Posted by admin on Jun 30, 2026 in |
Exposure to ultraviolet (UV) radiation from sunlight is a major cause of skin damage, premature aging, and skin cancer. Sunscreen creams are widely used to protect the skin from harmful UV rays; however, the long-term use of synthetic sunscreens may cause skin irritation and other adverse effects. Therefore, there is growing interest in the development of herbal sunscreen formulations using natural ingredients. The present study focuses on the formulation, characterization, and evaluation of a herbal sunscreen cream using sesame oil as the main active ingredient. Sesame oil is rich in natural antioxidants such as sesamol and sesamin, which exhibit UV-absorbing and free-radical scavenging properties. In this study, an oil-in-water type herbal sunscreen cream was formulated using sesame oil along with suitable excipients such as emulsifiers, preservatives, and stabilizers. The prepared formulation was subjected to characterization tests including physical appearance, pH, viscosity, spreadability, homogeneity, and type of emulsion to ensure formulation quality and stability. The evaluation of the herbal sunscreen cream was carried out to assess its sun-protective and safety...
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Posted by admin on Jun 30, 2026 in |
Asthma is a chronic respiratory disorder characterized by airway inflammation, bronchoconstriction, and excessive mucus production. This study evaluated the anti-asthmatic, antioxidant, and anti-inflammatory potential of the methanolic fruit extract of Morinda citrifolia (noni), a medicinal plant widely used in traditional herbal medicine. Dried fruits were shade-dried, powdered, and extracted with methanol using a Soxhlet apparatus. The extract was investigated using in-vivo models including histamine aerosol-induced bronchoconstriction, milk-induced leukocytosis, and eosinophilia to assess anti-asthmatic activity. Antioxidant activity was determined by hydrogen peroxide scavenging and reducing power assays, while anti-inflammatory activity was evaluated through protein denaturation inhibition and red blood cell membrane stabilization methods. The extract was administered at doses of 200 mg/kg and 400 mg/kg. Results demonstrated significant bronchodilatory activity with reduced leukocyte and eosinophil counts, indicating notable anti-asthmatic effects. The extract also exhibited considerable free radical scavenging capacity and membrane stabilizing activity, confirming its antioxidant and anti-inflammatory properties. These pharmacological activities may be attributed to the presence of bioactive phytoconstituents such as flavonoids, alkaloids, glycosides, saponins, and tannins. The...
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Posted by admin on Jun 30, 2026 in |
Clerodendrum inerme (L.) [syn. Volkameria inermis] is a traditional medicinal plant used to treat against viral, neurological, metabolic, and inflammatory illnesses. It had not had a comprehensive synthesis of its traditional knowledge and up to date molecular pharmacology even after a number of experimental research. Concentrating on mechanistic data, the present research tries critically to evaluate and revise the pharmacognostic characters, phytochemical structure, and pharmacological action of C. inerme. Relevant materials in the electronic databases, including PUBMED, SCOPUS, and GOOGLE SCHOLAR were carefully searched to obtain literature published until 2025. According to the information now available, the plant is abundant in bioactive secondary metabolites that are linked to a variety of biological activities, including flavonoids, diterpenoids, phenolics, and iridoid glycosides. Through the regulation of oxidative stress, inflammatory signalling pathways, neurotransmitter systems, and enzyme activity, pharmacological investigations show notable anti-inflammatory, antioxidant, neuroprotective, antibacterial, antidiabetic, and hepatoprotective effects. However, translational interpretation is constrained by inconsistent experimental design, a lack of standardised extracts, and a paucity of toxicological and clinical data. The...
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Posted by admin on Jun 30, 2026 in |
Obesity and overweight is excessive or abnormal accumulation of fat in body that presents a risk to health. Overweight and obesity have reached epidemic proportions, with over four million individuals dying every year as a result of their condition. Different approaches comprising biological sources, different drug therapy, have been used in obesity treatment; though, these unoriginal selections linger unproductive and carry risks of adverse drug reaction. Hence, treatment with high efficacy and specificity is the need of the hour. Novel drug delivery system use herbal medicines and chemical entities to develop healing efficacy, target oriented through herbal approach for equilibrium, controlled release of antiobesity agents. In this review, we provide insights into current treatments for obesity with a focus on recent developments of herbal polymeric carriers for improved antiobesity drug...
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Posted by admin on Jun 30, 2026 in |
This study aims at valorizing the leaves of Hymenocardia acida Tul., a medicinal plant traditionally used in the Republic of Congo and other African countries, for healing cough and respiratory infections. The aqueous extract, prepared by decoction, showed a low acute toxicity in mice (LD50 > 5000 mg/kg). The phytochemical screening revealed the presence of flavonoids, condensed tannins, saponins, mucilages, reducing sugars, and anthraquinones. The oral administration of the extract at 200 mg/kg and 500 mg/kg significantly inhibited ammonia-induced cough in guinea pigs, with a prolonged reaction latency and a reduction of post-exposure cough bouts, comparable to the effect of dextromethorphan (0.5 mg/kg). Conversely, no significant effects were observed on cigarette smoke-induced cough. The extract also exhibited an in vitro antibacterial activity against a clindamycin-resistant strain of staphylococcus aureus, at concentrations of 1% and 10%, but no activity was observed against Escherichia coli. These findings validate the traditional use of Hymenocardia acida Tul. and highlight its natural antitussive and antibacterial...
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