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PREPARATION AND EVALUATION OF POLYHERBAL FORMULATION FOR ITS ANTIDIABETIC ACTIVITY AGAINST STREPTOZOTOCIN INDUCED DIABETES RAT MODEL
The present work was executed to evaluate the anti-diabetic potency of a polyherbal preparation. The objective of this study is to induce experimental diabetes mellitus using streptozotocin in normal Albino wistar rats and study the anti-diabetic activity of polyherbal formulation by comparison of changes in levels of glucose between normal and diabetic rats. The effect of methanol extract of poly...
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ANALGESIC ACTIVITY OF HYDROMETHANOLIC EXTRACT OF FICUS POLITA LEAVES
Ficus polita leaves have been used in traditional medicines to increase physical strength, work productivity and longevity, resistance to high altitude sickness, fatigue, depression, anemia, gastrointestinal ailments, infections, and nervous system disorders. The objective of this study was to evaluate the analgesic activity of hydromethanolic extract of F. polita leaves in rats using acetic acid-...
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TRADITIONAL PLANT MEDICINES AS A SOURCE OF NEW DRUGS IN CURRENT TRENDS
Before the advances in synthetic chemistry and discovery of antimicrobials in the 19th early to 21st centuries, plants provided the major source of medicines. Traditional knowledge is more and more an established resource for modern medical science. Ayurveda is the most ancient health care system and is practiced widely in India, Sri Lanka and other countries. This article reviews some of the past...
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MUSA PARADISIACA – A WONDER FRUIT
Over the past centuries phytochemical and phytopharmacological sciences established the compositions, biological activities and health-promoting benefits of numerous botanical products. Musa paradisiacal also known as Musa or banana in common terms are one of the world's most appealing fruits. Banana (Musa paradisiaca L., Musaceae) represents one of the most important fruit crops, with a global an...
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PHYTOCHEMISTRY AND PHARMACOLOGICAL IMPORTANCE OF POLYGONUM VISCOSUM: A REVIEW
Polygonum viscosum, belonging to the family Polygonaceae, is an annual herb which is highly distributed in Bangladesh, China, Nepal, Japan, and India. Like any other plant of the genus Polygonum, P. viscosum is significant from both phytochemical and pharmacological properties. Findings regarding the use of this plant in pain, fever, tumor, infection, inflammation, blood clots and so forth mark it...
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COMPARATIVE PHARMACOGNOSY AND PHYTOCHEMICAL ANALYSIS OF MEDICINAL PLANTS WITH ANTIDIABETIC ACTIVITY (PTEROCARPUS MARSUPIUM ROXB., AZADIRACHTA INDICA A. JUSS., TRICHOSANTHES DIOICA ROXB., SYZYGIUM CUMINI LINN. AND MOMORDICA CHARANTIA LINN.)
Diabetes mellitus is becoming a threat to the world’s population as it is spreading like an epidemic. Pterocarpus marsupium Roxb., Azadirachta indica A. Juss., Trichosanthes dioica Roxb., S. cumini Linn. and M. charantia Linn. are well known for their properties in the management of diabetes. In recent times, there has been significant growth in the field of Ayurvedic medicines because of their ...
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PHYTOCHEMICAL ANALYSIS AND EFFECTS OF AQUEOUS EXTRACT OF WITHANIA SOMNIFERA ON ISOLATED SMOOTH MUSCLE, PERFUSED HEART, BLOOD PRESSURE AND DIURESIS IN RATS
The plant Withania somnifera has many acclaimed medicinal uses. This work aims to explore the efficacy of the aqueous extract (AE) of W. somnifera on the isolated trachea and aorta rings, perfused heart, blood pressure and diuresis in rats. Phytochemical analysis of the whole plant of W. somnifera was carried out using standard extraction procedures followed by column chromatography. An aqueous ex...
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PHYTOCHEMISTRY AND PHARMACOLOGICAL PROPERTIES OF GYMNEMA SYLVESTRE (ASCLEPIADACEAE): A REVIEW
Gymnema sylvestre, is a traditional medicinal plant, belonging to the family of Asclepiadaceae; commonly distributed throughout the world, predominantly in tropical regions. The plant exhibits a broad range of therapeutic effects as an effective natural remedy for diabetes, dyspepsia, helminthiasis, constipation, hemorrhoids, jaundice, cardiopathy, asthma, bronchitis, leucoderma and several inflam...
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EVALUTION OF ANTHELMINTIC ACTIVITY OF RICINUS COMMUNIS LINN. LEAVES
Aqueous and ethanol-ethyl acetate chloroform-methanol extracts from the leaves of Ricinus communis were investigated for their anthelmintic activity against Pheretima posthuma, and three concentrations (50, 75 and 100 mg/ml) of each extract were studied for activity, in which paralysis and death time of the worm. Both the extract exhibited remarkable anthelminthic activity at all three concentrati...
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APPLICATIONS OF SURFACTANTS IN PHARMACEUTICAL FORMULATION DEVELOPMENT OF CONVENTIONAL AND ADVANCED DELIVERY SYSTEMS
The role of surfactants is very critical in the development of pharmaceutical formulations. The diverse applications in different delivery systems have been highlighted in different reports of formulation development for various conventional and advanced delivery systems. The relevancy of critical micelle concentration and HLB value for the section of surfactants for different drug delivery system...
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