EVALUATION OF IN VITRO ANTI CANCER ACTIVITY OF HYDROALCOHOLIC FLOWER EXTRACT OF BUTEA MONOSPERMA VAR. LUTEA
Butea monosperma var. lutea, a native of India, is commonly known as “Palash” and popularly known as “Flame of Forest.” Traditionally it has been found that flowers have antimicrobial, wound healing, antifungal, antidiarrhoeal, hypoglycemic, hepatoprotective, antioxidant, anthelmintic, anti-convulsive, antistress, antidiabetic, anti-inflammatory activity. In the present study, crude hydroa...
THE STUDY EFFECT OF HYDRO-ALCOHOLIC EXTRACT OF JAPANESE PERSIMMON FRUIT ON FORMALIN-INDUCED INFLAMMATION IN THE RAT
Acute and chronic inflammation is the most important issue in the field of health. Also, due to the side effects of synthetic drugs, herbal products are widely used in the control of inflammation. In this study was investigated the effect of a hydro-alcoholic extract of Japanese persimmon fruit on the formalin-induced inflammation in the rat paw. 30 male Wistar rats were divided into 5 groups: neg...
PRELIMINARY PHYTOCHEMICAL SCREENING OF TWO MEDICINAL PLANTS -SOLANUM NIGRUM LINN. AND LEUCAS ASPERA (WILLD.) LINN.
The medicinal plants are useful for healing, as well as, for curing of human diseases because of the presence of phytochemical constituents. Phytochemicals are naturally occurring in the medicinal plants, leaves, vegetables, and roots that have defense mechanism and protect from various diseases. The leaves of Solanum are used to treat mouth ulcers that happen during winter periods in Tamil Nadu. ...
IN SILICO PREDICTION OF RIBOSWITCH AS A POTENTIAL DRUG TARGET AND DESIGN OF ITS OPTIMAL INHIBITORS AND PHARMACOPHORE FOR BACILLUS CEREUS
Bacillus cereus is a gram-positive, rod-shaped, motile, beta hemolytic bacteria. These bacteria cause foodborne illness, severe nausea, vomiting, diarrhea, and keratitis. Foodborne illness caused by Bacillus cereus occurs because of the bacterial endospores survival in improperly cooked food. The bacteria produce enterotoxins having high resistance against heat and acids, and they cause the diarrh...
THE MECHANISTIC APPROACH OF THE PROPYLENE GLYCOL AS A CO-SURFACTANT THROUGH “SIX MEMBER CYCLIC HYDROGEN BONDING SYSTEM” FOR THE STABLE AND FLEXIBLE MICROEMULSION DRUG CARRIER
The improvisation of any system has been a challenging task for the scientist in the field of drug delivery. In pursuit of the stable carrier system, here the microemulsion or other meta-state like liquid crystal phase with the specific mechanism, i.e., “six-member stable cyclic system” is highlighted and critically evaluated. The system with co-surfactant (propylene glycol) is examined and co...
COMPARATIVE PHARMACOGNOSY AND PHYTOCHEMICAL ANALYSIS OF MEDICINAL PLANTS WITH ANTIDIABETIC ACTIVITY (PTEROCARPUS MARSUPIUM ROXB., AZADIRACHTA INDICA A. JUSS., TRICHOSANTHES DIOICA ROXB., SYZYGIUM CUMINI LINN. AND MOMORDICA CHARANTIA LINN.)
Diabetes mellitus is becoming a threat to the world’s population as it is spreading like an epidemic. Pterocarpus marsupium Roxb., Azadirachta indica A. Juss., Trichosanthes dioica Roxb., S. cumini Linn. and M. charantia Linn. are well known for their properties in the management of diabetes. In recent times, there has been significant growth in the field of Ayurvedic medicines because of their ...
PRELIMINARY TISSUE CULTURE STUDY OF THE CALLUS PRODUCED FROM THE AERIAL PARTS OF ANTIGONON LEPTOPUS (HOOK & ARN)
Antigonon leptopus Hook & Arn (family Polygonaceae), also called: Chain of love, Queen’s Wreath and Mexican creeper is a fast-growing vine with stems reaching up to 20 feet long. It has heart-shaped, green leaves climbing by tendrils which wrap around many types of supports. It is native to Mexico and commonly found in tropical Asia, Africa, the Caribbean, and the Americas. It possesses anti...
ANABOLIC EFFECT ON BONE FORMATION OF NANO ENCAPSULATED VOLATILE OIL OF RUTA GRAVEOLENS LEAVES IN LARVAL ZEBRAFISH MODEL
Aim: The present research aims to screen anabolic activity on bone formation and bone density in normal and Teriparatide (Rh PTH biosynthetic human parathyroid hormone 1-34) induced inhibition of osteogenesis in zebrafish larval model to alleviate osteoporosis and other bone and joint disease or disorders of the Nano encapsulated essential oil isolated from the Ruta graveolens (NELVORG) Family: Ru...
The objective of the study was to formulate and evaluate the antioxidant activity and the wound healing effect of the Punica granatum peel extracts formulation. Tannins, alkaloids, flavonoids, proteins, and phenols were present in the ethanolic extract, which is further formulated in a gel formulation. Seven herbal gel formulations were prepared using 1.5% of the gelling agent’s carbopol 940 (F1...
PHARMACOGNOSTIC AND HPTLC CHARACTERIZATION OF KIRATATIKTA, SWERTIA CHIRAYITA (ROXB. EX FLEM.) KARSTEN
Background: Swertia chirayita (Roxb. ex Flem.) Karsten known as Kiratatikta in Ayurveda, the Indian indigenous health system, is used for various ailments like liver disorders, diabetes, fever, worm infestation, and others. Due to huge demand and non-availability, other Swertia species and other herbs are used as substitutes/adulterants for Swertia chirayita (Roxb. ex Flem.) Karsten. Hence, the pr...