The leaf galls of Mangifera indica L. are very characteristic and possess medicinal properties, due to their phytochemical profile. Hence, a pharmacognostic and phytochemical study was carried out. The microscopic evaluation of leaf gall powder of Mangifera indica revealed the presence of calcium oxalate crystals, cork cells with resin and sclerites. The anatomy of mature galls exhibited character...
Aerva lanata has been used in traditional medicine for many years and used for the treatment of urinary bladder and kidney stones. The aim was to study the pharmacognostic characters and antimicrobial activity of important medicinal plant Aerva lanata (Amaranthaceae). The physicochemical, phytochemical and fluorescence analysis of powdered aerial and root parts of Aerva lanata was performed accord...
PROTECTIVE PROFILE OF CITRULLUS COLOCYNTHIS ROOT EXTRACTS ON LIPID PROFILE STATUS IN STZ CHALLENGED RATS
Diabetes mellitus is one of the widespread and severe metabolic disorders in humans all over the world. It is initially characterized by a loss of glucose homeostasis resulting from defects in insulin secretion, insulin action or both resulting in impaired glucose metabolism and other energy-yielding fuels such as lipids and proteins. The association of hyperglycemia with altered lipid parameters ...
This study was aimed to maximize the benefits of the use of by-products (oil cake) of olive fruits and black seeds after extraction of their fixed oils, rather than their use as animals feed or landfilling or composting. The cake of both seeds was assessed by HPLC for their main bioactive marker compounds (thymoquinone for black seed and oleuropein for olive fruit), to choose the best method for e...
The influence of roots and leaf extracts of Jasminum grandiflorum was studied for its wound healing activity using the excision wound model. The roots and leaves of Jasminum grandiflorum were extracted with alcohol 90%, were subjected to phytochemical investigation. The root and leaf extracts were screened for wound healing activity. The animals were divided into four groups in excision wound mode...
EXTRACTION, PURIFICATION AND DETERMINATION OF PHYTO-COMPONENT OF FATTY ACIDS FROM IRVINGIA GABONENSIS SEEDS
Objective: This study was designed to extract, purify and determine the phyto-components in the petroleum ether extract of Irvingia gabonensis seeds (IGS). A multiple batch extraction procedure was employed using petroleum ether as a solvent. A specified quantity of the IGS was size reduced, dispersed in freshly distilled water by heating to a temperature of 80 ºC. The dispersion was then filtere...
EVALUATION OF ANTIMICROBIAL ACTIVITY OF THE STEM BARK OF MAESOBOTRYA DUSENII (PAX) HUTCHINSON (EUPHORBIACEAE)
Introduction: Infection due to antimicrobial resistance is currently one of the major threats to mankind. This study investigates the antimicrobial activity of the various extracts of the stem bark of Maesobotrya dusenii (Pax) Hutchinson (Euphorbiaceae). Methods: Pulverized 100 g of stem bark of M. dusenii extracted with methanol. Another 400 g of the plant material was also successively macerated...
Infectious diseases are one of the major problems in the world. After the discovery of penicillin, many classes of the antimicrobial agent were introduced and most infectious diseases were brought under control. However, the increased use of these antimicrobial agents in clinical practice was soon followed by the emergence of antibiotic resistance. Because of multiple drug resistance and adverse e...
Treatment based on traditional medicine is very popular in the developing world due to inexpensive properties. There is a growing interest in herbal medicine. Curcumin a hydrophobic poly-phenol is derived from turmeric, the rhizome of the herb Curcuma longa L. Neurodegenerative diseases have become a major challenge for public health because of their incurable status. Curcumin has an outstanding s...
SYNTHESIS, CHARACTERIZATION, ANTIOXIDANT AND ANTI-INFLAMMATORY ACTIVITY EVALUATION OF SOME SUBSTITUTED PYRAZOLE DERIVATIVES
A series of substituted acetophenones are condensed with hydrazides to the corresponding hydrazones which are subsequently cyclized by using volumizer-Haack reaction to give new pyrazole derivatives. All the compounds 4a, 4b, 4c, 4d, 4e were screened for antioxidant, anti-inflammatory activity. Few of the compounds showing good antioxidant and anti-inflammatory activity....