FORMULATION AND EVALUATION OF GEL CONTAINING MANGIFERA INDICA LEAVES EXTRACT FOR ANTI-BACTERIAL ACTIVITY
In the present study, an attempt was made to formulate ethosomal gel containing leaf extract of Mangifera indica, and was evaluated for antibacterial activity against gram-positive and gram-negative organisms. Different formulations of ethosomes using lecithin, cholesterol, and ethanol were prepared using Mangifera indica herbal leaf extracts. Carbopol 940 was used to prepare ethosomal gel. The en...
IDENTIFICATION OF BIOACTIVE COMPOUNDS OF ALCHEMILLA CAUCASICA USING GAS CHROMATOGRAPHY-MASS SPECTROMETRY
Alchemilla species (Rosaceae) are locally known as "aslanpençesi" in Turkey. Alchemilla plants (lady's mantle) are used in traditional medicine for different indications. In this study, the methanol extract of Alchemilla caucasica was analyzed using gas chromatography-Mass Spectrometry, while the mass spectra of the compounds found in the extract were matched with the National Institute of Standa...
PHARMACOGNOSTIC STUDY AND ANTIMALARIAL ACTIVITY OF THE METHANOL EXTRACT AND FRACTIONS OF BIXA ORELLANA L., (FAMILY BIXACAEA) LEAVES (ANNATTO PLANT) ON ALBINO MICE
The emergence of anti-malarial resistant parasites has posed a serious threat to the control and elimination of malaria. Therefore, there is a need for an alternative drug that is highly efficacious, affordable and safer for the treatment of malaria; hence, interest is now on the use of herbal medicine to treat malaria. Ogidi community in the Anambra State of Nigeria depends mainly on plants for t...
EFFECTS OF AQUEOUS METHANOLIC LEAF EXTRACTS OF INDIGENOUS PLANTS CLERODENDRUM COLEBROOKIANUM WALP AND CENTELLA ASIATICA LINN. ON CARBON TETRACHLORIDE INDUCED CARDIOTOXIC WISTER ALBINO RATS
Two indigenous plants Clerodendrum colebrookianum walp and Centella asiatica Linn. were selected to determine its cardioprotective activity on male Wister albino rats. Empirical research was designed to evaluate the cardioprotective activity of the leaves of both with special reference to its putative protective role. Aqueous methanolic extracts of both the plants were prepared by continuous hot p...
GASTRO-PROTECTIVE ACTIVITY OF THE LEAVES AQUEOUS EXTRACT OF DIOSPYROS MESPILIFORMIS ON GASTRIC ULCERS IN SWISS MICE
Information from ethnomedicine suggests that Diospyros mespiliformis possesses antiulcer properties. Thus, the purpose of this study was to evaluate its gastroprotective activity. The gastroprotective activity of the leaves aqueous extract of D. mespiliformis was evaluated by three experimental models of gastric ulcers in mice, namely: HCl/ethanol, HCl/ethanol with indomethacin pre-treatment and i...
Resveratrol (3, 5, 4′-trihydroxy stilbene) is a type of natural phenol, produced by several plants in response to injury or under attack by pathogens. These phytoalexin compounds are thought to have antioxidant, anticancer, and anti-inflammatory properties. Although resveratrol is commonly used as a dietary supplement, there is no conclusive evidence of whether or not resveratrol could be a viab...
The objective of this review is to update and assess the chemistry, composition, mechanism of action, pharmacokinetics, nutritional value and toxicology of garlic. The medicinal properties of garlic include immune functions, antibacterial activities, antifungal activities, antivirus activities, de-toxification, anti-oxidant agent, prevent platelet aggregation, reduction in blood pressure, loweri...
Curcuma amada and Curcuma aeruginosa are economically and medicinally very important species in India. Both of the species look similar in morphological nature. In the present study, an effort has been made to work out the identifying characters and detailed comparative account of both species for ready identification of the entire plant, live or in the herbarium and also the discrimination of dru...
In the present study, an attempt was made to evaluate the changes in testis protein and metabolic enzyme activities induced by epichlorohydrin (ECH), twenty-four albino male rats were divided randomly into four groups of six rats each. One group was left untreated as controls, and the other three groups were administered, respectively, for twelve consecutive weeks, (2) 50 mg of ECH /kg/b.wt, (3) 7...
Siddha system is one of the oldest and most ancient traditional prevailing medicinal systems in India especially in our south India. In our system, first preference is given for plant-based medicine. Plant-derived drugs have been a part of the evolution of human health care for thousands of years in India. Elathi kuligai is prepared as per classical Siddha textbook for the respiratory problem in t...