EVALUATION OF FICUS RACEMOSA LEAF FOR WOUND HEALING ACTIVITYAbstract
The wound healing activity of leaves of Ficus racemosa Linn. alcoholic, chloroform and ethyl acetate extract ointments were evaluated on Wistar rats by excision wound model for 12 days and incision wound model for 10 days. In incision model the parameter carried out was tensile strength of wounded skin. In excision model percentage wound contractions were determined for all the groups. Reference standard drug was curcumin ointment. Animals treated with extracts of Ficus racemosa Linn. showed a marked reduction in wound area in comparison to the control group from 4th day onwards. From the observations, it is found that in both the models, an alcoholic extract of Ficus racemosa and enriched diet had greater wound healing activity in terms of tensile strength in incision model and percentage wound closure, in excision model than that of other groups. Enriched diet also showed good wound healing activity which may be due to high protein content and fatty acids present in the oil.
A. Lavanya *, B. Madhava Reddy and V. Neeharika
Department of Phytochemistry and Pharmacognosy, G. Pullareddy College of Pharmacy, Mehdipatnam, Hyderabad, Telangana, India
28 October 2016
21 November 2016
26 December 2016
31 December 2016