Posted by admin on Feb 28, 2015 in |
Emergence of multidrug-resistant strains of pathogens and adverse effects of antibiotics have rapid lead search for new antimicrobials. Medicinal plants have gained more importance as a source of alternative and effective drugs. Euclea racemosa sub sp. schimperi (DC.) Dandy (Ebenaceae) has many traditional uses against infections and related disorders. The objective of this study was to evaluate the antibacterial potential and identify major phytochemical groups in root extracts of E. racemosa. Root part of the plant was extracted by maceration using methanol, acetone, and chloroform. Extracts were subjected to antibacterial screening against seven bacteria strains: Staphylococcus aureus (ATCC215223), Streptococcus pneumonia (ATCC49619), Streptococcus pyogenes (ATCC19615), Escherichia coli (ATCC259292), Klebsiella pneumonia (ATCC70060), Pseudomonas aeruginosa (ATCC27853), and Salmonella typhi (ATCC1912/R). Well, the diffusion method was used to perform the antibacterial screening. Determination of minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and phytochemical screening was also done on the extracts. Results indicated that the different extracts displayed significant (P<0.05) antibacterial activities and the methanol extract were more active. Flavonoids, glycosides, phenols, saponins,...
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Posted by admin on Feb 1, 2015 in |
Andrographis paniculata Nees is a plant that has been effectively used in traditional Asian medicines for centuries. It’s perceived “blood purifying” property and also for medicinal properties. The present paper deals to study the phytochemical screening of Andrographis paniculata for various medicinally important compounds. In the present investigation, it was found that phenols, alkaloids, tannins, flavonoids are present in leaves, stem, and root of the plant. Saponin is...
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Posted by admin on Feb 1, 2015 in |
The present study was aimed to investigate the cytotoxic activity of different fractions (petroleum ether, ethyl acetate & chloroform) of the rhizome of Alpinia nigra – a plant belonging to the family Zingiberaceae. The rhizome of Alpinia nigra was extracted with organic solvent, and the extracts were fractionated by using three fractions (petroleum ether, ethyl acetate & chloroform). The petroleum ether, ethyl acetate & chloroform soluble fractions of Alpinia nigra were screened for cytotoxic activity using brine shrimp lethality bioassay. A reputed cytotoxic agent vincristine sulphate was used as a positive control. From the results of the brine shrimp lethality bioassay it can be well predicted that petroleum ether, ethyl acetate and chloroform-soluble fractions of Alpinia nigra rhizome possess cytotoxic principles (with LC50 1.245 mg/ml and LC50 2.151 mg/ml and LC50 2.737 mg/ml respectively) comparison with positive control vincristine sulphate (with LC50 0.563 mg/ml). All the extracts of Alpinia nigra showed moderate cytotoxic activities in this experiment. The results of this study are highly...
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Posted by admin on Feb 1, 2015 in |
The present study was to analyze the occurrence of mycorrhizal diversity in 20 medicinal plants of Vriddhachalam, Cuddalore District, Tamil Nadu and to explore for structures correlated to the possible functional position of the symbiosis. Arbuscular mycorrhizal fungal colonization ranged from 24-81%. The highest infection was found in Justicia gendarussa and lowest in Naregamia alata. AM fungal spore population with a range of 140 to 620 in100 g of rhizosphere soils was detected. The maximum spore population was observed in the species, Maranta arundinaceae (620/100g of soil) and the minimum in Achyranthes aspera (140/100g of soil). The AMfungal species were isolated which belongs to four genera (Aculospora, Gigaspora, Glomus and Scutellospora) and among them, Glomus was dominant genera. The soil pH was also...
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Posted by admin on Feb 1, 2015 in |
Pterospermum acerifolium is a common to plant in India is considered carminative, stimulant and emmenagogue. In the present study, the ethanol extract of the bark of Pterospermum acerifolium has been evaluated for Neurochemical study. Treatment with ethanolic extract of Pterospermum acerifolium was found to significantly decrease the serum levels of adrenocorticotropic hormone (ACTH), corticosterone (CORT) and -endorphin (-EP) as well as the brain and serum level of norepinephrine (NE). Furthermore, ethanolic extract of Pterospermum acerifolium was able to significantly reverse the chronic stress by decreasing the brain and serum levels of the monoamine neurotransmitters dopamine (DA), 5-hydroxytryptamine (5-HT). The results obtained from this study suggested that the memory-enhancing effect of ethanolic extract of Pterospermum acerifolium was mediated through regulations of neurochemical and neuroendocrine systems. From the present study, it was concluded that herbal drugs could be potentially used to control the state of CNS disorders. Further investigations are, however, necessary to explore mechanism(s) of action involved in these pharmacological activities....
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