Elimination and Eradication is an important component of the Global Strategy for combating malaria, and one of the ways of achieving this purpose is blocking the transmission of malaria parasites from humans to mosquito vectors. The ability of Plasmodium to cease asexual replication in the erythrocytes of the human host and commit to the formation of gametes necessary for sexual replication in the...
ANTIDIABETIC POTENTIAL OF IVY GOURD (COCCINIA GRANDIS, FAMILY: CUCURBITACEAE) GROWN IN SRI LANKA: A REVIEW
Leaves of ivy gourd; Coccinia grandis (L.) Voigt (Family: Cucurbitaceae) is one of the well-known leafy vegetables, which has been consumed by Sri Lankans for centuries. The therapeutic potential of ivy gourd against diabetes is brought mainly by its antihyperglycemic, β-cell regenerative, antihyperlipidemic and antioxidant properties. Also, the optimum effective therapeutic dose of the aqueous C...
Kandangkathiri Kirutham (ghee of Solanum xanthocarpum) is a Siddha herbal formulation mentioned in Siddha textbook for the treatment of Ullnaakku Azharchi (Tonsillitis). It contains leaf juice of Kandangkathiri (Solanum xanthocarpum), cow’s ghee, the paste of raw drugs namely Sittrarathai (Alpinia officinarum), Sittramutti (Sida cordifolia), Nerunjil ver (Tribulus terrestris), Chukku (Zingiber o...
The traditional Indian medicine - Ayurveda, describes various herbs, fats, oils and minerals with anti-aging as well as wound healing properties. Wounds are the result of injuries to the skin that disrupt the soft tissue. Wound healing can be defined as a complex dynamic process results in the restoration of anatomic continuity and function. Various plant products have been used in the treatment o...
This study was carried out to evaluate the thrombolytic and membrane stabilizing activities of Launaea sarmentosa plants. The crude methanolic extract of L. sarmentosa (whole plants) was investigated for in-vitro thrombolytic and membrane stabilizing activities at five different concentrations of 2, 4, 6, 8 and 10 mg/ml respectively. In the case of thrombolytic study, it was dose-dependently incre...
The hypolipidemic activity of Aloe vera (Family: Liliaceae) extract has been studied in two models of hyperlipidemia in rats. In an acute model, hyperlipidemia was induced by injecting a single dose of triton WR-1339 (400mg/kg, b.w.) intraperitoneally in rats. Feeding with Aloe vera extract at the dose of 500 mg/ kg, b.w. exerted a significant lipid-lowering effect as assessed by the reversal of p...
For a very long time, plants have been used worldwide as a natural medicine to treat human diseases, and it has been in many parts of the world, plants are used as a safe source of drugs to cure several diseases and conditions through complementary medicine system. In tropical Asia and Africa, Commelina benghalensis is a native plant and is known to have significant pharmacological activities. Thi...
ANTIOXIDANT EFFECT OF CRUDE WATER EXTRACT OF VETIVERIA ZIZANIOIDES (GRAMINEAE) IN MICE WITH ACETAMINOPHEN INDUCED HEPATOTOXICITY
Acetaminophen (APAP) is widely used as an analgesic and antipyretic drug. The large dose of APAP results in severe hepatic necrosis due to the oxidative stress. This work evaluates the antioxidant activity of crude water extract of Vetiveria zizanioides roots against a single dose of APAP induced acute hepatotoxicity. Mice were treated with 300 mg/kg of APAP dissolved in saline and fasted for 16 h...
ANTIDIARRHEAL AND ANTIBACTERIAL ACTIVITIES OF HYDROALCOHOLIC EXTRACTS OF SALVIA SCHIMPERI BENTH FROM ETHIOPIA
In Ethiopian folk medicine, aqueous decoction of the leaves of Salvia schimperi is used for treatments of various ailments including diarrhea, however, to date, there appear to have been no reports on the phytochemistry, the antidiarrhoeal and the antimicrobial activity of the plant. In this study, the hydroalcoholic extract of the leaves of S. schimperi was evaluated for its antidiarrheal and ant...
Moringa oleifera Lam. is the most imperative and legendary species of family Moringaceae. It is called as Soanjna in the local language (Punjabi). It has noteworthy medicinal and nutritional significance for both humans as well as for animals. Traditionally it is recommended to treat many ailments and to contest malnutrition mostly in tropics. It has scores of pharmacological activities such as an...