Posted by admin on Aug 13, 2015 in |
A simple and rapid method for the determination of mexiletine in pharmaceutical preparations was developed and validated using linear sweep voltammetry (LSV). The proposed method was based on electrochemical oxidation of mexiletine at a platinum electrode in an acetonitrile solution containing 0.1M LiCIO4. The well-defined an oxidation peak was observed at +1.11 V. The calibration curve was linear for mexiletine at the concentration range of 5-70 µg/mL for LSV method. Intra- and inter-day precision values for mexiletine were less than 2.73, and accuracy (relative error) was better than 3.89%. The mean recovery of mexiletine was 100.1% for a pharmaceutical preparation. No interference was found excipient at the selected assay conditions. The method was found to be specific, precise and accurate. The method was applied for the quality control of commercial mexiletine capsule form to quantify the drug and to check the formulation content...
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Posted by admin on Aug 13, 2015 in |
It was evaluated the damage caused by Bruchus pisorum on the germination ability of pea forage cultivars. Result of damage in seeds with parasitized larva was significant decrease of the germination by 16.4% percentage points, the length and weight of primary radicle by 16.8 and 24.5%, the length and weight of plumule by 12.3 and 14.1%, the vigor index of primary radicle and plumule by 32.5 and 32.8% as well as the germination index by 17.4%. The inhibitory effect was 17.8%. Essential significant changes regarding the studied parameters were found for damaged seeds with bruchid emergence hole. There the germination decrease by 58.3% percentage points, the length and weight of primary radicle by 34.1 and 36.2%, the vigor index of primary radicle and plumule by 81.1 and 82.1% as well as the germination index by 83.1%. The inhibitory effect was on average 58.3%. The damaged seeds with parasitoid emergence hole provided the better possibility for growth, development of plants and stable yields. As tolerant to damage by pest distinguished...
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Posted by admin on Jul 13, 2015 in |
Strobilanthes sessilis Nees is a small perennial shrub, found on Kas plateau of the Western Ghats in India. Its standardized Marathi name is Mal Karvy. This shrub belongs to the genus Strobilanthes which was first scientifically described by Nees in the 19th century. Scientific information on its Pharmacognosy, Phytochemistry is very scant. Hence, the current study describes some Pharmacognostical, Physiochemical and Phytochemical investigations undertaken on the leaves of one of the species of the genus Strobilanthes, namely Strobilanthes sessilis Nees belonging to the family Acanthaceae. The present investigation was undertaken for research with an objective of drawing attention on those scarce species as well as a reference for further scientific...
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Posted by admin on Jul 13, 2015 in |
Oroxylum indicum Vent., Bignoniaceae is one such plant which is extensively used in the Indian system of medicine as an essential ingredients ‘Dashmula’ and also one of the important constituents of a reputed Ayurvedic formulation ‘Chyavanprash.’ The drug consists of root bark of Oroxylum indicum Vent., Bignoniaceae. Identification and quality of the raw drug are necessary for their therapeutic effects. It is, therefore, become essential to search for the possible quality control parameters to ensure the quality of the raw drug by pharmacognostical investigations. The microscopical character of root bark is characterized by cork cells, which are varying interrupted by some stone cell, cork cambium, phelloderm, stone cell. Powder of root bark shown stone cells, fragments of cork, phloem fibers, vessels, and tracheids. TLC of extract shown spots in the solvent system and physicochemical parameters of the plant was found like ash value, aqueous & alcoholic extractive value, total sugars, starch, and...
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Posted by admin on Jul 13, 2015 in |
The leaf galls of Mangifera indica L. are very characteristic and possess medicinal properties, due to their phytochemical profile. Hence, a pharmacognostic and phytochemical study was carried out. The microscopic evaluation of leaf gall powder of Mangifera indica revealed the presence of calcium oxalate crystals, cork cells with resin and sclerites. The anatomy of mature galls exhibited characteristic anomalous growth with an outer cork layer with cell differentiation. The young galls were only parenchymatous. They also showed the presence of tannins, alkaloids, terpenoids, and flavonoids. The flavanoid in the gall tissue was 60% more than the normal leaf tissue. The fluorescence study of the powder showed very characteristic bright yellow fluorescence indicating the presence of intense flavanoids. Water soluble and acid insoluble ash was found to be 24% and 10% respectively with a moisture content of 0.6%. Further, an in-vitro study on various therapeutic properties of leaf galls will be more...
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