EXPLORE THE ANTIMICROBIAL POTENTIAL FROM ORGANIC SOLVENTS OF BROWN SEAWEED EXTRACTS (SARGASSUM LONGIFOLIUM) ALLEVIATING TO PHARMACEUTICALSAbstract
Marine macroalgae Sargassum is commonly referred to as brown seaweeds. Commercially and continuously the pharmaceuticals industries are rapidly growing because always demand for new drug discovery is encouraged. Since, brown seaweeds have ample source of bioactive compounds of primary or secondary metabolites. These potential bioactive compounds interest to improve the pharmaceuticals industry. This present study was investigated to explore the antibacterial and antifungal activity of the organic solvents of the brown seaweed Sargassum. Phytochemical analysis of Brown seaweeds of Sargassum longifollium with six different organic solvents was analyzed. All the solvents like Dimethyl Sulfoxide (DMSO), Benzene, Acetic acid, hexane, Di Ethyl ether, and Chloroform has the extraction of phytochemical constituents. Among the six solvents, Dimethyl Sulfoxide (DMSO) extract showed a maximum number of phytochemical constituents and antibacterial and antifungal activity when compared to other five solvent extracts. FTIR identified the responsible functional groups in the solvent extract. These results statements be a necessary (or) recommended that the species of brown seaweeds (Sargassum longifolium) having a potential capacity as a source of antimicrobial compounds, which makes them interesting for screening for natural and highly bioactive secondary metabolites products it may lead to the development of new pharmaceutical agents.
Ponnanikajamideen, C .Malarkodi, M. Malini and S. R. Kumar
Environmental Nano Technology Division, Sri Paramakalyani Centre for Environment Sciences, Manonmaniam Sundaranar University, Alwarkurichi, Tamilnadu, India.
15 November 2013
17 December 2013
26 December 2013
01 January 2014