The genus Ruellia L. is sometimes called Dipteracanthus, it comprises about 150 species native to tropical and temperate North and South America. In this review, the literature data on phytochemical and biological investigations of the genus Ruellia are compiled. The well-recognized groups of secondary metabolites were flavonoids, lignans, coumarins, alkaloids, triterpenes, sterols, phenolic gly...
A rapid, simple, selective and precise UV-Visible spectrophotometric method has been developed for the determination of Curcumin in bulk and nano-formulation. The spectrophotometric detection was carried out at an absorption maximum of 421 nm using methanol as solvent. The method was validated for various validation parameters. The linearity range was found to be 5-25 μg/ml with a correlation coe...
The medicinal plants have attracted great attention in recent years for better therapeutic management of diseases. Nigella sativa is one of the most extensively studied plants and has gained more and more interest in potential medical use in recent years. Historical and traditional uses of this herb have been widely documented in ancient documents; and Nigella sativa has been broadly used througho...
Cancer is a disease of deregulated cellular behavior. Acquisition of oncogenic attributes, loss of tumor suppressive functions, evasion of physiological tissue architecture and interactions with the cellular microenvironment enable malignant cells to escape the mechanisms of normal cellular homeostasis in an organism. Cancer cells are therefore able to sustain unlimited proliferation, to thrive un...
CHEMICAL COMPOSITION AND ANTI-INFLAMMATORY ACTIVITY OF ESSENTIAL OILS FROM THE LEAVES OF OCIMUM BASILICUM L. AND OCIMUM GRATISSIMUM L. (LAMIACEAE)
Ocimum basilicum L. and Ocimum gratissimum L. (Lamiaceae) are widely distributed aromatic herbs used in ethnomedicinal management of a range of inflammatory disorders. In the present work, we evaluated the topical anti-inflammatory effects of the volatile constituents extracted from the fresh leaves of these plant species. Fresh leaves of the plants were subjected to hydro distillation to obtain t...
Turmeric (Curcuma longa) is a widely used popular Indian medicinal plant which belongs to the family of Zingiberaceae. Curcumin, an important constituent of turmeric, is known for various biological activities, primarily due to its antioxidant mechanism. Epidemiological observations are suggestive that turmeric consumption may reduce the risk of some form of cancers and render other protective bio...
ANTI-HYPERGLYCEMIC PLANTS USED BY THE TRADITIONAL HEALER OF WEST GODAVARI DISTRICT, ANDHRA PRADESH, INDIA
A survey was conducted to collect information about the effective medicinal plants used by the Traditional healer to treat diabetes. The use of herbal drugs increased worldwide because of the lack of side effects and efficacy. Traditional healing is practicing throughout the world to treat several diseases. Glycemic disease has become a severe issue in India and all over the world. The traditional...
ANTIOXIDANT ACTIVITY AND PHYTOCHEMICAL ANALYSIS OF FRACTIONATED LEAF EXTRACTS OF CATHARANTHUS ROSEUS
Antioxidant effectiveness of indigenous medicinal plant C. roseus leaves extracts and fractions with solvents of different polarity (ethanol, methanol, acetone, hexane, butanol, and water) were assessed for DPPH radical scavenging activity. The C. roseus extracts and fractions contained appreciable levels of the antioxidant activities of leaves of C. roseus at various concentrations. The leaves of...
Diabetes mellitus (DM), both insulin-dependent DM (IDDM) and non-insulin dependent DM (NIDDM) is a common and serious metabolic disorder throughout the world. Traditional plant treatments have been used throughout the world for the therapy of diabetes mellitus. Among many medications and other alternative medicines, several herbs have been known to cure and control diabetes; additionally, they hav...
ANTIDIABETIC POTENTIAL OF IVY GOURD (COCCINIA GRANDIS, FAMILY: CUCURBITACEAE) GROWN IN SRI LANKA: A REVIEW
Leaves of ivy gourd; Coccinia grandis (L.) Voigt (Family: Cucurbitaceae) is one of the well-known leafy vegetables, which has been consumed by Sri Lankans for centuries. The therapeutic potential of ivy gourd against diabetes is brought mainly by its antihyperglycemic, β-cell regenerative, antihyperlipidemic and antioxidant properties. Also, the optimum effective therapeutic dose of the aqueous C...