A CYTOTOXIC STEROID FROM BERRIES OF SOLANUM INCANUM GROWING IN OMAN
AbstractIn pursuit of anticancer metabolites from natural sources, we examined organic extracts of Solanum incanum berries collected in Oman. The ethyl acetate fraction demonstrated significant inhibition of Carbonic Anhydrase (CA) activity, with an IC₅₀ value of 20.20 ± 1.2 µg/ml. From this fraction, a β-sitosterol derivative was isolated and shown to suppress the proliferation of MCF-7 breast cancer cells by 71.5% in the MTT assay. These findings suggest that S. incanum represents a promising source of potential anticancer agents.
Article Information
12
721-725
490 KB
44
English
IJP
Z. A. Daway, A. M. Weli, J. Shaikh, M. S. Akhtar and S. A. Said *
School of Pharmacy, College of Health Sciences, University of Nizwa Oman PB 33, PC 616, Nizwa, Oman.
sadri@unizwa.edu.om
09 June 2026
23 June 2026
29 June 2026
10.13040/IJPSR.0975-8232.IJP.13(7).721-25
01 July 2026
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