Diabetes mellitus (DM) is being one of the major causes of morbidity and mortality, which seriously threatens the health of human beings. Worldwide around 366 million people are found to be affected by diabetes. DM is a chronic condition associated with abnormally high levels of sugar (glucose) in the blood. Absence or insufficient production of insulin, or an inability of the body to properly use...
The Siddha System of Medicine (Traditional Tamil System of medicine), which has been most prevalent in the ancient Tamil land, is the foremost of all other medical systems in the world. Since, ancient times, several diseases have been treated by administration of plant extracts based on traditional medicine. Plants are the only economic source of some well established and important drugs. Indian M...
Our ecosystem is laden with hazardous and non-hazardous wastes that pose a serious threat to bio-existence. Most pharmaceutical formulations contain chemically-synthesized surfactants. The purpose of this work is to suggest an alternative source of surfactant which would also aid in ridding our environment of harmful wastes. Bacillus licheniformis B-4 strain isolated from a hydrocarbon dump site p...
The present study was aimed to investigate the cytotoxic activity of different fractions (petroleum ether, ethyl acetate & chloroform) of the rhizome of Alpinia nigra – a plant belonging to the family Zingiberaceae. The rhizome of Alpinia nigra was extracted with organic solvent, and the extracts were fractionated by using three fractions (petroleum ether, ethyl acetate & chloroform). Th...
MEMBRANE STABILIZATION, INHIBITION OF ‘HISTAMINE AND PROSTAGLANDIN SYNTHESIS’ MEDIATED ANTI INFLAMMATORY RESPONSE OF SOME INDIGENOUS PLANTS
In the present study the anti-inflammatory, analgesic activity and mechanistic pathway of Centratherum anthelminticum (Willd.) Kuntze (CA), Cissus quadrangularis Linn. (CQ) and Kigelia pinnata DC (KP) was tested in rats using carrageenan induced paw edema method. The central analgesic activity was assessed by radiant heat method, hot plate method, and tail immersion method. The peripheral analgesi...
EXPLORE THE ANTIMICROBIAL POTENTIAL FROM ORGANIC SOLVENTS OF BROWN SEAWEED EXTRACTS (SARGASSUM LONGIFOLIUM) ALLEVIATING TO PHARMACEUTICALS
Marine macroalgae Sargassum is commonly referred to as brown seaweeds. Commercially and continuously the pharmaceuticals industries are rapidly growing because always demand for new drug discovery is encouraged. Since, brown seaweeds have ample source of bioactive compounds of primary or secondary metabolites. These potential bioactive compounds interest to improve the pharmaceuticals industry. Th...
CHEMICAL COMPOSITION AND ANTIFUNGAL ACTIVITY OF ESSENTIAL OILS FROM AERIAL PARTS OF MENTHA PIPERITA AND MENTHA ARVENSIS
The present study deals with the chemistry and antifungal activity of essential oil (EO) of two species of Mentha viz. Mentha piperita and Mentha arvensis which was extracted using Clevenger-type apparatus. The percent yield of EO of M. arvensis (2.8%) was found higher than M. piperita (2.1%). Compositional analysis of M. piperita and M. arvensis EO oil by GC-MS revealed the presence of 51 and 35 ...
PRELIMINARY PHYTOCHEMICAL SCREENING AND QUANTIFICATION OF BIOACTIVE COMPOUNDS IN THE LEAVES OF SPINACH (SPINACEAE OLERACEAE L.)
Plants are the sources for a large number of secondary metabolites. Spinacia oleraceae is a green leafy vegetable belonging to Chenopodiaceae family. It is having medicinal properties due to rich nutritional value and is extremely rich in antioxidants. Antioxidant property of the spinach is due to the presence of bioactive compounds. The present study aims to screen the phytochemicals of different...
Vitiligo is an acquired idiopathic epidermal pigment loss occurring on the body. The prevalence of the disease is less than 0.5%. Pathogenesis of vitiligo has been intriguing researchers for decades. Basic defect in vitiligo is the disappearance of melanocytes. Several therapies are prescribed for the disease; the most effective one is narrowband UVB phototherapy. Several evidence-based hypotheses...
MEDICINAL EFFECT OF KAMEELA AND AMRAZE JILDIYA (SKIN DISEASES) DESCRIBED IN UNANI SYSTEM OF MEDICINE AND CURRENT RESEARCH – AN OVERVIEW
Kameela or Kamala is a well known Unani drug which is being used as medicament from centuries for the treatment of Amraze Jildiya (skin disease) by Unani Physicians and also mentioned their medicinal efficacy in Unani Classical text. It is widely scattered perennial shrub or small tree in tropical and subtropical region regions with an altitude below the 1,000 m and is a description to have a broa...