Posted by admin on Jun 30, 2022 in |
Phytopharmacology is always a vital way for drug discovery. Antibiotic resistance is rising as a challenging threat day by day. Diarrhea and pain are always common problems. The present study was designed to evaluate the Analgesic, Antidiarrhoeal, and Antibacterial activities of ethanol extracts of leaf of Limnophila polystachya Benth by different methods. The analgesic activity of the samples was studied using the acetic acid-induced writhing model in mice. The Thomas method observed castor oil-induced antidiarrheal activity, and antimicrobial activity was monitored by the disc diffusion method. At a higher dose (500 mg/kg), Limnophila polystachya Benth inhibited 65.79 % and 63.16 % writhing of stem and leaf acetone extracts, respectively, compared to standard drug Diclofenac sodium inhibited 78.07 %writhing. Further study is needed to find possible active ingredients and mechanisms of action as well. At a higher dose (500 mg/kg) of the acetone stem and leaf extracts, significant inhibition of 50.58 and 52.87 % of characteristic diarrhoeal feces was observed, respectively, and at a lower dose (250 mg/kg) of both...
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Posted by admin on Jun 30, 2022 in |
Cupressus macrocarpa (C. macrocarpa) is an evergreen tree with medicinal uses. The essential oil of C. macrocarpa possesses a powerful antimicrobial and antifungal effect against several bacteria and fungi. We aimed of this study to evaluate the antibacterial activity of C. macrocarpa. Fresh leaves of C. macrocarpa were collected and dried in the shade at room temperature. The essential oil was obtained using hydrodistillation, and yield was recorded. The antibacterial activity of the essential oil against Staphylococcus aureus, Pseudomonas aeruginosa and Proteus vulgaris was examined, and minimal inhibitory concentration (MIC) was determined using a microdilution assay. As a result, the yield of essential oil from dried and fresh leaves was 0.39% and 0.4%, respectively. The MIC was 0.01 (v/v) for both Staphylococcus aureus and Proteus vulgaris, where the essential oil exhibited lower activity against Pseudomonas aeruginosa with a MIC of 0.04 (v/v). These results show the importance of using Cupressus macrocarpa essential oil to treat infection of several known resistant...
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Posted by admin on Jun 30, 2022 in |
Carissa carandas Linn. is an evergreen plant of the Apocynaceae family. It is native to India and also found in Bangladesh, Sri Lanka, Indonesia, Malaysia, Pakistan, and Myanmar. Almost every part of these plants has been investigated for various pharmacological activities. Among all parts, leaves are less investigated. The present study explores the hepatoprotective activity of 60 % ethanolic extract of leaves of Carissa carandas Linn. Extraction of fresh mature leaves by the process of maceration using Petroleum ether gave 0.84 gm crude extract and a yield of 1.68 %. Extraction by using 60 % Ethanol gave 6.9 gm and a yield of 13.8 %. This crude extract was investigated for the evaluation of a hepatoprotective activity. The carbon tetrachloride (CCl4) induced method was used to study hepatoprotective activity. The extract showed significant dose-dependent hepatoprotective activity when compared with negative control group as the release of enzymes and bilirubin decreased with increasing dose of...
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Posted by admin on Jun 30, 2022 in |
The study focuses on the green synthesis of silver sulfide nanoparticles using aqueous Senna occidentalis (L.) extract as reducing, capping, and stabilizing agents. Fourier Transform Infra-red Spectroscopy (FTIR) and Scanning electron microscopy (SEM) characterized the synthesized silver sulfide nanoparticles. FT-IR spectrum of Senna occidentalis leaves aqueous extract as shown in Fig. 3 below shows a number of peaks, thus reflecting its complex nature. The bands at 3175cm-1 is characteristic of the alcohol/phenol –OH stretching vibration, 2361.44cm-1 an attribute O=C= Stretching representing carbon dioxide. The weak peak at 1594cm-1 is assigned for C=O bending, indicating carboxylic acid, and the band at 995cm-1 represents the C=C bending signifying alkene. Fig. 4 below shows the FTIR result of the synthesized silver sulfide nanoparticle at different bands. The bands at 3785 and 3703 cm-1 correspond to O-H stretching vibration, indicating the presence of alcohol/phenol; the peak at 3406 cm-1 reflects N-H stretching of alphatic primary amine. Bands at 2919 and 2855.82cm-1 correspond to the C-H stretching of aromatic compounds. The band at 1713.88cm-1...
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Posted by admin on May 31, 2022 in |
Vetiveria zizanioides (L.) Nash has been suggested in the Indian system of medicine as the roots of Usira for a number of diseases such as fever, dysuria, fatigue syndrome, wound healing, skin disorders, etc. (Jvara, Trishna, Mutrakrachhra, Vrana). This will be created helpfulness towards this medicinal plant and for preparation of different Ayurvedic formulations i.e Usira sava, Yogarajaguggulu, Sadanga Kvatha Curna. The objective of the present study is to develop the pharmacognostic and phytochemical profiles of Vetiveria zizanioides (L.) Nash root. The present study considers the detail investigation of macroscopy, microscopy, preliminary qualitative phytochemical analysis, physicochemical evaluations and HPTLC chromatography profiling. Microscopical investigation shows the presence of rectangular cells of epidermis, elongated and polygonal parenchyma groups, oval aerenchymatous cells, cork cells, elongated cells sclereids, sclerenchymatous stone cells, groups of sclerenchymatous fiber, prismatic crystals of calcium oxalate and starch grains. The presence of various secondary metabolites was confirmed by phytochemical screening and HPTLC profiling. Identification and authentication of roots may be helpful from botanical and chemical screening data for developing...
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