EVALUATION OF PHYTOCHEMICAL COMPOSITION AND ANTHELMINTIC EFFICACY OF AQUEOUS EXTRACTS FROM THREE BANGLADESHI MEDICINAL PLANTS
AbstractThe evolution of helminthes drug resistance and the increased expense of traditional medications have spurred investigation into medicinal plants as potential alternatives to anthelmintics. Utilizing P. posthuma, the present study focuses on the anthelmintic activity of three traditionally used plants in Bangladesh. Mimosa pudica (family: fabaceae), Terminalia bellirica (family: Combretaceae), Calotropis gigantea (family: Apocynaceae). At all tested concentrations (25, 50 and 100 mg/ml), of the plant extract showed a significant anthelmintic effect. The highest activity or effectiveness was observed at 100 mg/ml. At these maximum concentrations, Calotropis gigantea showed the most potent anthelmintic effect among the plants, achieving paralysis in 19 ±5 minutes and death time in 86 ± minutes. This was succeeded by Terminalia bellirica (paralysis at 43 ±5min and death at 185±5 minutes) and Mimosa pudica (paralysis at 58 ± 5 minutes and death at 229 ±5 minutes). This result supports the traditional use of these plant-based anthelmintic agents.
Article Information
6
678-682
480 KB
4
English
IJP
Mahmuda Binte Amin, Nusrat Jahan Maisha, Shanta Akter, Tanjina Akter Tanjina, Mt. Farzana Yasmin, Md. Sohel Rana and Pritesh Ranjan Dash *
Department of Pharmacy, ASA University Bangladesh, Shyamoli, Dhaka, Bangladesh.
pritesh.ju@gmail.com
13 June 2026
23 June 2026
29 June 2026
10.13040/IJPSR.0975-8232.IJP.13(7).678-82
01 July 2026
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