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CHEMICAL COMPOSITION AND ANTIFUNGAL ACTIVITY OF ESSENTIAL OILS FROM AERIAL PARTS OF MENTHA PIPERITA AND MENTHA ARVENSIS
The present study deals with the chemistry and antifungal activity of essential oil (EO) of two species of Mentha viz. Mentha piperita and Mentha arvensis which was extracted using Clevenger-type apparatus. The percent yield of EO of M. arvensis (2.8%) was found higher than M. piperita (2.1%). Compositional analysis of M. piperita and M. arvensis EO oil by GC-MS revealed the presence of 51 and 35 ...
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ASSESSMENT OF MALATHION INDUCED TOXICITY IN DATTAPHRYNUS MELANOSTICTUS TADPOLES: A BIOCHEMICAL INVESTIGATION
Environmental pollutants apart from other factors like habitat loss and interventions of invasive species, is regarded as a likely cause towards a worldwide decline in amphibian population. The present study attempts to elucidate the toxicity of commercially formulated malathion (MAT) by investigating biochemical aspects in Dattaphrynus melanostictus tadpoles. Three sublethal concentrations of MAT...
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MOLECULAR BEACONS: FUNDAMENTAL ASPECTS AND APPLICATIONS
Molecular Beacons (MBs) are DNA hairpins that are widely used as fluorescent probes. The inherent signal transduction mechanism let them differentiate between target and non-target oligonucleotides that differ even on a single base. The stem-loop structure consists of donor and acceptor moieties conjugated to both ends thus lying nearby, which leads to FRET. On hybridization to target sequences th...
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ANTIFUNGAL STUDY OF CHEMICAL CONSTITUENTS ISOLATED FROM PIPER CALDENSE C. D.C.
An intensive phytochemical study of the two parts of the Piper caldense plant brings the isolation of secondary metabolites, generated by shikimate and the mevalonate pathways. Using chromatographic techniques, the ethanolic extract of leaves afforded two pheophytyns, the pheophytin (1), 151-hydroxy-pophyrinlactone a (2), a mixture of the β-sitosterol and stigmasterol steroids (3-4). Four derivat...
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DEVELOPMENT AND CHARACTERIZATION OF SOYA PHOSPHATIDYLCHOLINE COMPLEX OF COUMESTANS FROM ECLIPTA ALBA FOR THE EFFECTIVE MANAGEMENT OF HEPATOTOXICITY
It is known that Eclipta alba Hassk. (Family: Compositae) contains coumestans (Wedelolactone and dimethyl wedelolactone) are used in liver disorders. The objective of the present investigation was to develop a novel formulation of these coumestans in combination with the soya phosphatidylcholine (PC), to overcome the limitation of absorption and to investigate the protective effect of the coumesta...
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CHEMICAL COMPOSITION OF FIXED OIL FROM THE SEEDS OF SANTALUM RUBRUM BY GC-MS
Santalum rubrum is medicinally important plant belonging to the family of Santalaceae. It has been used extensively by Ayurvedic practitioner and is also reported to contain anthraquinones and flavonoids, these constituents are well documented to possess anti-inflammatory activity. The fatty acid compositions of the petroleum ether extract of seeds of this plant were determined by Gas Chromatograp...
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ANTIANXIETY, ANTICONVULSANT, MYORELAXANT AND HYPNOTIC EFFECT OF POLYHERBAL EXTRACTS ON RODENTS
The research in alternative medicine and the need for the plant-based medicines that affect the ‘mind’ is developing day to day. The aim of the present study was to explore Leptadenia reticulata (roots), Mimusops elengi (bark) and Evolvulus alsinoides (Whole plant) using different animal models (conditional avoidance response, hole board test, open field test), anticonvulsant (MES induced conv...
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PHARMACOGNOSTICAL AND PRELIMINARY PHYTOCHEMICAL SCREENING OF THE ROOT TUBERS OF CURCULIGO ORCHIOIDES GAERTN.
India is well known as the emporium of medicinal plants harboring many plants of medicinal importance, of which Curculios orchioides is one that has been reported to possess medicinal importance for the treatment of various diseases traditionally as well as scientifically. An attempt was made herein to undertake a detailed pharmacognostical and preliminary phytochemical investigation of the root t...
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HERBAL REMEDY FOR WOUND MANAGEMENT: A REVIEW
Since from prehistoric times the practice of herbal medicine has existed as the primary form of medicine. India is one of leading bio-diversity center with the presence of over 50, 000 different plant species. Many plants are unexplored though they were used from ancient times in traditional system of medicine. At the same time, several plants activity was proven scientifically, and its resurgence...
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EVALUATION OF ANTI-DIABETIC ACTIVITY ON n-BUTANOL FRACTION OF LEAF METHANOLIC EXTRACT OF CURCULIGO ORCHIOIDES (AMARYLLIDACAE) IN STREPTOZOTOCIN INDUCED DIABETIC RATS
The aim of the present study to evaluate the anti-diabetic activity of methanolic extract n-butanol fraction of Curculigo orchioides (Amaryllidaceae) against in streptozotocin-induced diabetic rats. Fractions were administrated orally at 200 mg/kg and 100 mg/kg for 3weeks. The effects were compared with an oral dose of 10 mg/kg of glibenclamide. Blood glucose levels are a determination by GOD-POD ...
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