Posted by admin on Jan 31, 2021 in |
Propolis is a natural material that can be found in bee honey. It has many medical uses due to its antibacterial activity. This study aimed to estimate the antibacterial efficacy of three propolis extracts using three different solvents (Ethanol, Methanol, and Ethyl Acetate). We experienced the three extracts on four different strains of bacteria (Klebsiella pneumonia, E. coli, Pseudomonas aruginosa & Staphylococcus aureus). The results indicated that all the studied propolis extractions do not have any efficacy on Klebsiella neither on E. coli. The methanolic extract has the greatest effect on Staphylo-coccus aureus as well as on Pseudomonas aruginosa in contrast to ethanolic and ethyl acetate extracts, which has no efficacy on any of the studied bacterial...
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Posted by admin on Jan 31, 2021 in |
All information about the herbal drug, including all its organoleptic characters, phytoconstituents, pharmacological actions, and its standardization in respect to various parameters, is required before developing an herbal drug formulation. Butea monosperma (Lam.) is commonly known as the Flame of the forest, belongs to the family Fabaceae. Commonly Butea monosperma is used as tonic, astringent, aphrodisiac, and diuretics. We are doing this work because it was thought worthwhile to explore this most functional plant based on this standardization parameter. The objective of the work is to study pharmacognostic and physicochemical characteristics of the root of Butea monosperma Fresh and dried root; root powder was studied for its morphology, microscopy, physicochemical, phytochemical characteristics, and other WHO-recommended methods for standardization. The root of Butea monosperma was observed to be brown in color and irregular in shape with a rough surface. The root has a characteristic odour and faint taste. Microscopy revealed the presence of cork cells; Medullary rays distinct parenchymatous cells narrow in the xylem region and wider in the phloem...
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Posted by admin on Jan 31, 2021 in |
Nymphaeaceae is a perennial herbaceous plant with a creeping rhizome that lives in calm waters at the edge of the lake or in the slowly flowing water channel. There are two species, Nymphaea alba (white lotus) and Nupharlutea (yellow lily), in Turkey, of which N. alba is common found in the Mediterranean region. In the present study, N. alba was used to discover novel alternative additives for industrial applications. The leaves of N. alba were collected from the Hatay region and dried in room conditions and pulverized, and then powdered. The powdery samples were examined by ICP-MS, GC/MS, LC/MS/MS, SEM and EDX, and XRD. Essential and free fatty acids analysis was conducted by GC/MS and found to be 1.75%. Minerals compounds were scrutinized by ICP/MS, results of minerals were found as Na 12864, Mg 1864.14, K 5144.35, Ca 8262.34 ppm. In addition, the alpha-tocopherol (E vitamin) analysis was examined by LC/MS/MS were found as 5.6 ± 0.4 mg / 100 g. The present analysis showed that N. alba extracts...
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Posted by admin on Dec 31, 2020 in |
The aim of this study was to evaluate antisecretory and antioxidant activities of the leaves aqueous extract of Boscia angustifolia (LAEBA) on gastric ulcers induced in male rats. LAEBA at the doses of 125, 250, and 500 mg/kg were tested on three models of gastric ulcers, namely: pylorus ligation, pylorus ligation + histamine, and pylorus ligation + carbamylcholine. Some parameters of oxidative stress (malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT), and reduced glutathione (GSH)) were evaluated in stomach’s homogenates. The qualitative phytochemical screening of LAEBA was carried out. Antisecretory screening showed that LAEBA at 500 mg/kg significantly decreased (p<0.01) gastric acidity (8.06 mEq/l) compared to the negative control (14.07 mEq/l), with a significant reduction (p<0.001) of gastric volume (1.30 ml) compared to the negative control (5.12 ml), as well as a reduction of pepsin activity (64.64%). These variations were similar to pylorus ligation + histamine and pylorus ligation + carbamylcholine models. LAEBA at all the doses induced a significant reduction (p< 0.05) of ulcerated surface correlated with an increase...
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Posted by admin on Dec 31, 2020 in |
Genus Memecylon belonging to the family Melastomataceae is a large shrub or a small tree native to Western Ghats of India. Memecylon species are reported to show various biological activities and are also used as medication in herpes virus infection. RNases and proteases are involved in the replication of herpes simplex virus (HSV). The present study was taken up to screen RNase and protease (trypsin and thrombin) inhibitors in different solvent extracts of Memecylon species viz., M. umbellatum, M. malabaricum, M. wightii, M. edule and M. talbotianium. The methanol extract of the leaves of Memecylon species was observed to strongly inhibit RNase, trypsin, and thrombin functions in a dose-dependent manner. The percent inhibition of RNase activity ranged from 53-84% in 50 ug/mL of plant extracts. The highest inhibition was observed in M. malabaricum and M. wightii for RNase. Similarly, for trypsin the percent inhibition ranged from 55-68% in 1 mg/mL of plant extracts. Highest inhibition was observed in M. malabaricum, M. wightii, and M. talbotianium. For thrombin the percent...
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