Cocoa and chocolate can also be rich sources of flavonoids. Flavanols isolated from cocoa exhibit strong antioxidant properties in-vitro. Flavanol-rich cocoa and chocolate increased plasma antioxidant capacity and reduced platelet reactivity. Flavonoids are phenolic substances isolated from a wide range of vascular plants, almost over 8000 individual compounds known. They act in plants as antioxid...
In the present study, an indigenous herbal formulation containing the ethanolic extracts of rhizomes of Curcuma longa, fruits of Terminalia chebula, leaves of Azadirachta indica, leaves of Lawsonia inermis and leaves of Achyranthus asperus were prepared and studied for its wound healing activity in an ointment base by using in in-vivo excision wound model in albino wistar rats. The ointment was pr...
Antioxidants play an essential role in the inhibition of the oxidative damage of the biomolecules. Flavonoids are known as potent antioxidants and are present in abundance in many of the fruits and vegetables besides being present in a large number of medicinal botanicals. A quantitative analysis of the antioxidant activity of quercetin, luteolin, kaempherol and taxifolin belonging to the flavon...
The genus Tribulus belongs to family Zygophyllaceae comprises approximately 25 species which grow as prostrate hairy herbs in tropical and warm regions. In this review, the literature data on phytochemical investigations of the Tribulus terrestris are compiled. The well-recognized groups of secondary metabolites were sterols, alkaloids, flavonoids, and steroidal saponins....
People, who have visits to high altitudes, do experience a certain type of health problems as they transit to different altitude ranges. With ascend to high altitude, various kinds of acute and chronic physiological changes occur which influence all system of the human body. These problems although have temporary manifestations, arising due to maladjustment of the body to abrupt altitudinal change...
EVALUATION OF ANTIOXIDANT, ANTI-INFLAMMATION AND CHEMICAL COMPOSITION OF METHANOLIC EXTRACT OF AMOMUM MASTICATORIUM THWAITES (ZINGIBERACEAE)
The anti-inflammatory and antioxidant activities of the methanol extract of Amomum masticatorium rhizome were observed in various experimental models. Phytochemical constituents like phenols and flavonoids were also estimated. The antioxidant activity was evaluated by DPPH and superoxide radical scavenging assays. The extract showed significant antioxidant activity. The in-vitro anti-inflammatory ...
GC-MS ANALYSIS OF THE METHYLENE CHLORIDE AND n-BUTANOL FRACTIONS OF THE METHANOLIC EXTRACT OF ANTIGONON LEPTOPUS (HOOK & ARN.)
Antigonon leptopus Hook & Arn. (family Polygonaceae), also called: chain of love, Queen’s wreath and Mexican creeper is a fast-growing vine with stems reaching up to 20 feet long. It has heart-shaped, green leaves climbing by tendrils which wrap around many types of supports. It is native to Mexico and commonly found in tropical Asia, Africa, the Caribbean, and the Americas. It possesses ant...
PHARMACOGNOSTICAL AND PHYTOCHEMICAL EVALUATION OF TRICHOSANTHES CUCUMERINA VAR. CUCUMERINA LINN. LEAVES
Trichosanthes cucumerina var. cucumerina Linn. is an annual monoecious climber. Trichosanthes cucumerina var. cucumerina Linn. mainly distributed in Asian countries like India, Sri Lanka, Bangladesh, Burma, Malaysia, and Australia. Trichosanthes cucumerina var. cucumerina is a wild variant (Cucurbitaceae) the major active components are triterpenoids, saponins, and cucurbitacins; chemical consti...
A COMPARATIVE PHYTOCHEMICAL APPROACH FOR SUBSTITUTION OF STEM BARK WITH SMALL BRANCHES IN BUCHANANIA LANZAN FOR MEDICINAL USE
Overexploitation of many traditional medicinal plants like Buchanania lanzan Spreng. has become a threat and shortly, many medicinal plants may be unavailable for use in the medicinal industry. The present study outlines the concept of plant part substitution. Stem bark and small branches of B. lanzan are compared based on physicochemical analysis, phytochemical analysis, total phenolic content, t...
EVALUATION OF THE IMMUNOMODULATORY EFFECT OF PIPLARTINE AND ITS DERIVATIVE ON PERITONEAL MACROPHAGES OF SWISS MICE INFECTED WITH LEISHMANIA AMAZONENSIS
Piplartine is an amide obtained from Piper tuberculatum, which is promising in antiparasitic tests. Therefore, it has been used as the basis for the synthesis of new molecules. This study was designed to analyze the immunomodulatory effect of piplartine (A) and its derivative (B), in-vitro, on macrophages infected with Leihmania amazonensis, as well as the production of hydrogen peroxide (H2O2), n...