Posted by admin on Mar 31, 2022 in |
Many herbal remedies have been employed in various medical systems to treat and manage different diseases. Medicinal plants and their investigation of the phytoconstituents are much interested in today’s research. Herbal medicine uses medicinal plants for the prevention and treatment of diseases: it ranges from traditional and popular medicines in every country to the use of standardized and titrated herbal extracts. Generally, cultural rootedness enduring and widespread use in a Traditional Medical System may indicate safety, but not efficacy of treatments, especially in herbal medicine where tradition is almost completely based on remedies containing active principles at very low and ultra-low concentrations or relying on magical-energetic principles. Here, this study aims to evaluate the Pharmacognostic parameters and identify the Phytoconstituents. Hypericum oblongifolium (family: Guttiferae) is well known in India and is one of the most versatile medicinal plants having a wide spectrum of biological activity. It is a highly useful and traditionally used medicinal herbaceous plant found in tropical and subtropical areas of the world. The genus Hypericum consists...
Read More
Posted by admin on Mar 31, 2022 in |
Medicinal plants have been estimated as the richest holdings of traditional medicines and from these plants, many types of modern medicines were developed. Coscinium fenestratum (Gaertn.) Colebr. belongs to the family Menispermaceae and is considered a critically endangered medicinal plant. Traditionally it is used for antimicrobial agents, diabetes mellitus, cancer, and arthritis. In this study in-vitro pharmacological activities of leaf and stem extracts of C. fenestratum were evaluated. The solvent extracts were screened for antimicrobial activity against some clinically isolated bacterial and fungal cultures using the disc diffusion method. The antioxidant activity of extracts were tested by 2,2-diphenyl-1-picrylhydrazyl (DPPH) method. The acetone extract of stem showed potential antimicrobial activity than other extracts. All the pathogens were inhibited at very low concentration, very specific Klepsiella pneumoniae was inhibited at 0.156mg/mL and Phialophora verrucosa was inhibited at 0.078mg/mL of the stem extract. The methanol extracts of stem showed the highest antioxidant activity of 99.59%. followed by stem extracts of ethyl acetate (99.02%), acetone (98.79%), and petroleum ether(90.55%) were showed. Hence, the...
Read More
Posted by admin on Mar 31, 2021 in |
Aim: To investigate the hepatoprotective activity of Morus alba Linn. alcoholic leaves extracts against paracetamol-induced hepatitis in rats. Materials and Methods: The Morus alba leaves extracted with alcoholic (ALE), and water extract (AQE) against Paracetamol induced hepatotoxicity and using Standard drug is Liv-52. Preliminary phytochemical tests were done. Results: The ALE showed presence of alkaloids, flavonoids, carbohydrates, tannins, and steroids, did not produce any mortality. Paracetamol produced significant changes in biochemical parameters (increases in serum glutamate pyruvate transaminase (SGPT), Serum glutamate oxaloacetate transaminase (SGOT), alanine phosphatase (ALP) and serum bilirubin.), histological (damage to hepatocytes) using Standard drug Liv-52. Pre-treatment with ALE extract significantly prevented the biochemical and histological changes induced by Paracetamol in the liver. Conclusion: The present study shows that the ALE extract possessed hepatoprotective activity....
Read More
Posted by admin on Mar 31, 2021 in |
Stereospermum kunthianum Cham. is a small, to medium-sized tree, sometimes only a small shrub. Bark grey, smooth, sometimes flaking, revealing pale under bark. In Senegal this plant is used in traditional medicine against gastritis, asthenia, respiratory diseases but also as a wound healing. The present study was taken up to research an anti-bacterial activity in the trunk bark hydro-ethanolic extract and its fractions obtained by using different solvents. Extract and fractions were tested on clinical strains and reference strains of four bacteria: Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Enterococcus faecalis. The methods of diffusion in agar medium and micro-dilution in liquid medium were used. The results showed that on clinical strains, the lowest Minimum Inhibitory Concentration: MIC (0.156 mg/ml) was observed with the hydro-ethanolic extract and its aqueous fraction on Pseudomonas aeruginosa. With regard to the reference strains, the best activity was noted with the aqueous fraction with a MIC of 2.5 mg/ml on the Pseudomonas aeruginosa strain ATCC 27853. However, the standard antibiotics used are more effective...
Read More
Posted by admin on Mar 31, 2021 in |
Raw herbal samples used in the herbal medicine industry need to be properly identified for use in an herbal preparation. Plant parts of Woodfordia fruticosa (L.) Kurz belonging to the Lythraceae family, apart from some commercial uses, is known for its medicinal value in ethno medicines and various Indian traditional medicine systems, including Ayurveda. Flowers are reported high trade value (2000-5000 MT), are used in some Ayurvedic formulations such as Atisara, Raktapitta, Trsna, Vrana, Visarpa, Arjunarishta (Parthadyarishta), and Partharishtam. The present study aimed at botanical characterization and identification of raw leaf, flower, and stem bark herbal samples of Woodfordia fruticosa. Macroscopic and microscopic characters were studied using stereomicroscope and compound microscope. The morpho-anatomical description was provided for flower, leaf, and stem bark samples. Anatomical study of a leaf with a crescent-shaped vascular bundle, three different types of trichomes, and bark with linearly arranged rosette crystals crossing uniseriate medullary rays longitudinally were observed as characteristic features. Powder organoleptic and microscopic characters were described for each studied herbal sample. Characters compiled...
Read More