The influence of roots and leaf extracts of Jasminum grandiflorum was studied for its wound healing activity using the excision wound model. The roots and leaves of Jasminum grandiflorum were extracted with alcohol 90%, were subjected to phytochemical investigation. The root and leaf extracts were screened for wound healing activity. The animals were divided into four groups in excision wound mode...
EXTRACTION, PURIFICATION AND DETERMINATION OF PHYTO-COMPONENT OF FATTY ACIDS FROM IRVINGIA GABONENSIS SEEDS
Objective: This study was designed to extract, purify and determine the phyto-components in the petroleum ether extract of Irvingia gabonensis seeds (IGS). A multiple batch extraction procedure was employed using petroleum ether as a solvent. A specified quantity of the IGS was size reduced, dispersed in freshly distilled water by heating to a temperature of 80 ºC. The dispersion was then filtere...
EVALUATION OF ANTIMICROBIAL ACTIVITY OF THE STEM BARK OF MAESOBOTRYA DUSENII (PAX) HUTCHINSON (EUPHORBIACEAE)
Introduction: Infection due to antimicrobial resistance is currently one of the major threats to mankind. This study investigates the antimicrobial activity of the various extracts of the stem bark of Maesobotrya dusenii (Pax) Hutchinson (Euphorbiaceae). Methods: Pulverized 100 g of stem bark of M. dusenii extracted with methanol. Another 400 g of the plant material was also successively macerated...
Infectious diseases are one of the major problems in the world. After the discovery of penicillin, many classes of the antimicrobial agent were introduced and most infectious diseases were brought under control. However, the increased use of these antimicrobial agents in clinical practice was soon followed by the emergence of antibiotic resistance. Because of multiple drug resistance and adverse e...
Treatment based on traditional medicine is very popular in the developing world due to inexpensive properties. There is a growing interest in herbal medicine. Curcumin a hydrophobic poly-phenol is derived from turmeric, the rhizome of the herb Curcuma longa L. Neurodegenerative diseases have become a major challenge for public health because of their incurable status. Curcumin has an outstanding s...
SYNTHESIS, CHARACTERIZATION, ANTIOXIDANT AND ANTI-INFLAMMATORY ACTIVITY EVALUATION OF SOME SUBSTITUTED PYRAZOLE DERIVATIVES
A series of substituted acetophenones are condensed with hydrazides to the corresponding hydrazones which are subsequently cyclized by using volumizer-Haack reaction to give new pyrazole derivatives. All the compounds 4a, 4b, 4c, 4d, 4e were screened for antioxidant, anti-inflammatory activity. Few of the compounds showing good antioxidant and anti-inflammatory activity....
Hyperlipidaemia (Adhi dhoola noi) is a well known metabolic disorder, prevalent in 30-40% of the people worldwide. It is one of the most important factors of morbidity and mortality related to atherosclerotic cardiovascular disease and diabetes. Research articles prove hyperlipidaemia as an important factor that determines the risk of atherosclerotic heart disease and endocrinal disorders. Siddha ...
PHYTOCHEMICAL SCREENING ASSESSMENT, ANTIOXIDANT CAPACITY AND ANTIMICROBIAL SUSCEPTIBILITY OF EXTRACTS FROM CECROPIA PACHYSTACHYA TRÉCUL. CECROPIACEAE (URTICACEAE) AS SOURCE FOR HERBAL MEDICINES DEVELOPMENT
Several plants used for medicinal purposes can be found in the Brazilian Cerrado, among which highlights the genus Cecropia used as a bronchodilator, antitussive, anti-diabetic, anti-diarrheal, anti-hypertensive, anti-inflammatory and vasorelaxant. Between species, there is Cecropia pachystachya belongs to the Urticaceae family. This study aims to evaluate the phytochemical screening, antioxidant ...
BIOLOGICAL ACTIVITIES OF EXTRACTS AND SEASONAL VARIATION IN ESSENTIAL OIL COMPOSITION FROM MYRCIARIA GLAZIOVIANA (MYRTACEAE)
Extracts from leaves, stems and flower buds of Myrciaria glazioviana were analyzed for their antioxidant and anticholinesterase activity. The methanolic extracts showed the best results in reducing power (623.52 - 806.15 mg AA/g of extract), DPPH radical scavenging (IC50 = 9.77 - 14.06µg/mL) and lipid peroxidation inhibition activity (21.30 - 66.80 %). These data were correlated to the total phen...
Lantana indica Roxb. (Verbenaceae) is grown as an ornamental plant in tropical and subtropical regions of the world. The plant is used to treat asthma, abdominal disorders, bilious fever, cancer, catarrhal infections, chicken pox, eczema, hypertension, malaria, measles, swelling, rheumatism, tetanus, and ulcers. Phytochemical investigation of a methanolic extract of the leaves led to isolating thr...