BIOANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF QUININE IN HUMAN PLASMA BY LC-MSAbstract
To develop a simple, specific, sensitive and robust bioanalytical method for determining Quinine in the human plasma with the help of LC-MS/MS API2000 various found parameters. Different Equipment experiment was found within the acceptance criteria, Different Column experiment was found within the acceptance criteria, and the Proposed Bioanalytical method for quantifying Quinine from K3EDTA based Human plasma was satisfactorily validated. It can be used to quantify Quinine from K3EDTA-based Human Plasma in Bioequivalence and Bioavailability Study.
Raman R. Chandak * and Vedant Mahajan
Department of Pharmacognosy, School of Pharmacy, GH Raisoni University, Saikheda, Madhya Pradesh, India.
18 July 2023
25 July 2023
26 July 2023
31 July 2023