EVALUATION OF PRESERVATIVE EFFECTIVENESS IN ANTACID, COUGH SYRUP AND OPHTHALMIC SOLUTION BY MICROBIAL CHALLENGE TEST
Pharmaceutical preparations having high water content face the problem of microbial spoilage which affects consumer safety. Control on such problem is generally done by the addition of a specific preservative to these pharmaceutical preparations, but sometimes some physical changes and clinical hazards are observed even after the addition of preservatives. The present study aimed to evaluate and c...
ANALGESIC ACTIVITY OF CINNAMALDEHYDE PER SE AND IT’S INTERACTION WITH DICLOFENAC SODIUM AND PENTAZOCINE IN SWISS ALBINO MICE.
Cinnamon is one of the best-known spices used as herbal medicine. Cinnamaldehyde is the most important constituents of cinnamon. The present study was aimed to evaluate the analgesic activity of Cinnamaldehyde per se and its interaction with diclofenac sodium and pentazocine in Swiss albino mice. Healthy mice of either sex weighing 20-30 grams were divided into 6 groups of 6 animals each. Peripher...
Rauwolfia serpentina has a great reputation as a miracle medicinal plant, reported in various texts of the indigenous system of medicine. As, free radicals and diseases have great correlation; therefore, in the present study, free radical scavenging activity of methanolic extract (MET) of rhizomes of mature Rauwolfia serpentina was investigated by using CCl4 induced hepatotoxicity model in albino ...
The natural anthracene derivative emodin (1,3,8-trihydroxy-6-methylanthraquinone) is known as an anticancer agent. In the present work, it was isolated for the first time from the ethanol extract of Rumex confertus leaves, widely used in Armenia as a vegetable. It was purified in two-step low-pressure liquid chromatography – a significantly easier and inexpensive procedure compared with those us...
THE LEAF OF NILGIRI RHODODENDRON: A POTENT ANTIMICROBIAL AGENT AGAINST MEDICALLY CRITICAL HUMAN PATHOGENS
Several reports are available for Rhododendron arboreum which is limited to its subspecies nilagiricum. The present study intended to examine the bioactive compounds and the antimicrobial activity of leaf extracts of R. arboreum Sm spp. nilagiricum (Zenker) Tagg against medically important four bacterial (Streptococcus pyogene, Staphylococcus aureus, Escherichia coli, Klebsiella pneumonia) and two...
Proper and normal functioning of the bodily process must be ensured in order to maintain perfect health. Any disturbance in the normal humoral balances whether it is excess, diminution or blockage leads to disease stated Avicenna (980-1037 A.D) the revered Greco Arabic physician and author of world-renowned treatise “Al Qanoon fit tib.” He has treated certain diseases by regulating metabolic p...
PHARMACOGNOSTIC AND PRELIMINARY PHYSIOCHEMICAL INVESTIGATIONS OF PLANT THEVETIA PERUVIANA LEAVES AND FLOWERS
Thevetia peruviana is found distributed throughout tropical parts of India. Their leaves are used as cardiotonic and diuretic. Flowers of plant Thevetia peruviana were reported to possess good medicinal value in the traditional system of medicine; the present investigation deals with macroscopic, microscopic and preliminary phytochemical investigation of flowers of Thevetia peruviana which include...
The traditional Indian medicine - Ayurveda, describes various herbs, fats, oils and minerals with anti-aging as well as wound healing properties. Wounds are the result of injuries to the skin that disrupt the soft tissue. Wound healing can be defined as a complex dynamic process results in the restoration of anatomic continuity and function. Various plant products have been used in the treatment o...
COMPARATIVE STUDY OF ANTIMICROBIAL EFFECT OF NIGELLA SATIVA SEED EXTRACTS FROM DIFFERENT GEOGRAPHIES
Prophet Mohammed calls Nigella sativa seed as a medicine of blessings. Nigella sativa is an herbaceous plant and cultivated in the Middle East, South East Asia and some part of Europe. Nigella sativa seed has been in use in the Middle East, South East Asia and some part of Europe over 2000 years. Until date lot of research, studies are conducted to prove the therapeutic utility of Nigella sativa s...
Moringa oleifera Lam. is the most imperative and legendary species of family Moringaceae. It is called as Soanjna in the local language (Punjabi). It has noteworthy medicinal and nutritional significance for both humans as well as for animals. Traditionally it is recommended to treat many ailments and to contest malnutrition mostly in tropics. It has scores of pharmacological activities such as an...