Posted by admin on Jun 30, 2025 in |
To perform phytochemical screening, estimate total phenolics and total flavonoid content of hydro alcoholic extract of dried leaves of Portulaca grandiflora Hook. The shade- dried leaves of P. grandiflora (100 g) were extracted exhaustively by Soxhlet with hydro- alcohol. The conc. hydro-alcoholic extract were further studied to quantitative determination, GC-MS and HPTLC to identify and characterize the chemical compound present in the crude extract. The phenolic content present in hydro-alcoholic leaf extract was found to be 1.57µg/ml (µg of Gallic acid/mg of extract) and flavonoid content was found to be 2.73µg/ml (µg of Rutin/mg of extract). Phytochemical analysis of hydroalcoholic extract showed presence of major classes of phytochemicals. High performance – thin layer chromatography results revealed the mobile phase of ethyl acetate: formic acid: glacial acetic acid: water (10:0.5:0.5:1.3), the fluorescent band under (254 nmand366 nm) at Rf 0.21 was identified, and the marker chemical rutin was measured. Gas chromatography – mass spectroscopy results showed the presence of 27 phytoconstituents including phenolic acids, ketones, flavonoids, carbohydrates, and hydrocarbons. The...
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Posted by admin on Jun 30, 2025 in |
This study evaluated the antibacterial activity of eight commercially available toothpaste samples (P1–P8) and a standard antibiotic control (Tetracycline) against three oral bacterial isolates (C2, C3, C4) and Escherichia coli using the well diffusion method. Zones of inhibition were measured to assess antimicrobial efficacy. Among all samples, P1 demonstrated the highest activity, with inhibition zones surpassing those of the antibiotic control for several strains. P8 exhibited consistent activity across all bacteria, while P2 was selectively effective against C3. In contrast, P4, P6, and P7 showed no activity against E. coli. Notably, E. coli resistance to several formulations underscores the need for rigorous post– brushing rinsing to minimize potential impacts on gut microbiota. The results affirm that antibacterial efficacy varies widely among commercial toothpaste brands, likely due to differences in formulation and active components. This study highlights the superior antibacterial action of certain commercial toothpastes compared to antibiotics and also underscores the importance of product–specific evaluation for effective oral health...
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Posted by admin on Jun 30, 2025 in |
Background: Colocasia gigantea is a large, stemless, tuberous, frost-tender perennial of the arum family, which typically grows tall and wide. It is found abundantly in tropical countries, and in Southeast Asia. Methodology and Results: Phytochemical analysis using gas chromatography and acute toxicity testing was done on methanolic leaf extract of Colocasia gigantea. The adult male wistar rats used for acute toxicity testing were 13 in number. The results showed that at 5000mg/kg, of administration of methanolic leaf extract Colocasia gigantean, no death occurred among the wistar rats used for the study. Phytochemical analysis results on methanolic leaf extract of Colocasia gigantea showed the presence of flavonoids (flavon – 3-ol and flavone), alkaloids, tannins, nobiletin, artemetin. Conclusion: Methanolic leaf extract of Colocasia gigantea contains substances of significant medicinal values and acute administration of methanolic leaf extract is relatively...
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Posted by admin on Jun 30, 2025 in |
Plants create bioactive substances called phytochemicals to defend themselves. Consuming phytochemicals including carotenoids, polyphenols, isoprenoids, phytosterols, saponins, dietary Fibers, polysaccharides, etc. has been linked to certain health outcomes, according to recent scientific research. This article lists a few of these well-known fruits, such as Persea americana, Selenicereus undatus, Morus, Psidium guajava, Mallus domestica, and Vaccinium macrocarpon, that may offer new sources of health-promoting substances. Additionally, this web page lists a few of these popular fruits that could deliver fresh supplies of substances that enhance health. A diet rich in fruits has been linked to a lower risk of noncommunicable diseases because they contain a variety of compounds that, in addition to vitamins and minerals, offer health-protective qualities. Many have therefore chosen to enhance their overall standard of life through increasing their fruit intake, taking dietary supplements or nutraceuticals, or using nutritional therapy or phytotherapy in place of prescription medications. The development of specific horticulture models for the production of nutritional fruits may offer an interesting opportunity to obtain an...
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Posted by admin on Jun 30, 2024 in |
Since ancient times, Baccaurea species have held economic value for the indigenous peoples of the Old-World Tropics, used for both their edible fruits and medicinal properties. Among these, Baccaurea motleyana, commonly known as Rambai, is notable for its diverse uses and is widely cultivated across Southeast Asia. This study explores the botanical characteristics, traditional applications, and pharmacological potential of B. motleyana. Rambai thrives in tropical rainforests and diverse soil types, growing up to 25 meters tall. The fruit is consumed fresh, while various plant parts are used medicinally to treat ailments such as constipation, eye swelling, arthritis, and abdominal pain. Notably, the bark is used to prevent postpartum hemorrhage, and the leaves treat menstrual disorders. Nutritionally, Rambai fruits are rich in vitamins and minerals, including vitamin C and potassium, and exhibit antioxidant and antimicrobial properties due to their high phenolic content. Phytochemical screening reveals the presence of alkaloids, flavonoids, saponins, triterpenoids, and tannins, contributing to its medicinal properties. Pharmacological studies highlight its antioxidant, antimicrobial, antidiabetic, and anticancer activities. For...
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