Posted by admin on Feb 28, 2023 in |
The present study aimed to investigate the essential oil of Solenostemon monostachyus aerial part extract and its antioxidant and phytochemical potency. The essential oil of S. monostachyus aerial part was obtained by hydrodistillation using Clevenger-type apparatus, and the aqueous extract by infusion. Gas chromatography-mass spectrometry analysis of the essential oil gave twenty-two compounds as the major constituents with their retention factor. A total of forty-three compounds were identified of which limonene (55.40 %) and neral (10.39%) were found as major compounds followed by trans-verbenol (6.43%) and decanal (3.25%). The aqueous extract’s phytochemical analysis revealed terpenes, alkaloids, sterols, tannins, reducing sugar, flavonoids, saponins, and anthraquinones. HPLC analysis gave sixteen peaks, including tannins, caffeic acid, rutin, ferulic acid, morin, and apigenin. S. monostachyus exhibited antioxidant activity from the first dilution at 20 mg/mL up to the ninth dilution at 0.08 mg/mL in 2-fold dilutions signifying the presence of antioxidant compounds at those concentrations. Therefore, the results showed that the aqueous and hydroalcoholic extract of Solenostemon monostachyus exhibited antioxidant...
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Posted by admin on Jan 31, 2023 in |
The expansion of research on finding herbal sources for producing new effective and safe medicinal herbal remedies is an urgent pharmacy task. One of the ways to increase the amount of herbal medicinal preparations is a broad study of the pharmacological action of non-pharmacopoeial medicinal plants used in folk medicine. One of these plants is Black root officinalis (Cynoglossum officinale), which grows wild in the European part of Russia, Siberia, Central Asia, and the Caucasus, including North Ossetia, but does not form significant thickets. Today Cynoglossum officinale is used mainly in folk medicine as an anti-inflammatory, analgesic, sedative, and expectorant. When applied externally, Cynoglossum exhibits antipruritic properties and is capable of tissue regeneration. Therefore, the pharmacognostic study for further research on pharmacological effects on the human body is quite...
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Posted by admin on Dec 1, 2022 in |
Objective: This study aim’s to deal with the in vitro anticancer activity of flowers of Couroupita guianensis (family: Lecythidaceae) against B16F10 (skin cancer cell line). Materials and Methods: MTT assay for flowers of Couroupita guianensis against B16F10 (Skin Cancer cell line) is conducted. Results: At the Concentration 44.44 µg/ml, the methanolic flower extract of Couroupita guianensis showed good percent inhibition of B16F10 (Skin Cancer cell line) as compared to the standard drug. Conclusion: The present attempt provides information that may generate researchers’ interest in exploring such natural...
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Posted by admin on Dec 1, 2022 in |
Caesalpinia sappan L. is a member of the Caesalpiniaceae family. It originated from India through Myanmar and Thailand to peninsular Malaysia to Indochina and south china. It is also called Brazilin. The heartwood of Caesalpinia sappan contains water soluble properties that color to transform into the red. When oxidation process occurred. The chemical constituents investigation of sappan wood resulted that it has phenolic components, including one xanthine, one coumarin, three chalcone, 2 flavones, three homoisoflavonoid and Brazilin. The traditional Chinese medicine brazilin is used to treat increased blood circulation, promote menstruation, and exhibit analgesic property. The article aims to review the pharmacognostic study of Caesalpinia sappan and explore its pharmacological properties such as antioxidant activity, antibacterial activity, antiacne activity, anti-inflammatory activity, hepatic-protective, anticancer activity, and larvicidal...
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Posted by admin on Dec 1, 2022 in |
Public health challenge due to respiratory tract infections has necessitated vehement research for promising substances against the causative agents. The leaves of Eucalyptus citriodora (E. citriodora, Myrtaceae) are used in Nigeria as tea, infusion or steam inhalation by patients as an alternative medicine to clear the airway and relieve symptoms; however, no scientific evidence exists to support or debunk this claim. This study aimed to evaluate the in-vitro antimicrobial effect of E. citriodora leaf essential oil and crude extracts against selected pathogens implicated in respiratory tract infections. The fresh leaves of E. citriodora were collected, identified and subjected to exhaustive fractionated extraction. The leaf essential oil was obtained by hydrodistillation using Clevenger-type apparatus and characterized using GC-MS. Aqueous extracts were obtained by hot infusion and decoction and characterized using HPLC-UV-DAD. The susceptibility of test pathogens Pseudomonas aeruginosa ATCC 27853, Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 25922, Salmonella paratyphi ATCC 9150 Candida albicans ATCC 10231, Klebsiella pneumonia and Streptococcus pneumonia to the extracts were evaluated by agar well diffusion...
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