Posted by admin on Mar 31, 2021 in |
Aim: To investigate the hepatoprotective activity of Morus alba Linn. alcoholic leaves extracts against paracetamol-induced hepatitis in rats. Materials and Methods: The Morus alba leaves extracted with alcoholic (ALE), and water extract (AQE) against Paracetamol induced hepatotoxicity and using Standard drug is Liv-52. Preliminary phytochemical tests were done. Results: The ALE showed presence of alkaloids, flavonoids, carbohydrates, tannins, and steroids, did not produce any mortality. Paracetamol produced significant changes in biochemical parameters (increases in serum glutamate pyruvate transaminase (SGPT), Serum glutamate oxaloacetate transaminase (SGOT), alanine phosphatase (ALP) and serum bilirubin.), histological (damage to hepatocytes) using Standard drug Liv-52. Pre-treatment with ALE extract significantly prevented the biochemical and histological changes induced by Paracetamol in the liver. Conclusion: The present study shows that the ALE extract possessed hepatoprotective activity....
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Posted by admin on Mar 31, 2021 in |
Stereospermum kunthianum Cham. is a small, to medium-sized tree, sometimes only a small shrub. Bark grey, smooth, sometimes flaking, revealing pale under bark. In Senegal this plant is used in traditional medicine against gastritis, asthenia, respiratory diseases but also as a wound healing. The present study was taken up to research an anti-bacterial activity in the trunk bark hydro-ethanolic extract and its fractions obtained by using different solvents. Extract and fractions were tested on clinical strains and reference strains of four bacteria: Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Enterococcus faecalis. The methods of diffusion in agar medium and micro-dilution in liquid medium were used. The results showed that on clinical strains, the lowest Minimum Inhibitory Concentration: MIC (0.156 mg/ml) was observed with the hydro-ethanolic extract and its aqueous fraction on Pseudomonas aeruginosa. With regard to the reference strains, the best activity was noted with the aqueous fraction with a MIC of 2.5 mg/ml on the Pseudomonas aeruginosa strain ATCC 27853. However, the standard antibiotics used are more effective...
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Posted by admin on Mar 31, 2021 in |
Raw herbal samples used in the herbal medicine industry need to be properly identified for use in an herbal preparation. Plant parts of Woodfordia fruticosa (L.) Kurz belonging to the Lythraceae family, apart from some commercial uses, is known for its medicinal value in ethno medicines and various Indian traditional medicine systems, including Ayurveda. Flowers are reported high trade value (2000-5000 MT), are used in some Ayurvedic formulations such as Atisara, Raktapitta, Trsna, Vrana, Visarpa, Arjunarishta (Parthadyarishta), and Partharishtam. The present study aimed at botanical characterization and identification of raw leaf, flower, and stem bark herbal samples of Woodfordia fruticosa. Macroscopic and microscopic characters were studied using stereomicroscope and compound microscope. The morpho-anatomical description was provided for flower, leaf, and stem bark samples. Anatomical study of a leaf with a crescent-shaped vascular bundle, three different types of trichomes, and bark with linearly arranged rosette crystals crossing uniseriate medullary rays longitudinally were observed as characteristic features. Powder organoleptic and microscopic characters were described for each studied herbal sample. Characters compiled...
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Posted by admin on Mar 31, 2021 in |
Herbal medicines have attracted the researcher’s attention nowadays as scientific evidence is coming regularlyon their safety and efficacy. Katan (Linum usitatissimum Linn) is a potent therapeutic agent of Unani medicine for respiratory tract diseases since ancient times. Unani scholars have described Katan as having pharmacological effects, i.e., Mohallil-e-Auram Munaffis-e-Balgham Mulattif Munzij, with its therapeutic uses in various respiratory tract diseases, i.e., Nazla, Zukam, Sual Baghami, Warme Urooqe Khashina, Zeequnafs, and Dama. This literary research is an attempt to highlight the various researches carried out on Katan in many respiratory tract diseases so it can provide guidance to researchers in the coming days. From these studies it has been proved that Katan (Linum usitatissimum) is anti-inflammatory agent. Moreover, it also has an antibacterial, antiallergic effect and has a significant effect on COPD, asthma of childhood and adults. These findings prove the claims of the Unani medical scholars made centuries ago about the therapeutic effects of Katan in various respiratory tract diseases. Based on centuries-old experience of Unani scholars, we can...
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Posted by admin on Mar 31, 2021 in |
Cancer is a non-communicable life-threatening disease and a majority of cancers are caused due to inflammatory responses and association with precursor lesions termed as proliferative inflammatory factors. Inflammatory response arises because of dysfunction of anti-oxidative proteins due to DNA damage and may increase oxidative stress. This review mainly focuses on the inflammatory factors which trigger specific pathways inside the cell and create a tumour microenvironment that subsequently leads to cancer induction and progression. We are providing information about the role of various plant derived active compound and their role in treatment of cancer via induction of chronic inflammation and altering the level of reactive oxygen species (ROS). In this review, we will also document currently available treatments and their possible therapeutic implications in ameliorating the ailments that arise due to cancer. In the later section of this review, we have added notes on the challenges that need to be addressed to improve the efficiency of drugs derived from medicinal plants. It appears that herbal therapies are effective for targeting the...
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