REPURPOSING AND PHYTOCHEMICAL INVESTIGATION OF SALACIA OBLONGA ROOT EXTRACT RESPONSIBLE ANTICANCER ACTIVITY AGAINST BREAST CANCER CELL LINE (MCF-7)
Salacia oblonga wall, a native shrub, also known as Saptrangi and Ponkoranti, belongs to the family Celastraceae, is distributed across the world. A large number of chemical constituents such as salacinol, kotalanol, neokotalanol, neosalacinol, and mangiferin are isolated from S. oblonga, which show various pharmacological activities. Salacia oblonga wall is being used in several herbal preparatio...
Medicinal plant is the basic and most significant part of the traditional medicinal system. The different plant contains medicinal properties, also known as an herbal plant. Bombax ceiba L plant of Bombacaceae family shows many Pharmacological activities. It is also called as Kate Savar and Semal. It is a native plant of western Africa. It is naturally obtained in Pakistan, India, and Myanmar. Bom...
NEUROPROTECTIVE ACTIVITY OF ASCOPHYLLUM NODOSUM ON EXPERIMENTLLY INDUCED GLOBAL CEREBRAL ISCHEMIA/REPERFUSION INJURY IN MICE
Background: Ascophyllum nodosum has been used in oriental medicine to treat a variety of remedies, including some neurological disorders. Ascophyllum nodosum rich in phenolic antioxidant (rich in polyphenol) have been identified as major active component exhibiting antioxidant, anti-inflammatory and neuroprotective effects. The present study is to evaluate the neuroprotective effect of Ascophyllum...
The aim of the present study is the phytochemical screening of gum of Curcuma amada (Mango ginger). Natural gums are economic, easily available and found useful as a tablet binder. The phytochemical properties of a gum obtained from the rhizomes of Curcuma amada were characterized by various test including a test for steroids, tannins, flavonoids, amino acids, carbohydrates, and glycosides. All of...
New series of N-(3-chloro-2-oxo-4-substituted-azetidine-1-yl) 2-methyl-1H-indole-3-carboxamide derivatives (VIa-d) were prepared and tested for their antibacterial and antifungal activity. The synthesis is based on the condensation of phenylhydrazine and ethyl acetoacetate in the presence of acetic acid to ethyl (2-methyl-1H- indol-3-yl)-2-oxoacetate (III) which on reaction with hydrazine hydrate ...
Standardization is the need of the hour in Ayurvedic system of medicine. The traditional systems of medicine are really effective but the problem with them is they lack in quality assurance. This enables us to recognise the quality of the formulation. The Central Council of Research in Ayurveda and Siddha has prescribed the preliminary guidelines for testing the quality of these formulations. It i...
APPLICATION OF MOLECULAR BEACON BASED BIOSENSOR AGAINST rs699 SNP IN HYPERTENSIVE AND NON- HYPERTENSIVE PUNJABI POPULATION
Molecular beacons have shown their topnotch potential in a variety of basic research, biomedical detection and clinical diagnosis. Their excellent selectivity, sensitivity, detection without separation have made them widely accepted tool for nucleic acid analysis. MBs present high-throughput screening of SNPs. The use of SNPs in the detection of genetic disorders is facilitated by the recent dis...
Moringa oleifera, an important medicinal plant is one of the most widely cultivated species of the family Moringaceae. It is highly valued from time immemorial because of its vast medicinal properties. The present article provides all necessary information regarding its phytochemical investigations, morphological studies and medicinal properties like anaemia, anxiety, asthma, blackheads, blood imp...
An intensive phytochemical study of the two parts of the Piper caldense plant brings the isolation of secondary metabolites, generated by shikimate and the mevalonate pathways. Using chromatographic techniques, the ethanolic extract of leaves afforded two pheophytyns, the pheophytin (1), 151-hydroxy-pophyrinlactone a (2), a mixture of the β-sitosterol and stigmasterol steroids (3-4). Four derivat...
Aim of study: Compare the study on physio-chemical parameters of Acacia arabica and Prosopis juliflora. Material and Methods: The ethanolic extract of on Acacia arabica and Prosopis juliflora were using physio-chemical parameters and preliminary phytochemical investigation. Results and Discussion: In this study. I have done the comparative pharmacognostic study on Acacia arabia and Prosopis julifl...