SYNTHESIS, CHARACTERIZATION, ANTIOXIDANT AND ANTI-INFLAMMATORY ACTIVITY EVALUATION OF SOME SUBSTITUTED PYRAZOLE DERIVATIVESAbstract
A series of substituted acetophenones are condensed with hydrazides to the corresponding hydrazones which are subsequently cyclized by using volumizer-Haack reaction to give new pyrazole derivatives. All the compounds 4a, 4b, 4c, 4d, 4e were screened for antioxidant, anti-inflammatory activity. Few of the compounds showing good antioxidant and anti-inflammatory activity.
B. Lavanya, B. Nagasudha*, Y. Sivaram Reddy
Department of Chemistry, Creative Educational Society College of Pharmacy, Jawaharlal Nehru Technological University Anantapur, Kurnool, India
05 November 2013
21 January 2014
23 January 2014
01 February 2014