Posted by admin on Aug 31, 2025 in |
The present study focuses on identification of bioactive compounds from Methanolic extraction of Indigofera prostrate, by GC–MS analysis and also evaluated the efficacy of Indigofera prostrate for antioxidant activity. Phytochemical screening of the Methanolic extraction of Indigofera prostrate revealed the presence of flavonoids, phenolic compounds, triterpenoids, tannins, saponins, amino acids, proteins, Steroids, Gums and carbohydrates. Gas chromatography-mass spectrometry (GC-MS) analysis of the methanol extract of Indigofera prostrate was performed on a GC-MS equipment. The GC-MS analysis has shown the presence of different bio active compounds in the Methanolic extract of Indigofera prostrate. A total of 14 compounds were identified in methanolic extraction in that the main active compounds are Campesterol, Stigmasterol, γ-Sitosterol, Lupeol. From the results, it is evident that Indigofera prostrate contains various phytocomponents and is recommended as a plant of phytopharmaceutical...
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Posted by admin on Jun 30, 2025 in |
Chocolate is the most loving food among the people. It is the easiest form to chew and absorb for every individual. This research deals into the Innovative application of herbal chocolates, a delightful fusion of traditional enjoyment and holistic well-being. The blending of herbal ingredients with the luxurious texture of chocolate has given rise to a new category of confectionery that not only satisfies sweet cravings but also offers potential health advantages. The essential target of this study was to formulate and evaluate nutritious chocolate and nutritional supplement containing anti arthritis property. Chocolate is a range of products derived from cocoa (cocoa) mixed with fat and finely powered coconut sugar to produce a solid confectionery. Sesame is the herbal drug which has several medicinal properties, like anti arthritis property, antioxidant property, from the prevention of rheumatoid arthritis. Sesame was used to improve blood pressure and act as anti aging agent. Thus, we have to formulate the chocolate with aqueous extract of sesame. Chocolate is a sophisticated and infinitely adaptable...
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Posted by admin on Jun 30, 2025 in |
This work aims to contribute to the phyto-therapeutic treatment of oral diseases that do not have a recognized management program, such as malaria, HIV-AIDS and tuberculosis. The aim is to qualitatively and quantitatively determine the chemical composition of Anacardium occidentale and Cocos nucifera, as well as the toxicity and sensitivity to their extracts of the microbial strains responsible for oral infections. Medicinal plant sellers in 03 markets of Porto-Novo use plant species to treat oral infections. C. nucifera (A) and A. occidentale (B) were the most frequently cited, used in decoction form. Qualitative phytochemical analysis using the standard method showed that C. nucifera roots contain tannins, steroids, mucilages, leuco-anthocyanins and alkaloids, while A. occidentale roots contain tannins, flavonoids, anthocyanins, leuco- anthocyanins, steroids, reducing compounds, coumarins and mucilages. The contents of total phenols (18.79±0.46 mgEAG/g(A)) and (20.05±1.01 mgEAG/g (B)), flavonoids (39.04±18.8 mgEQ/g) for extract B, condensed tannins (8.36±0.22 mgEC/g (A)) and (5.77±0.27mgEC/g(B)), justify the biological potential of these plants. Evaluation of the free radical scavenging activity of the decocts of...
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Posted by admin on Jun 30, 2025 in |
Objective: Knowledge about medicinal plants can contribute to modern therapeutics. Impatience walleriana [Family: Balsaminaceae] an ornamental, nutritive herb has relevance in African and Asian traditional medicines. Traditionally I. walleriana is used for anti-inflammatory, anti-dermatitis effects and is known to relieve skin irritation. It is applied on skin to treat bacterial and fungal infection. Acne is a common skin disorder mainly seen in adolescents. Treatment for acne revolves around anti-bacterial, anti-inflammatory and antioxidant effects of drugs. Anti-bacterial and antioxidant activities of I. walleriana have been reported previously reported. In the present study anti-acne potential of I. walleriana extract is evaluated against Propionibacterium acne and an attempt has been made to co-relate findings with traditional claims. Methods: Hydroalcoholic extract of aerial parts of I. walleriana is evaluated for effectiveness against P. acne by measuring zone of inhibition using well diffusion method and by finding MIC. Tetracycline is used as standard. Results: Results of Zone of Inhibition are promising with an average of 11mm, 08mm and 4mm in the duplicate readings obtained....
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Posted by admin on Jun 30, 2025 in |
Sickle cell disease (SCD) treatment and management remain a challenging puzzle, especially among developing Nations. We evaluated catechin’s sickling-suppressive properties using in-vitro and bioinformatics approaches in human sickle erythrocytes. Sickling was maximally induced (76%) using 2% sodium metabisulfite (SMS) at 3h. Addition of catechin prevented the sickling by SMS at 1mM (81.19%) and reversed the same at 1mM (84.63%), with IC50 values of 1.026µM and 1.103µM, respectively. Based on functional chemistry, catechin alters the functional groups of certain notable compounds within erythrocytes, favouring its anti-sickling effects, as indicated by the observed bends and shifts. From GC-MS and LC-MS analyses, it was observed that catechin treatment favours fatty acid alkyl monoesters (FAMEs) production with concomitant shutting down effects on selenocompound metabolism. Pathway enrichment and topology analyses revealed activation of fatty acid biosynthesis, linoleic acid metabolism and steroid hormone biosynthesis pathways upon catechin treatment. Thus, sickling-suppressive effects of catechin could potentially be associated with modulation of oxygenated and deoxygenated haemoglobin via alteration of human sickle erythrocytes’ functional chemistry and metabolic pathways...
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