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ANTIPROLIFERATIVE ACTIVITY OF THREE WILD GROWING SPECIES IN TUNISIA: NICOTIANA GLAUCA, ARTEMISIA CAMPESTRIS AND ASTRAGALUS GOMBO
Tunisian flora contains several wild plants with diverse therapeutic uses. As a contribution to the efforts to select natural sources of antitumor compounds, we investigated in this study the antiproliferative activity of several extracts of the Tunisian species: Astragalus gombo, Nicotiana glauca and Artemisia campestris. Dried aerial part (A. gombo and A. campestris) and leaves (N. glauca) were ...
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PHARMACOGNOSTIC STUDY OF ZIZIPHUS MAURITIANA LAM. (RHAMNACEAE)
Objective: To study the preliminary and pharmacognostic characteristics of Ziziphus mauritiana Lam., harvested in Côte d'Ivoire. Identify the drug by anatomy and histochemistry. Method: Macroscopic and microscopic study of the fresh and dry drug and determination of physicochemical parameters. Results: Tree, shrub or bush, 16 m long, 5 m or 4 m, Ziziphus mauritiana Lam. Has bending branches with ...
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ANTIMICROBIAL AND ANTIOXIDANT POTENCY OF DENDROPTHOE FALCATA LINN.
The World Health Organization survey indicated that about 70-80% of the world’s populations rely on non-conventional medicine, mainly of herbal sources, in their primary healthcare. Among them parasitic plants are well known, 20 different species are belonging to the genus Dendrophthoe falcate (Loranthaceae) found all over the world, seven of which are found in India. The hemiparasite, Dendropht...
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BIOACTIVE COMPOUND IDENTIFICATION, PHYTOCHEMICAL ESTIMATION, IN-VITRO ANTI-INFLAMMATORY AND ANTIOXIDANT ACTIVITY OF PUPALIA LAPPACEA
Pupalia lappacea Juss belongs to the family Amaranthaceae useful in the bone fracture treatment, antimalarial, pyrexia, wounds, cough, toothache and boils. The present investigation was aimed to identify the phytocompounds by GC-MS, investigate phytochemically and to screen anti-inflammatory and antioxidant property by in-vitro methods. Bioactive compounds were identified using GC- MS; functional ...
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BIOTECHNOLOGICAL APPROACH FOR MEDICINAL PLANT CONSERVATION AND ENHANCED PRODUCTION OF SECONDARY METABOLITES
Growing awareness and interest towards traditional health care system coupled with phenomenal increase in demand and trade of medicinal plant has caused severe threat to the very existence of medicinal plants, which can be gauged from the fact that a number of important medicinal plants are becoming threatened or extinct, and an increasing number of species are being substituted in herbal preparat...
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DETERMINATION OF ANTIOXIDANT ACTIVITY OF CROCUS SATIVUS IN ADJUVANT INDUCED ARTHRITIC MICE
Rheumatoid arthritis (RA) is a chronic systemic disease which results in pain, swelling, and stiffness in joints. It affects about 1% of the total world’s population. RA begins with an edematous thickening of the synovia which latter converts into inflammatory synovium called pannus which erodes the surrounding cartilage. Conventional therapy exists to overcome illness but prolonged uses of drug...
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INVESTIGATION ON NOVEL ROLE OF SOLANUM XANTHOCARPUM AND JUNIPERUS COMMUNIS EXTRACT AGAINST CCl4 INDUCED LIVER INJURY
Background: There are very less therapeutic and reliable liver protective drugs in modern medicine to prevent and treat the liver injury caused due to drugs. Traditionally Solanum xanthocarpum Schradt. (SX) and Wendl. and Juniperus communis Linn. (JC) have been used since long for their hepatoprotective effect. The current study was carried out to explore the hepatoprotective role of SX and JC aga...
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DETERMINATION OF MEXILETINE IN PHARMACEUTICAL PREPARATIONS BY LINEAR SWEEP VOLTAMMETRY
A simple and rapid method for the determination of mexiletine in pharmaceutical preparations was developed and validated using linear sweep voltammetry (LSV). The proposed method was based on electrochemical oxidation of mexiletine at a platinum electrode in an acetonitrile solution containing 0.1M LiCIO4. The well-defined an oxidation peak was observed at +1.11 V. The calibration curve was linear...
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ARBUSCULAR MYCORRHIZAL FUNGAL DIVERSITY AND ROOT COLONIZATION OF SOME MEDICINAL PLANTS RHIZOSPHERE SOIL OF VRIDDHACHALAM, TAMIL NADU.
The present study was to analyze the occurrence of mycorrhizal diversity in 20 medicinal plants of Vriddhachalam, Cuddalore District, Tamil Nadu and to explore for structures correlated to the possible functional position of the symbiosis. Arbuscular mycorrhizal fungal colonization ranged from 24-81%. The highest infection was found in Justicia gendarussa and lowest in Naregamia alata. AM fungal s...
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EVALAUTION OF ANTHELMINTIC ACTIVITY OF RICINUS COMMUNIS LINN. LEAVES BY USING DIFFERENT TYPES OF SOLVENT
Aqueous and ethanol ethyl acetate chloroform-methanol extracts from the leaves of Ricinus communis were investigated for their anthelmintic activity against Pheretima posthuma and three concentrations (50, 75 and 100 mg/ml) of each extract were studied for activity, in which paralysis and death time of the worm. Both the extract exhibited remarkable anthelminthic activity at all three concentratio...
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