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THROMBOLYTIC AND MEMBRANE STABILIZING ACTIVITIES OF LAUNAEA SARMENTOSA
This study was carried out to evaluate the thrombolytic and membrane stabilizing activities of Launaea sarmentosa plants. The crude methanolic extract of L. sarmentosa (whole plants) was investigated for in-vitro thrombolytic and membrane stabilizing activities at five different concentrations of 2, 4, 6, 8 and 10 mg/ml respectively. In the case of thrombolytic study, it was dose-dependently incre...
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NITRIC OXIDE AS A TARGET FOR HYPERTENSION MANAGEMENT: A REVIEW ARTICLE
High blood pressure is well-established as a leading cause of stroke, ischemic heart disease, and cardiovascular disease. Globally cardiovascular disease accounts for approximately 17 million deaths a year, nearly one third of the total. A number of pharmaceutical agents are available for initial treatment of high BP. These include older molecules such as diuretics and beta-blocking agents, and ne...
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HISTORICAL PERSPECTIVE OF SHAQEEQA (MIGRAINE) WITH SPECIAL REFERENCE TO CONTRIBUTION OF GRECO-ARAB PHYSICIANS
The current practice of medicine indebted much to the knowledge and achievements of the past. It is really surprising that far back Greco-Arab physicians were aware of the various diseases and scientifically mentioned them. Most of the knowledge is still in practice. Modern days practice relies on the fundamentals proposed by them. In the classical text of Unani Medicine, headache is described in ...
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POTENTIAL ANTIOXIDANT ACTIVITIES OF SPONDIAS PINNATA (FAMILY: ANACARDIACEAE) BARK EXTRACT IN RATS WITH STREPTOZOTOCIN INDUCED DIABETES MELLITUS
The present study was to investigate the antioxidant activity of aqueous bark extract of Spondias pinnata (Linn. f.) Kurz (Family: Anacardiaceae) in streptozotocin-induced diabetic rats. The antioxidant activity was evaluated by the activities of liver enzymes, antioxidant enzymes, and the extent of lipid peroxidation (LPO) in the liver of streptozotocin (STZ) ‑diabetic rats. S. pinnata extract ...
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EFFECT OF COMMIPHORA MUKUL IN CHRONIC OXAZOLONE INDUCED MOUSE DERMATITIS MODEL
Aim: The objective of this study was to evaluate the effect of Commiphora mukul on psoriasis. Materials and Methods: Six female Balb/C mice per group of which, the first three groups served as untreated, disease controls and standard (0.1% dexamethasone) respectively. Animals of groups 4, 5 and 6 were applied 0.5, 1 and 2% of the C. mukul extract on both the ears, respectively. Dermatitis was indu...
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ANTIOXIDANT AND ANTIMICROBIAL ACTIVITIES OF ROOT LEAVES AND FLOWERS OF CICHORIUM INTYBUS
A study was conducted to assess root, leaves and flowers extracts of Cichorium intybus for their antimicrobial activities (against four bacterial and fungal strains), antioxidants activities (DPPH, ABTS H2O2 and reducing power assays) and cytotoxicities assays. The results indicate remarkable inhibition of plant extracts for the growth of all bacterial and fungal strains as well as appropriate MIC...
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NEUROPROTECTIVE ACTIVITY OF ASCOPHYLLUM NODOSUM ON EXPERIMENTLLY INDUCED GLOBAL CEREBRAL ISCHEMIA/REPERFUSION INJURY IN MICE
Background: Ascophyllum nodosum has been used in oriental medicine to treat a variety of remedies, including some neurological disorders. Ascophyllum nodosum rich in phenolic antioxidant (rich in polyphenol) have been identified as major active component exhibiting antioxidant, anti-inflammatory and neuroprotective effects. The present study is to evaluate the neuroprotective effect of Ascophyllum...
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PHYTOCHEMICAL AND ETHNO BOTANICAL STUDY OF MEDICINAL PLANTS USED TO TREAT ECTOPARASITES IN RUMINANT ANIMALS IN EASTERN TIGRAY, NORTHERN ETHIOPIA
The use of ethnobotany practices to treat and control ruminant livestock diseases is old practices in large part of the world. To investigate Traditional medicinal plants used to treat ectoparasites in ruminant animals’ Semi-structured interview, observation and field guided walks were used with ruminant livestock owner, local and traditional healers who had willing to share their indigenous kno...
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BIOLOGICAL ACTIVITIES OF EXTRACTS AND SEASONAL VARIATION IN ESSENTIAL OIL COMPOSITION FROM MYRCIARIA GLAZIOVIANA (MYRTACEAE)
Extracts from leaves, stems and flower buds of Myrciaria glazioviana were analyzed for their antioxidant and anticholinesterase activity. The methanolic extracts showed the best results in reducing power (623.52 - 806.15 mg AA/g of extract), DPPH radical scavenging (IC50 = 9.77 - 14.06 µg/mL) and lipid peroxidation inhibition activity (21.30 - 66.80%). These data were correlated to the total phen...
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ANTI-DIABETIC AND ANTI-OXIDANT PROPERTIES OF ALOE VERA IN ALLOXAN INDUCED DIABETIC RATS
The present study was undertaken to evaluate antidiabetic and antioxidant activities of Aloe vera (A. vera, Ghee-kuwar; family: Liliaceae) extract against alloxan-induced diabetes in male adult Charles foster rats to scientifically validate its use against diabetes. A. vera extract and a standard drug (glibenclamide) prepared in aqueous gum acacia (2%, w/v) suspension and fed orally to alloxan ind...
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