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STUDY OF PLANTS WITH D-CHIRO-INOSITOL AND ITS DERIVATIVES ON DIABETES
Diabetes is an endocrine disorder, and it is due to a deficiency in secretion or action of insulin. The increased prevalence of diabetes in recent decades has made it to severe risk for public health. Human always has great consideration to plants for treatment of illnesses, especially diabetes and it is probably due to common ingredients with mammalian cells such as inositol, especially isomer of...
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IN-SITU RAFT FORMING SYSTEM: A REVIEW
Oral delivery of the drug is the preferable drug delivery due to the ease of administration, patient compliance, and flexibility in the formulations. In recent era, various technologies have been made in research and development of controlled release oral drug delivery system to overcome various physiological difficulties such as variation in gastric retention and emptying time. Conventional oral ...
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ANTIFERTILITY EFFECT OF CAESALPINIA BONDUCELLA (L.) FLEMING IN MALE WISTAR RAT
To evaluate the possible antifertility effect of 50% ethanolic extract of C. bonducella seeds in male rats. Adult, healthy, male Wistar rats were randomly selected and divided into three groups each having 7 rats. Group, I rats were treated with vehicle only and served as control. While group II and Group III rats were orally treated with C. bonducella extract at 200 mg and 400 mg/kg body weight/d...
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MORTALITY AND REPELLENT ACTIVITY OF CLERODENDRUM VISCOSUM VENT. (VERBENACEAE) AGAINST SITOPHILUS ORYZAE (COLEOPTERA: CURCULIONIDAE)
In continuation of our study we have screened out the root, leaf, and stem of C. viscosum against rice weevil, S. oryzae extracted into ethanol, ethyl acetate, and chloroform. A correlation was found between the insecticidal and repellent activity observed by residual film assay technique and repellency test. It is interesting to note that these plant extracts showed higher to less mortality activ...
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PHARMACOGNOSTIC AND PRELIMINARY PHYTOCHEMICAL SCREENING OF LEAVES OF RAPHANUS SATIVUS, LINN.
Raphanus sativus commonly known as radish is cultivated as a crop and having various medicinal uses. It is cultivated all over the world as an edible root vegetable. The present study deals with the pharmacognostic, preliminary phytochemical investigation of Raphanus sativus, Linn. belonging to family Cruciferae. In this, pharmacognostic studies are concerned for the determination of physicochemic...
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BIOLOGICAL EVALUATION OF IN VIVO DIURETIC AND ANTIUROLITHIATIC ACTIVITIES OF LEAF EXTRACTS OF MELOCHIA CORCHORIFOLIA
The present study was investigated to establish the diuretic and antiurolithiatic activities of chloroform and ethanolic leaf extract of Melochia corchorifolia. The chloroform and ethanolic leaf extract were administered to experimental rats orally at a dose of 200 mg/ kg and 400 mg/kg. Furosemide (5 mg/kg) was used as reference standard for diuretic activity. The parameters measured for diuretic ...
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PHYTOCHEMICAL AND PHARMACOLOGICAL IMPORTANCE OF CURCUMA AROMATICA SALISB: A REVIEW
Curcuma aromatica salisb, which belongs to the Zingiberaceae family, is a perennial herb. The rhizome of the plant consists of alkaloids, curcuminoids, flavonoids, tannins, and terpenoids which are reported to be the reasons for its various pharmacological properties. The extraction of compounds in different solvents shows that the plant contains neocurdione, curdione and germacrone as its major c...
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CURRENT ADVANCES IN NANOTECHNOLOGY FOR DELIVERY OF ANTI-DIABETIC DRUGS: A REVIEW
Diabetes mellitus (DM) is being one of the major causes of morbidity and mortality, which seriously threatens the health of human beings. Worldwide around 366 million people are found to be affected by diabetes. DM is a chronic condition associated with abnormally high levels of sugar (glucose) in the blood. Absence or insufficient production of insulin, or an inability of the body to properly use...
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REGULATION OF WNT GENES IN STEM CELLS DEVELOPMENT AND ORGANOGENESIS
Stem cell biology, many signals regulated stem cells and organ development. Wnt factors play a crucial role in stem cells development and induced signaling pathway in stem cells. Wnt signals classified as a canonical and non-canonical pathway. Wnt factors regulated both pathways for stem cells self-renewal, proliferation, and differentiation. Wnt canonical pathway induced by Wnt1, Wnt2, Wnt2b, Wnt...
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BIOSURFACTANT PRODUCED BY NOVEL HALO-THERMOPHILIC BACTERIAL STRAIN FROM UNCONVENTIONAL SUBSTRATES
Our ecosystem is laden with hazardous and non-hazardous wastes that pose a serious threat to bio-existence. Most pharmaceutical formulations contain chemically-synthesized surfactants. The purpose of this work is to suggest an alternative source of surfactant which would also aid in ridding our environment of harmful wastes. Bacillus licheniformis B-4 strain isolated from a hydrocarbon dump site p...
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