Volume 1 (2014) - Issue 5, May
PLANT PROFILE, PHYTOCHEMISTRY AND PHARMACOLOGY OF BAUHINIA VARIEGATA LINN. (KACHNAR): AN-OVERVIEW
Bauhinia Variegata Linn. is a widely used medicinal plant distributed in the tropical regions throughout the world. Its various part i.e. flowers, flower buds, stem, roots, stem bark, seeds, leaves have been used since ancient times for the treatment of a large range of diseases such as dysentery, diarrhoea, haemorrhoids, piles, oedema, laxative, anthelmintic, astringent, antileprotic, wound heali...
NITRIC OXIDE AS A TARGET FOR HYPERTENSION MANAGEMENT: A REVIEW ARTICLE
High blood pressure is well-established as a leading cause of stroke, ischemic heart disease, and cardiovascular disease. Globally cardiovascular disease accounts for approximately 17 million deaths a year, nearly one third of the total. A number of pharmaceutical agents are available for initial treatment of high BP. These include older molecules such as diuretics and beta-blocking agents, and ne...
PROFILING OF THE CHEMICAL COMPOUNDS IN ETHYL ACETATE EXTRACTS OF LAUNAEA CORNUTA ASTERACEAE BY GC-MS
Launea cornuta Asteraceae is widely used among African communities for its medicinal and nutritional values and livestock fodder. Traditionally, it is used by Kenyan communities to manage diabetes mellitus, syphilis, and stomachache, among many other diseases. The current study profiled the organic chemical compounds in the ethyl acetate extracts of L. cornuta. Chemical compounds were identified u...
ANALGESIC AND ANTI-INFLAMMATORY ACTIVITIES OF VITEX NEGUNDO (LEAVES) EXTRACT
Aims: Analgesic and anti-inflammatory effects of Vitex negundo leaves extract (VNE) were evaluated in the animal models. The VNE was evaluated for the phytochemical analysis. Settings and Design: Factorial design was used for the experimental models. Methods and Material: The analgesic effects at graded doses of VNE (40-320 mg/kg, p.o.) were evaluated in mice against acetic acid-induced writhing (...
MEDICINAL POTENTIAL OF PHYLLANTHUS EMBLICA (LINN.) FRUITS EXTRACTS: BIOLOGICAL AND PHARMACOLOGICAL ACTIVITIES
The objective of the present study was to investigate the scientific basis of the traditional use of the fruit of Phyllanthus emblica (Linn.). The selected pharmacological investigations are antimicrobial screening, analgesic activity, antidiarrheal activity screening and the brine shrimp lethality test for cytotoxic activity. Phytochemical analysis of ethanolic fruits extracts Phyllanthus emblica...
DETERMINATION OF ANTIOXIDANT ACTIVITY OF CROCUS SATIVUS IN ADJUVANT INDUCED ARTHRITIC MICE
Rheumatoid arthritis (RA) is a chronic systemic disease which results in pain, swelling, and stiffness in joints. It affects about 1% of the total world’s population. RA begins with an edematous thickening of the synovia which latter converts into inflammatory synovium called pannus which erodes the surrounding cartilage. Conventional therapy exists to overcome illness but prolonged uses of drug...
PHYTOCHEMICAL ANALYSIS AND ANTIOXIDANT PROPERTY OF TRIGONELLA FOENUM, ZEA MAYS AND ORYZA SATIVA
Plants have been used for centuries as a remedy for human diseases because they contain phytochemical components of therapeutic values. The whole plant of the Trigonella foenum, Zea mays and Oryza sativa were selected for in this study to find out the phytochemicals and antioxidant property. Phytochemicals were extracted using various solvents such as Hexane, Ethyl acetate, and ethanol. Screening ...
HEPATOPROTECTIVE ACTIVITY OF ETHANOLIC EXTRACT FROM THE STEM BARK OF SYNEDRELLA NODIFLORA ON CARBON TETRACHLORIDE INDUCED HEPATOTOXICITY IN SWISS ALBINO RATS
The ethanol extracts of stem bark of Synedrella nodiflora belonging to the family of Asteraceae was studied for hepatoprotective activity against Swiss Albino Rats with liver damage induced by carbon tetrachloride (CCl4). It was found that the ethanol extract of Synedrella nodiflora at a dose of 250 mg/kg body weight exhibited significant protective effect by lowering the serum level of alanine am...
PHARMACOGNOSTICAL STANDARDIZATION OF KAILASPATI
Pharmacognostical parameters for the leaves including petiole of Kailaspati was studied with the aim of drawing the Pharmacognostical standards for this species. Macroscopical and microscopical characters of leaves and petiole, powder characteristics studies, fluorescence studies and thin layer chromatographic studies of the leaves powder included. The study also deals with the preliminary phytoch...