7.
Excessive alcohol consumption is a major cause of gastric mucosal injury, primarily mediated by oxidative stress, inflammation, and disruption of gastric acid balance. Although proton pump inhibitors and H2-receptor antagonists are standard treatments, their long-term use is associated with adverse effects and high costs, necessitating safer and more affordable alternatives. Curcuma longa, a medic...
Elijah Oladapo Oyinloye *, Abdullahi Akanji Murtala, Farouk Adedeji Oladoja, Victor Emmanuel Okonkwo and Qudus Babajide Adeneye
Department of Pharmacology and Toxicology, Faculty of Pharmacy, Olabisi Onabanjo University, Sagamu Campus, Ogun State, Nigeria.
DOI: 10.13040/IJPSR.0975-8232.IJP.13(5).436-44
436-444
8.
Diabetes mellitus is a major public health challenge worldwide, particularly in sub-Saharan Africa where conventional therapeutic resources remain limited. In Ivory coast, the use of medicinal plants in the management of diabetes remains widespread despite advances in modern medicine. This study aims to evaluate the antidiabetic potential of two Ivorian medicinal plants, Terminalia catappa L. (Com...
Koidio Bindé Boris *, Kadja Amani, Mamyrbekova-Békro Janat Akhanovna and Bekro Yves-Alain
Laboratoire de Chimie Bio-Organique et de Substances Naturelles (LCBOSN), UFRSFA, Université Nangui ABROGOUA, 02 BP 801 Abidjan 02, Ivory Coast.
DOI: 10.13040/IJPSR.0975-8232.IJP.13(5).445-58
445-458
9.
Malaria remains a major global health concern due to increasing resistance of Plasmodium falciparum to existing antimalarial drugs. The present study evaluates the in-vitro anti-plasmodial activity and cytotoxicity of methanolic and aqueous leaf extracts of Bauhinia variegata. Extracts were prepared using Soxhlet and maceration methods and subjected to phytochemical screening. Anti-plasmodial acti...
Vikash Jha *, Raman Shivhare, Yogendra Singh and Sunil Singh
Shri Ramnath Singh Mahavidyalaya (Pharmacy), Gormi, Bhind, Madhya Pradesh, India.
DOI: 10.13040/IJPSR.0975-8232.IJP.13(5).459-63
459-463
10.
A series of novel benzoxazole derivatives (4a–4i) were designed, synthesized, and evaluated for their in-vitro antifungal activity against seven phytopathogenic fungi, including G. saubinetii, T. cucumeris, S. sclerotiorum, V. dahliae, F. oxysporum, P. capsici and F. proliferatum, using the mycelial growth inhibition method. All compounds were initially screened at 100 mg/L, and active compounds...
Amreesh Singh *, Yogendra Singh and Saurabh Jain
Shri Ramnath Singh Mahavidyalaya (Pharmacy), Gormi, Bhind, Madhya Pradesh, India.
DOI: 10.13040/IJPSR.0975-8232.IJP.13(5).464-69
464-469
11.
Medicinal plants are an invaluable source of bioactive compounds with therapeutic potential. Pedalium murex, commonly known as “Gokhru,” has been traditionally used in Ayurveda for managing urological disorders, reproductive health, and inflammatory conditions. This study aimed to perform a comprehensive phytochemical investigation, extraction, and quantification of bioactive constituents in t...
Balbir Singh *, Pankaj Mishra and Pushpendra Kannojia
BIU College of Pharmacy, Bareilly International University, Bareilly, Uttar Pradesh, India.
DOI: 10.13040/IJPSR.0975-8232.IJP.13(5).470-77
470-477