IN-VITRO GERMINATION AND SOMATIC EMBRYOGENESIS VIA TISSUE CULTURE STUDIES OF TAVERNIERA CUNEIFOLIA (ROTH) ARN.
Taverniera cuneifolia (Roth) Arn. licorice of India comprises similar phytochemical constituents majorly the Glycyrrhizic acid (GA) that of plant Glycyrrhiza glabra L. but has been least studied in terms of their commercial applications. GA from the root extracts of T. cuneifolia exhibits promising anti-inflammatory, anti-tumor, and anti-germ tube formation protection and other cytotoxic activitie...
Kydia calycina, a member of the Malvaceae family known as Pulao, Boranga, or Pula, has been reported for its traditional uses as a medicinal plant. The presence of potentially active nutrients and their multifunctional properties make Kydia calycina leaves, root, bark, and stem perfect candidates for the production of phytopharmaceutical products. It is used traditionally as a remedy in differen...
ANTIOXIDANT POTENTIAL OF PUNICALAGIN IN AN IN-VITRO SYSTEM OF PRECISION CUT GOAT LIVER SLICES SUBJECTED TO OXIDATIVE STRESS
Oxidative stress has been implicated in various pathological diseases like neurodegenerative disorders, stroke, cancer, inflammation, atherosclerosis, etc., which upshots when the production of reactive oxygen species overwhelms the antioxidant defense mechanism. Nowadays, development of drugs with antioxidant potential gained utmost importance therapeutically to treat many pathological diseases. ...
ANTIOXIDANT AND HEPATOPROTECTIVE EFFECTS OF METHANOLIC EXTRACT OF ORIGANUM MAJORANA IN CCL4- INDUCED LIVER INJURY IN RATS
Objective: The present study was aimed to evaluate the antioxidant and hepatoprotective activity of methanolic extract of Origanum majorana aerial parts against CCl4 induced hepatotoxicity in rats. Materials and Methods: Wistar rats (150-200 g) were divided into five groups each group containing six rats. Group A treated as normal control receives 1% v/v tween-80, p.o for 14 days. Group B received...
Peptic Ulcer Disease (PUD) is an inflammation along the mucosal lining of esophagus, stomach or duodenum or anywhere in the gastrointestinal tract. PUD is the most common gastrointestinal disorder in clinical practice because of alteration in lifestyle and food habits. The main symptoms related to PUD are Indigestion, heartburns, burning pain or abdominal pain, nausea, vomiting, constipation, bloa...
EVALUATION OF IN VITRO ANTI CANCER ACTIVITY OF HYDROALCOHOLIC FLOWER EXTRACT OF BUTEA MONOSPERMA VAR. LUTEA
Butea monosperma var. lutea, a native of India, is commonly known as “Palash” and popularly known as “Flame of Forest.” Traditionally it has been found that flowers have antimicrobial, wound healing, antifungal, antidiarrhoeal, hypoglycemic, hepatoprotective, antioxidant, anthelmintic, anti-convulsive, antistress, antidiabetic, anti-inflammatory activity. In the present study, crude hydroa...
THE STUDY EFFECT OF HYDRO-ALCOHOLIC EXTRACT OF JAPANESE PERSIMMON FRUIT ON FORMALIN-INDUCED INFLAMMATION IN THE RAT
Acute and chronic inflammation is the most important issue in the field of health. Also, due to the side effects of synthetic drugs, herbal products are widely used in the control of inflammation. In this study was investigated the effect of a hydro-alcoholic extract of Japanese persimmon fruit on the formalin-induced inflammation in the rat paw. 30 male Wistar rats were divided into 5 groups: neg...
PRELIMINARY PHYTOCHEMICAL SCREENING OF TWO MEDICINAL PLANTS -SOLANUM NIGRUM LINN. AND LEUCAS ASPERA (WILLD.) LINN.
The medicinal plants are useful for healing, as well as, for curing of human diseases because of the presence of phytochemical constituents. Phytochemicals are naturally occurring in the medicinal plants, leaves, vegetables, and roots that have defense mechanism and protect from various diseases. The leaves of Solanum are used to treat mouth ulcers that happen during winter periods in Tamil Nadu. ...
BIOLOGICAL EVALUATION OF IN VIVO DIURETIC AND ANTIUROLITHIATIC ACTIVITIES OF LEAF EXTRACTS OF MELOCHIA CORCHORIFOLIA
The present study was investigated to establish the diuretic and antiurolithiatic activities of chloroform and ethanolic leaf extract of Melochia corchorifolia. The chloroform and ethanolic leaf extract were administered to experimental rats orally at a dose of 200 mg/ kg and 400 mg/kg. Furosemide (5 mg/kg) was used as reference standard for diuretic activity. The parameters measured for diuretic ...
IN SILICO PREDICTION OF RIBOSWITCH AS A POTENTIAL DRUG TARGET AND DESIGN OF ITS OPTIMAL INHIBITORS AND PHARMACOPHORE FOR BACILLUS CEREUS
Bacillus cereus is a gram-positive, rod-shaped, motile, beta hemolytic bacteria. These bacteria cause foodborne illness, severe nausea, vomiting, diarrhea, and keratitis. Foodborne illness caused by Bacillus cereus occurs because of the bacterial endospores survival in improperly cooked food. The bacteria produce enterotoxins having high resistance against heat and acids, and they cause the diarrh...