Posted by admin on Feb 29, 2024 in |
Fast dissolving or mouth disintegrating tablets are oral delivery systems intended for a rapid breakdown of the dosage form in the mouth or oral cavity, in contrast to other conventional dose forms. Labetalol, an alpha-1-adrenergic antagonist of the third generation, has vasodilatory and antihypertensive properties. It is used to treat hypertension and angina. Using novel co-processed super disintegrants and physical combinations combining croscarmellose and crospovidone in 1:1, 1:2, 1:3, 2:1, and 3:1 ratios, this study attempts to produce and evaluate labetalol fast dissolving tablets. The direct compression method was used to make the tablets. The tablets work instantly since they dissolve quickly when used orally. Like liquid dosage forms, orally disintegrating tablets are easier to take and offer greater convenience. Important excipients called disintegrants are added to solid dosage forms in order to break or disintegrate tablets in aqueous media. The disintegrants enhance the formulation’s surface area, or tablet’s surface area, and counteract the cohesive forces that hold the particles...
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Posted by admin on Feb 29, 2024 in |
Paralysis is the temporary or permanent absence of voluntary muscle movement. Gadget problems can be crippling. Because changes in fear and muscles are affected. Partial, partial, or complete paralysis may occur in humans. Almost all causes of paralysis are spinal cord injury (SCI), head trauma, peripheral neuropathy, stroke, and multiple sclerosis. Bell’s palsy reasons transient facial paralysis. Not on the whole, muscle tissue themselves are the purpose, as this may also be because of a hassle around someplace alongside the chain of nerve cells that journey from the frame part in your brain and back once more. on this evaluate, gain an understanding greater about the forms of paralysis, their reasons, symptoms, complications, diagnosis and the maximum essential 37 medicinal plant for his or her software and therapy of illness associated with paralysis. Out of the 37 plant life documented, 11 flowers were pronounced for their capability to remedy paralysis. Even though, the facts on the recorded plants have been in particular discovered to be deficient, requiring right authentication...
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Posted by admin on Feb 29, 2024 in |
The biologically active compounds present in plants are called phytochemicals. Phytochemical analysis unlocks the secrets within these plants, revealing the identity of these valuable molecules. This review helps in study of exciting world of plant chemistry, utilizing diverse techniques to unveil the phytochemicals of various medicinal species. Analysing the profile of these phytochemicals in medicinal plants is crucial for understanding their potential therapeutic effects, identifying novel drug leads, and ensuring product quality control. The goal of phytochemical analysis is to evaluate the medicinal potential of plant by various methods like extraction, chromatographic techniques, spectroscopic methods for identifying and isolating their phytoconstituents. Extraction techniques are the main one. Digestion, maceration, and percolation are the examples of extraction techniques. Similarly phytochemical screening of Alkaloids, Flavonoids etc. also included in this study. Spectroscopic methods play a pivotal role in this process, offering a powerful tool to qualitatively identify and quantitatively analyse these fascinating molecules. Phytochemical study is very useful for us because of many applications are occurred especially in disease prevention or...
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Posted by admin on Feb 29, 2024 in |
There are numerous applications of the bamboo grass plant covered in this review paper. Bambusa arundinaceae (Retz.) Wild is an important species among the bamboo community. Young bamboo grass shoots can be processed into a variety of delectable, healthful meals and occasionally as medications. There are 26 species of bamboo in Bangladesh, classified into seven genus, encompassing both wild and domesticated exotics. The plant contains various bioactive compounds like silica 70 or Silicum as a hydrate of silicic acid, peroxide of iron, potash, lime, and alumina, proteins, phosphorus, iron, vitamin B, nicotinic acid, riboflavin, carotene, calcium phosphorus, thiamine, niacin, and oxalic acid. Diverse studies carried out on bans, by various researchers reported a wide spectrum of pharmacological actions like hepatoprotective, antioxidant, analgesic, antipyretic, anti-ulcer and antidiabetic activities,...
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Posted by admin on Feb 29, 2024 in |
Objectives: Silymarin is an anti-inflammatory agent that is used in the treatment of a variety of inflammatory disorders. The aim of the present study was to prepare and evaluate novel polymeric nanoparticles containing Silymarin. Materials and Methods: A 32 full factorial design was used to study the effect of Eudragit EPO and Pluronic F-68 on the characterization of nanoparticle suspensions. The polymeric nanoparticles were prepared by Nano precipitation technique. The prepared nanoparticles was evaluated by percentage yield, drug polymer compatibility using Fourier transform infrared (FTIR) spectroscopy and differential scanning calorimetric (DSC) analysis, drug content, entrapment efficiency, zeta potential, particle size, scanning electron microscopy, X-ray diffraction, in-vitro drug release studies, kinetic modelling, stability studies, and in-vivo animal studies. Results: The DSC study revealed that the drug was involved in complexation with nanoparticles. The average particle size of Silymarin nanoparticles was in the range of 114.4 nm to 136.7 nm. The zeta potential values were attained to ensure good stability of nanosuspensions. In-vitro release of the drug from nanoparticles follows the...
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