Posted by admin on Jun 30, 2023 in |
Brugmanisa suaveolens, also known as the angel’s trumpet and a member of the Solanaceae family, is found throughout Asia, India, Europe, Australia, and North and South America. This study looks at current information on the distribution, phytochemistry, pharmacology, and toxicology of Brugmansia suaveolens (Solanaceae) utilizing the extracts or chemical compounds at this time, as found in various search engines. This plant has been used in traditional medicine throughout cultures as a muscle relaxant, nematicide, aphrodisiac, hallucinogen, and treatment for inflammation, rheumatism, asthma, and allergies. Hyoscyamine, a tropane alkaloid, is a key bioactive component of the plant with anticancer action. Additionally, hazardous consequences such as severe anticholinergic symptoms like delirium, hallucinations, and psychosis may be caused by this herb. Different chemical substances have been detected in the plant’s flowers, fruits, stems, and roots, including alkaloids, volatile chemicals (mostly terpenes), coumarins, flavonoids, steroids, and hydrocarbons. Atropine and scopolamine are primarily responsible for the plant’s toxicity. According to pharmacological research, an aqueous extract has an antinociceptive impact on mice. The ethanolic extract,...
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Posted by admin on Jun 30, 2023 in |
To develop a simple, specific, sensitive and robust bioanalytical method for determining Quinine in the human plasma with the help of LC-MS/MS API2000 various found parameters. Different Equipment experiment was found within the acceptance criteria, Different Column experiment was found within the acceptance criteria, and the Proposed Bioanalytical method for quantifying Quinine from K3EDTA based Human plasma was satisfactorily validated. It can be used to quantify Quinine from K3EDTA-based Human Plasma in Bioequivalence and Bioavailability...
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Posted by admin on Jun 30, 2023 in |
Alkaloids, flavonoids, steroids, and phenolic compounds are among the phytochemicals that have a significant impact on antimicrobial activity. These substances can be derived from several plant components, including the roots, stems, and leaves, and are used to treat bronchitis, cholera, dysentery, fever, and diarrhea. In this work, the phytochemicals from the dried leaves of Parthenium, Datura stramonium, and Calotropis gigantea are attempted to be extracted. These weeds are frequently found in India and are members of the Asteraceae, Solanaceae, and Apocynaceae families. The presence of phytochemicals, the effectiveness of the antibacterial effect on nine selected bacterial species, and the antifungal activity on eight fungi obtained from the Genohelix lab were all tested using aqueous, methanol, and n-hexane extracts. Aqueous and methanolic extracts from Datura stramonium and Calotropis gigantea revealed the presence of alkaloids and phenolic compounds, however, n-hexane extracts from all of the test plants failed to detect any phytochemical components. Compared to the conventional antibiotic penicillin, the antibacterial activity of Datura stramonium was most efficient against Staphylococcus citrus...
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Posted by admin on Jul 31, 2022 in |
Natural herbs have had to show profound action for many years. The phytochemicals present in plants responsible for preventing disease and promoting health have been studied extensively to establish their efficacy and understand their action’s underlying mechanism. Such studies have included identifying and isolating the chemical components and establishing their biological potency both by in-vitro and in-vivo studies in experimental animals and through epidemiological and clinical-case control studies in man. The present work describes “Isolation, Characterization and Biological Evaluation of Madhuca longifolia seeds”. The seeds were collected, authenticated, shade dried and powdered using a mechanical grinder. The powdered material was extracted by the Soxhletion method by using solvents in increasing order of polarity i.e, hexane, ethyl acetate and methanol. The percentage yield of hexane extract was found to be (57.8%), ethyl acetate extract (4.6%) and methanolic extract (18.9%) was respect to the powdered crude drug. Each extract was subjected to preliminary phytochemical screening using standard phytochemical methods. The hexane, ethyl acetate and methanol extracts were found to be rich...
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Posted by admin on Jul 31, 2021 in |
The present era aims to use medicinal plants and their constituents to treat various diseases. The synthetic drugs available in the market are associated with various side effects and follow a tedious and time-consuming process to synthesize. Natural drugs are safe and possess a large therapeutic window, thus gaining interest in the present scenario. These natural drugs are lacking in terms of their receptor action, so the present scenario aims to extract the active constituents of herbal drugs and study their profile aiming at a particular disease. In the present review, we presented the antiasthmatic potential of caffeine (extracted from tea leaves) by studying its effect on adenosine receptors. Our main aim is to study the active constituent present in a specific part of the plant to be extracted and used specifically for a specific receptor instead of the whole...
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