Posted by admin on Oct 20, 2015 in |
The proliferation of β-cells is the main contributor to the mass cell maintenance in the pancreatic islets. In our earlier work the suppression of β-cell growth by aggregated peptide hormone of the pancreas, amylin, has been proved. The in-vitro protection of the cells from aggregated amylin-associated death by several plant extracts and their constituents has been shown. In the present work, the development of β-cells was suppressed preliminary by aggregated amylin. Then, the ethanol extracts of rose petals (Rosa damascena), melilot (Melilotus officinalis), leaves of grape (Vitis vinifera) and sorrel (Rumex Confertus) and the phenol glycoside fraction of rose petals were added to the cultivation medium, and the growth of cells suppressed by aggregate amylin was observed. The promotion of cells viability was registered with the trypan blue exclusion test and the DNA-comet analysis. In the other series of experiments, the reverse of pre-formed amylin aggregates in the presence of several plant preparations was registered using Thioflavin T fluorescence. The significant linear correlation (r = 0.75, p=0.02) between two...
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Posted by admin on Sep 2, 2015 in |
The present study was investigated to determine the possible phytochemical components from the solvents such as hexane, ethyl acetate and ethanolic extract of Aerva lanata. Among the phytochemical screening of these extracts, ethanolic extract showed that the whole plant was rich in carbohydrate, tannin, flavonoids, quinones, cardiac glycosides, phenols, and coumarins. Further, the study was extended by analyzing the antioxidant potential using DPPH method. Among all the extracts ethanolic extract showed better antioxidant activity at the concentration of 75 µg/ml when compared to other...
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Posted by admin on Sep 2, 2015 in |
The aim of the present study is the phytochemical screening of gum of Curcuma amada (Mango ginger). Natural gums are economic, easily available and found useful as a tablet binder. The phytochemical properties of a gum obtained from the rhizomes of Curcuma amada were characterized by various test including a test for steroids, tannins, flavonoids, amino acids, carbohydrates, and glycosides. All of the test except for carbohydrates were negative confirms the presence of...
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Posted by admin on Sep 2, 2015 in |
Plants have been used for centuries as a remedy for human diseases because they contain phytochemical components of therapeutic values. Hexane, ethyl acetate and ethanolic extract of Premna latifolia were investigated for phytochemical constituent and antioxidant activity. The phytochemical constituent was investigated using standard chemical methods. Further, the study was extended by analyzing the antioxidant potential using DPPH method. The results showed that ethanolic extract showed a significant number of phytoconstituents and better radical scavenging activity at the concentration of 75...
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Posted by admin on Sep 2, 2015 in |
Dandruff is a common disorder affecting the scalp. Malassezia furfur, the lipophilic dimorphic yeast-like fungus is the main causative agent of dandruff. In recent years plant-based products are widely used as the therapeutic weapon to cure human disorders. The plant Garcinia indica (Kokam) belonging to family Clusiaceae native to India is one of such plants which has shown many therapeutic uses. One part of the present study shows that the optimum conditions for the growth of Malassezia furfur were on sabouraud’s dextrose liquid medium supplemented with corn oil at 30 °C with pH ranging between 8 and 9 and the other part emphasizes on the screening of M. furfur against fractions separated from fruit rinds of G. indica. Out of three screened fractions (Methanolic extract, water fraction and ethyl acetate fraction), ethyl acetate fraction showed a good zone of inhibition 18.2 ± 0.3 mm and 22.6 ± 1.22 mm at 75 and 100% concentration...
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