Posted by admin on Mar 31, 2026 in |
Silica (silicon dioxide) is a naturally abundant mineral found on earth. During the last decade, silica has received a lot of attention due to its newly proposed potential health benefits. To date, silica is an important bioactive dietary component that plays a critical role in its bioavailability and in maintaining human health in relation to skeletal and connective tissue health. Recent studies related to silica as a dietary component include bioavailability and analysis of silica within the body, nutrigenomics, biomedical technology, effects on bone health, potential cosmetic applications, and relationship with probiotics. In this review, silica will be defined, from where it came about, what it is composed of, and where it can be found. Special attention will be focused on silica-rich sands that are found throughout the world. Dietary silica and naturally occurring silica in plant-based foods, beverages, and functional products will be discussed. Topics including absorption, metabolism, biological roles of silica within the human body, and interactions with calcium and trace minerals will be reviewed. Special attention...
Read More
Posted by admin on Mar 31, 2026 in |
In ancient systems like Unani, Tibb, Ayurveda, and Siddha, Nigella sativa is a frequently utilized medicinal herb. Its oil and seeds have long been used in food and healing. N. sativa is suggested in Tibb-e-Nabwi (Prophetic Medicine) and is considered a key medicinal cure in Islamic literature. In addition to being used as analgesics, diuretics, and hunger stimulants, the seeds have been used to treat hypertension, liver ailments, digestive difficulties, diarrhea, and skin concerns. Numerous pharmacological actions, such as anticancer, antidiabetic, immunomodulatory, renal-protective, anti-inflammatory, antimicrobial, bronchodilator, spasmolytic, hepato-protective, gastro-protective, and antioxidant properties, are shown by scientific research. The main bioactive substance, thymoquinone, is responsible for the majority of therapeutic advantages. This review aims to provide a comprehensive survey of the pharmacognosy, chemical composition, and pharmacological properties of N. sativa...
Read More
Posted by admin on Mar 31, 2026 in |
The development of anthelmintic resistance and the higher expense of traditional anthelmintic medications caused the Zingiber stigation of medicinal plants as a potential substitute of anthelmintics, utilizing the P. posthuma adult earthworm. The present investigation focuses on the anthelmintic potential of three traditionally used plants of Bangladesh: Zingiber officinale (family: Zingiberaceae), Momordica charantia (family: Cucurbitaceae), and Moringa oleifera (family: Moringaceae) at all tested concentrations (25 mg/ml, 50 mg/ml, and 100 mg/ml), the extracts showed anthelmintic activity. The greatest effect was seen at 100 mg/ml. At higher concentrations, Momordica charantia (Korola) showed the strongest anthelmintic effect among the plants, followed by Zingiber officinale (Ada) and Moringa oleifera (Sajna pata). The traditional use of these plants as natural anthelmintic agents is supported by these...
Read More
Posted by admin on Mar 31, 2026 in |
In recent decades, oral health management has witnessed a paradigm shift by integrating bioactive materials into dental therapeutics. Among these, bioactive glasses (BGs) that were originally developed by Larry Hench in 1969 have garnered significant attention because of their distinctive capacity to bond with bones and soft tissues of the body, while stimulating biological responses that promote healing and regeneration. Bioglass was the first synthetic material that formed a chemical bond with bone. The principal mechanism underlying the bioactivity of BGs lies in their surface reactions in aqueous environments, where they release therapeutic ions like Ca²⁺, Na⁺, PO₄³⁻, and Si⁴⁺, that lead to the formation of a hydroxycarbonate apatite (HCA) layer that mimics natural bone mineral. Furthermore, functionalization of bioactive glasses (BGs) with therapeutic metal ions like Ag⁺, Zn²⁺, Cu²⁺, Sr²⁺ and herbal bioactives has emerged as a promising strategy to enhance their antimicrobial, osteogenic, angiogenic, and anti-inflammatory properties, thereby broadening their applications in dental and ocular implantology, orthopedics, and wound healing. Despite the widespread recognition of its benefits,...
Read More
Posted by admin on Mar 31, 2026 in |
The search for safer alternatives to synthetic neuroactive drugs has increased interest in medicinal spices with potential central nervous system (CNS) activity. Trachyspermum roxburghianum, a traditionally used aromatic spice, remains poorly explored for its neuropharmacological effects. This study evaluated the CNS depressant activity of the methanolic extract of T. roxburghianum seeds in mice. CNS depressant activity was assessed using forced swimming test (FST), tail suspension test (TST), and thiopental sodium-induced sleeping time assay in Swiss albino mice. The extract was administered orally at doses of 50, 100, and 200 mg/kg, while diazepam (1 mg/kg, i.p.) served as the reference standard. Acute oral toxicity was evaluated up to 2000 mg/kg. Qualitative phytochemical screening was performed, and statistical analysis was conducted using paired Student’s t-test (one-tailed). The extract produced a dose-dependent increase in immobility time in both FST and TST. In the thiopental-induced sleeping time test, the extract significantly reduced sleep onset latency and prolonged sleep duration at higher doses. Phytochemical analysis confirmed the presence of flavonoids, terpenoids, saponins, phenolics, tannins,...
Read More
