Volume 13 (2026) - Issue 7, July
Review Articles
PHYTOCHEMICAL INTERVENTIONS IN DIABETES MELLITUS: A TRANSITION FROM CONVENTIONAL THERAPY TO INTEGRATIVE MANAGEMENT
Diabetes mellitus is a long -term condition that affects how the body processes glucose, leading to constantly high blood sugar levels due to issues with insulin production and after effects. The widespread incident of diabetes is increasing, and it is associated with owing to sedentary lifestyles, obesity, unhealthy dietary habits, genetic predisposition, and environmental factors. Chronic hyperg...
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A COMPREHENSIVE REVIEW ON SWIETENIA MACROPHYLLA KING: CHEMICAL CONSTITUENTS, PHARMACOLOGICAL ACTIVITIES, TOXICITY AND SAFETY ANALYSIS
Swietenia macrophylla King, widely recognized as big-leaf mahogany or sky fruit, is a highly prized tropical hardwood species belonging to the Meliaceae family traditionally used for managing diabetes, hypertension, inflammation, and various other ailments. Despite growing research interest, existing studies remain fragmented, largely limited to in vitro and acute animal models, with significant v...
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FROM TRADITIONAL USE TO MOLECULAR PHARMACOLOGY: AN UPDATED INTEGRATIVE REVIEW OF CLERODENDRUM INERME (L.)
Clerodendrum inerme (L.) [syn. Volkameria inermis] is a traditional medicinal plant used to treat against viral, neurological, metabolic, and inflammatory illnesses. It had not had a comprehensive synthesis of its traditional knowledge and up to date molecular pharmacology even after a number of experimental research. Concentrating on mechanistic data, the present research tries critically to eval...
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INTEGRATION OF HERBAL MEDICINES WITH CURRENT NANOTECHNOLOGY; A NEW ERA IN OBESITY MANAGEMENT IN FUTURE
Obesity and overweight is excessive or abnormal accumulation of fat in body that presents a risk to health. Overweight and obesity have reached epidemic proportions, with over four million individuals dying every year as a result of their condition. Different approaches comprising biological sources, different drug therapy, have been used in obesity treatment; though, these unoriginal selections l...
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Research Articles
PHYTOCHEMICAL SCREENING, ACUTE TOXICITY, ANTIBACTERIAL AND ANTITUSSIVE EFFECTS OF THE AQUEOUS EXTRACT OF THE LEAVES OF HYMENOCARDIA ACIDA TUL.
This study aims at valorizing the leaves of Hymenocardia acida Tul., a medicinal plant traditionally used in the Republic of Congo and other African countries, for healing cough and respiratory infections. The aqueous extract, prepared by decoction, showed a low acute toxicity in mice (LD50 > 5000 mg/kg). The phytochemical screening revealed the presence of flavonoids, condensed tannins, saponi...
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EVALUATION OF PHYTOCHEMICAL COMPOSITION AND ANTHELMINTIC EFFICACY OF AQUEOUS EXTRACTS FROM THREE BANGLADESHI MEDICINAL PLANTS
The evolution of helminthes drug resistance and the increased expense of traditional medications have spurred investigation into medicinal plants as potential alternatives to anthelmintics. Utilizing P. posthuma, the present study focuses on the anthelmintic activity of three traditionally used plants in Bangladesh. Mimosa pudica (family: fabaceae), Terminalia bellirica (family: Combretaceae), Cal...
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EVALUATION OF THE ANTI-DIABETIC EFFECTS OF TINOSPORA CORDIFOLIA LEAF EXTRACT ON DIABETIC RATS INDUCED BY STREPTOZOTOCIN
Hyperglycemia due to insulin secretion or action abnormalities, or both, characterizes diabetes mellitus, a chronic metabolic condition. Using streptozotocin (STZ)-induced diabetic Wistar rats, this research aimed to determine whether or not extract from the leaves of Tinospora cordifolia had any anti-diabetic effects. A single intraperitoneal injection of 55 mg/kg streptozotocin was used to devel...
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COMPARATIVE IN-VITRO ANTIOXIDANT ACTIVITY OF PUNICA GRANATUM PEEL AND VITIS VINIFERA SEEDS
Oxidative stress caused by free radicals contributes significantly to aging and various chronic diseases, including cardiovascular disorders, cancer, diabetes mellitus, and neurodegenerative conditions. Natural antioxidants from plant sources have gained scientific attention due to their therapeutic potential and safer profile compared to synthetic antioxidants. The present study comparatively eva...
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PHARMACOLOGICAL EVALUATION OF THE METHANOLIC EXTRACT OF MORINDA CITRIFOLIA FRUIT FOR ANTI ASTHMATIC, ANTI OXIDANT AND ANTI- INFLAMMATORY ACTIVITIES
Asthma is a chronic respiratory disorder characterized by airway inflammation, bronchoconstriction, and excessive mucus production. This study evaluated the anti-asthmatic, antioxidant, and anti-inflammatory potential of the methanolic fruit extract of Morinda citrifolia (noni), a medicinal plant widely used in traditional herbal medicine. Dried fruits were shade-dried, powdered, and extracted wit...
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FORMULATION AND EVALUATION OF HERBAL SUNSCREEN CREAM USING SESAME OIL
Exposure to ultraviolet (UV) radiation from sunlight is a major cause of skin damage, premature aging, and skin cancer. Sunscreen creams are widely used to protect the skin from harmful UV rays; however, the long-term use of synthetic sunscreens may cause skin irritation and other adverse effects. Therefore, there is growing interest in the development of herbal sunscreen formulations using natura...
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DEVELOPMENT AND VALIDATION OF A DENSITOMETRIC HPTLC METHOD FOR QUANTIFICATION OF OPUNTIOL IN OPUNTIA ELATIOR MILL.
Opuntiol is a biologically active flavonol present in Opuntia elatior Mill. (Cactaceae) that exhibits significant pharmacological activities such as antioxidant, anti inflammatory and anticancer effects. Reliable analytical methods are therefore required for its quantitative estimation in plant extracts and pharmaceutical preparations. The present study aimed to develop and validate a rapid, sensi...
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A CYTOTOXIC STEROID FROM BERRIES OF SOLANUM INCANUM GROWING IN OMAN
In pursuit of anticancer metabolites from natural sources, we examined organic extracts of Solanum incanum berries collected in Oman. The ethyl acetate fraction demonstrated significant inhibition of Carbonic Anhydrase (CA) activity, with an IC₅₀ value of 20.20 ± 1.2 µg/ml. From this fraction, a β-sitosterol derivative was isolated and shown to suppress the proliferation of MCF-7 breast...
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