Posted by admin on Feb 28, 2021 in |
Botanicals and herbal preparations for medicinal usage contain various types of bioactive compounds. The focus of this paper is on the analysis of bioactive compounds present in the Pisonea aculeata Linn. having anticancer activity involving the applications of chromatographic techniques such as TLC and column chromatography, Spectrophotometric techniques such as UV, 1H-NMR, 13C-NMR, and EIMS spectral studies. The present investigation was carried out by fractionating the Methanolic extract of Pisonia aculeata (MPA) using benzene, diethyl ether, and ethyl acetate. Ethyl acetate fraction on concentration subjected to separation and purification on column chromatography. Fractions were collected & homogeneity was examined on TLC. A Fraction 77-90 on concentration yielded a pure yellowish homogeneous solid and gave dark green coloration with neutral ferric chloride and violet coloration with Molish’s reagent. In order to find out the nature of the glycoside, compound I was subjected to acid hydrolysis. The basic flavonoid structure of the compound studied by recording UV spectrophotometer showed an intense UV maxima at 273 nm (band II) and 329 nm...
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Posted by admin on Feb 28, 2021 in |
The study investigated the antibacterial properties of the water and ethanolic extracts of the seed of alligator pepper on two bacterial species, Salmonella typhimurium and Escherichia coli, which are known human pathogens. The phytochemicals (alkaloids, flavonoids, saponins, tannins, glycosides, and phytates) in the seed extracts were estimated. The organisms were obtained from the microbiology laboratory of Federal Medical Centre (FMC), Yenagoa, Bayelsa State. The antibacterial activity of the different concentrations of the extract (5 mgml-1, 10 mgml-1, 20 mgml-1, 30 mgml-1 and 50 mgml-1) were evaluated against the test organisms. Also, the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were determined. Results showed that both the water and ethanolic extracts of the seed of the plant had inhibitory effects on the test organisms. Statistical analysis (ANOVA) demonstrated no significant difference (P=0.05) in the inhibitory effects of the extracts and the control on the organisms. It is concluded that both the water and ethanolic extracts of the seed have antibacterial properties and could be used in the treatment...
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Posted by admin on Feb 28, 2021 in |
Arjuna is a well-known drug in Ayurveda. It is mainly used for heart disease, Obesity, and hemorrhagic disorders. It is used in various dosage form in Ayurveda such as powder, milk-based decoction, alcoholic fermented liquids, tablets, etc. Its bark is used for therapeutic purposes. Although it is widely available all over India, most of the time it is procured from the market; hence it needs to assure the quality of marketed Arjuna for standard quality formulations. Ayurvedic pharmacopeia of India (API) has given a monograph of Arjuna bark. So in this study, authentication, organoleptic, macroscopic, microscopic, and physicochemical analysis of a market sample of Arjuna was carried out. Organoleptic, macroscopic, microscopic studies have shown relatively similar characteristics as per standard. In physicochemical analysis, foreign (0.06%) matter was within normal range. Ash value (27.77%) was higher whereas acid insoluble ash (1.08%) almost matches with standard value, which shows more inorganic contents in Arjuna. Acid insoluble ash was nearly the same as a standard value. Water soluble extractive value (19.98 %)...
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Posted by admin on Feb 28, 2021 in |
Essential oils are obtained from plant material. The essence or aromas of plants are due to volatile or essential oils, many of which have been valued since antiquity for their characteristic odours. In this study, qualitative and quantitative analyses of the essential oil compositions in cinnamon oil were made by using gas chromatography-mass spectrometry (GC-MS). In this analysis, the main constituents of cinnamonoil are cinnamal (63.59%), eugenol (8.32%), cinnamyl acetate (7.48%), caryophyllene (6.88%), linalool (6.31%) and eucalyptol (2.57%). These six components account for 95.15% of the total relative content of the cinnamon oil. This research also demonstrated that the cinnamonoil is rich in cinnamal, eugenol, cinnamyl acetate, caryophyllene and linalool could be a good source for these...
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Posted by admin on Jan 31, 2021 in |
Propolis is a natural material that can be found in bee honey. It has many medical uses due to its antibacterial activity. This study aimed to estimate the antibacterial efficacy of three propolis extracts using three different solvents (Ethanol, Methanol, and Ethyl Acetate). We experienced the three extracts on four different strains of bacteria (Klebsiella pneumonia, E. coli, Pseudomonas aruginosa & Staphylococcus aureus). The results indicated that all the studied propolis extractions do not have any efficacy on Klebsiella neither on E. coli. The methanolic extract has the greatest effect on Staphylo-coccus aureus as well as on Pseudomonas aruginosa in contrast to ethanolic and ethyl acetate extracts, which has no efficacy on any of the studied bacterial...
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