The plant of Desmodium triflorum Linn (Fabaceae) is reported to have great medicinal value. The aim of this study to evaluate pharmacognostic evaluation including examination of morphological characters, ash value, powder analysis, and extractive values was carried out. Phytochemical screening including chemical examination and chromatographic study were also carried out. This would help to scient...
About 4 extracts (hexane, acetone, ethanol, and methanol extraction) from the seeds of Centratherum anthelminticum was extracted. Gas Chromatography-Mass Spectroscopy characterized ethanol extract. Seven constituents from 9 peaks were identified. 2-Oxo-pentanoic acid and hexadecanoic acid are as the major constituents, and the minor constituents like Henicosanoic acid, 26-Phenoxy-hexacosanoic me...
ANTIHYPERLIPIDEMIC ACTIVITY OF ETHANOLIC EXTRACT OF AMORPHOPHALLUS PAEONIIFOLIUS TUBER IN TRITON WR 1339 INDUCED HYPERLIPIDEMIC RATS
Hyperlipidemia is the most prominent risk factor in coronary heart disease. The present study was designed to investigate the anti-hyperlipidemic activity of Amorphophallus paeoniifolius Tuber in Triton WR-1339 induced hyperlipidemic rats. Amorphophallus paeoniifolius extract was administered at a different dose of 250mg/kg, 500mg/kg (p.o) daily for 7 days to hyperlipidemic rats. Gemfibrozil is us...
Today, cancer can be considered as a serious threat to human health because its treatment is difficult and expensive. Also, genetic modifications are considered as risk factors for many diseases including cancer. To discover a benefit and promising therapeutic is one of the main goals research on cancer. Environmental and nutritional factors can affect the organism through genetic and epigenetic c...
FORMULATION AND EVALUATION OF GEL CONTAINING MANGIFERA INDICA LEAVES EXTRACT FOR ANTI-BACTERIAL ACTIVITY
In the present study, an attempt was made to formulate ethosomal gel containing leaf extract of Mangifera indica, and was evaluated for antibacterial activity against gram-positive and gram-negative organisms. Different formulations of ethosomes using lecithin, cholesterol, and ethanol were prepared using Mangifera indica herbal leaf extracts. Carbopol 940 was used to prepare ethosomal gel. The en...
IDENTIFICATION OF BIOACTIVE COMPOUNDS OF ALCHEMILLA CAUCASICA USING GAS CHROMATOGRAPHY-MASS SPECTROMETRY
Alchemilla species (Rosaceae) are locally known as "aslanpençesi" in Turkey. Alchemilla plants (lady's mantle) are used in traditional medicine for different indications. In this study, the methanol extract of Alchemilla caucasica was analyzed using gas chromatography-Mass Spectrometry, while the mass spectra of the compounds found in the extract were matched with the National Institute of Standa...
PHARMACOGNOSTIC STUDY AND ANTIMALARIAL ACTIVITY OF THE METHANOL EXTRACT AND FRACTIONS OF BIXA ORELLANA L., (FAMILY BIXACAEA) LEAVES (ANNATTO PLANT) ON ALBINO MICE
The emergence of anti-malarial resistant parasites has posed a serious threat to the control and elimination of malaria. Therefore, there is a need for an alternative drug that is highly efficacious, affordable and safer for the treatment of malaria; hence, interest is now on the use of herbal medicine to treat malaria. Ogidi community in the Anambra State of Nigeria depends mainly on plants for t...
EFFECTS OF AQUEOUS METHANOLIC LEAF EXTRACTS OF INDIGENOUS PLANTS CLERODENDRUM COLEBROOKIANUM WALP AND CENTELLA ASIATICA LINN. ON CARBON TETRACHLORIDE INDUCED CARDIOTOXIC WISTER ALBINO RATS
Two indigenous plants Clerodendrum colebrookianum walp and Centella asiatica Linn. were selected to determine its cardioprotective activity on male Wister albino rats. Empirical research was designed to evaluate the cardioprotective activity of the leaves of both with special reference to its putative protective role. Aqueous methanolic extracts of both the plants were prepared by continuous hot p...
GASTRO-PROTECTIVE ACTIVITY OF THE LEAVES AQUEOUS EXTRACT OF DIOSPYROS MESPILIFORMIS ON GASTRIC ULCERS IN SWISS MICE
Information from ethnomedicine suggests that Diospyros mespiliformis possesses antiulcer properties. Thus, the purpose of this study was to evaluate its gastroprotective activity. The gastroprotective activity of the leaves aqueous extract of D. mespiliformis was evaluated by three experimental models of gastric ulcers in mice, namely: HCl/ethanol, HCl/ethanol with indomethacin pre-treatment and i...
Resveratrol (3, 5, 4′-trihydroxy stilbene) is a type of natural phenol, produced by several plants in response to injury or under attack by pathogens. These phytoalexin compounds are thought to have antioxidant, anticancer, and anti-inflammatory properties. Although resveratrol is commonly used as a dietary supplement, there is no conclusive evidence of whether or not resveratrol could be a viab...