MOSQUITO REPELLENT CREAM
Herbal mosquito repellents are natural products designed to repel mosquitoes and other biting insects. They are made from plant-based ingredients, including essential oils, herbs, and other botanical extracts. Mosquito-borne diseases, including malaria, dengue, and Zika, constitute a formidable global health challenge, resulting in approximately 750,000 fatalities annually. This study aims to addr...
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