ANTIDIABETIC POTENTIAL OF IVY GOURD (COCCINIA GRANDIS, FAMILY: CUCURBITACEAE) GROWN IN SRI LANKA: A REVIEWAbstract
Leaves of ivy gourd; Coccinia grandis (L.) Voigt (Family: Cucurbitaceae) is one of the well-known leafy vegetables, which has been consumed by Sri Lankans for centuries. The therapeutic potential of ivy gourd against diabetes is brought mainly by its antihyperglycemic, β-cell regenerative, antihyperlipidemic and antioxidant properties. Also, the optimum effective therapeutic dose of the aqueous C. grandis extract was found to be safe in terms of hepatotoxicity, renotoxicity, hematotoxicity in-vivo. The scientific investigations confirmed the effectiveness of this leafy vegetable for the development of potential neutraceuticals against diabetes mellitus.
A. P. Attanayake * , K. A. P. W. Jayatilaka and L. K. B. Mudduwa
Department of Biochemistry, Faculty of Medicine, University of Ruhuna, Sri Lanka.
03 December 2016
18 January 2017
22 February 2017
01 March 2017