Vitiligo is an acquired idiopathic epidermal pigment loss occurring on the body. The prevalence of the disease is less than 0.5%. Pathogenesis of vitiligo has been intriguing researchers for decades. Basic defect in vitiligo is the disappearance of melanocytes. Several therapies are prescribed for the disease; the most effective one is narrowband UVB phototherapy. Several evidence-based hypotheses...
ANALGESIC ACTIVITY OF CINNAMALDEHYDE PER SE AND IT’S INTERACTION WITH DICLOFENAC SODIUM AND PENTAZOCINE IN SWISS ALBINO MICE.
Cinnamon is one of the best-known spices used as herbal medicine. Cinnamaldehyde is the most important constituents of cinnamon. The present study was aimed to evaluate the analgesic activity of Cinnamaldehyde per se and its interaction with diclofenac sodium and pentazocine in Swiss albino mice. Healthy mice of either sex weighing 20-30 grams were divided into 6 groups of 6 animals each. Peripher...
In the few decades, there has been exponentially growth in the field of herbal medicines. Most of the traditional system of medicine is effective but they lack standardization. So there is a need to develop a standardization technique. Standardization of herbal formulation is essential in order to assess the quality, purity, safety and efficacy of the drug based on their concentration of their pri...
Rauwolfia serpentina has a great reputation as a miracle medicinal plant, reported in various texts of the indigenous system of medicine. As, free radicals and diseases have great correlation; therefore, in the present study, free radical scavenging activity of methanolic extract (MET) of rhizomes of mature Rauwolfia serpentina was investigated by using CCl4 induced hepatotoxicity model in albino ...
The natural anthracene derivative emodin (1,3,8-trihydroxy-6-methylanthraquinone) is known as an anticancer agent. In the present work, it was isolated for the first time from the ethanol extract of Rumex confertus leaves, widely used in Armenia as a vegetable. It was purified in two-step low-pressure liquid chromatography – a significantly easier and inexpensive procedure compared with those us...
THE LEAF OF NILGIRI RHODODENDRON: A POTENT ANTIMICROBIAL AGENT AGAINST MEDICALLY CRITICAL HUMAN PATHOGENS
Several reports are available for Rhododendron arboreum which is limited to its subspecies nilagiricum. The present study intended to examine the bioactive compounds and the antimicrobial activity of leaf extracts of R. arboreum Sm spp. nilagiricum (Zenker) Tagg against medically important four bacterial (Streptococcus pyogene, Staphylococcus aureus, Escherichia coli, Klebsiella pneumonia) and two...
Proper and normal functioning of the bodily process must be ensured in order to maintain perfect health. Any disturbance in the normal humoral balances whether it is excess, diminution or blockage leads to disease stated Avicenna (980-1037 A.D) the revered Greco Arabic physician and author of world-renowned treatise “Al Qanoon fit tib.” He has treated certain diseases by regulating metabolic p...
Cassia fistula Linn. (Family Leguminosae, Subfamily Caesalpinia), a very common Indian plant is known for its medicinal properties. This plant is also known as Indian Laburnum, Yellow shower because of its characteristic yellow flowers in pendulous raceme and with typical branches. It is a native of Tropical Asia. It is widely cultivated in South Africa, Mexico, East Africa, and Brazil. This plant...
PHARMACOGNOSTIC AND PRELIMINARY PHYSIOCHEMICAL INVESTIGATIONS OF PLANT THEVETIA PERUVIANA LEAVES AND FLOWERS
Thevetia peruviana is found distributed throughout tropical parts of India. Their leaves are used as cardiotonic and diuretic. Flowers of plant Thevetia peruviana were reported to possess good medicinal value in the traditional system of medicine; the present investigation deals with macroscopic, microscopic and preliminary phytochemical investigation of flowers of Thevetia peruviana which include...
COMPARATIVE STUDY OF ANTIMICROBIAL EFFECT OF NIGELLA SATIVA SEED EXTRACTS FROM DIFFERENT GEOGRAPHIES
Prophet Mohammed calls Nigella sativa seed as a medicine of blessings. Nigella sativa is an herbaceous plant and cultivated in the Middle East, South East Asia and some part of Europe. Nigella sativa seed has been in use in the Middle East, South East Asia and some part of Europe over 2000 years. Until date lot of research, studies are conducted to prove the therapeutic utility of Nigella sativa s...