Posted by admin on Jun 30, 2022 in |
Carissa carandas Linn. is an evergreen plant of the Apocynaceae family. It is native to India and also found in Bangladesh, Sri Lanka, Indonesia, Malaysia, Pakistan, and Myanmar. Almost every part of these plants has been investigated for various pharmacological activities. Among all parts, leaves are less investigated. The present study explores the hepatoprotective activity of 60 % ethanolic extract of leaves of Carissa carandas Linn. Extraction of fresh mature leaves by the process of maceration using Petroleum ether gave 0.84 gm crude extract and a yield of 1.68 %. Extraction by using 60 % Ethanol gave 6.9 gm and a yield of 13.8 %. This crude extract was investigated for the evaluation of a hepatoprotective activity. The carbon tetrachloride (CCl4) induced method was used to study hepatoprotective activity. The extract showed significant dose-dependent hepatoprotective activity when compared with negative control group as the release of enzymes and bilirubin decreased with increasing dose of...
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Posted by admin on Jun 30, 2022 in |
The study focuses on the green synthesis of silver sulfide nanoparticles using aqueous Senna occidentalis (L.) extract as reducing, capping, and stabilizing agents. Fourier Transform Infra-red Spectroscopy (FTIR) and Scanning electron microscopy (SEM) characterized the synthesized silver sulfide nanoparticles. FT-IR spectrum of Senna occidentalis leaves aqueous extract as shown in Fig. 3 below shows a number of peaks, thus reflecting its complex nature. The bands at 3175cm-1 is characteristic of the alcohol/phenol –OH stretching vibration, 2361.44cm-1 an attribute O=C= Stretching representing carbon dioxide. The weak peak at 1594cm-1 is assigned for C=O bending, indicating carboxylic acid, and the band at 995cm-1 represents the C=C bending signifying alkene. Fig. 4 below shows the FTIR result of the synthesized silver sulfide nanoparticle at different bands. The bands at 3785 and 3703 cm-1 correspond to O-H stretching vibration, indicating the presence of alcohol/phenol; the peak at 3406 cm-1 reflects N-H stretching of alphatic primary amine. Bands at 2919 and 2855.82cm-1 correspond to the C-H stretching of aromatic compounds. The band at 1713.88cm-1...
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Posted by admin on May 31, 2022 in |
Vetiveria zizanioides (L.) Nash has been suggested in the Indian system of medicine as the roots of Usira for a number of diseases such as fever, dysuria, fatigue syndrome, wound healing, skin disorders, etc. (Jvara, Trishna, Mutrakrachhra, Vrana). This will be created helpfulness towards this medicinal plant and for preparation of different Ayurvedic formulations i.e Usira sava, Yogarajaguggulu, Sadanga Kvatha Curna. The objective of the present study is to develop the pharmacognostic and phytochemical profiles of Vetiveria zizanioides (L.) Nash root. The present study considers the detail investigation of macroscopy, microscopy, preliminary qualitative phytochemical analysis, physicochemical evaluations and HPTLC chromatography profiling. Microscopical investigation shows the presence of rectangular cells of epidermis, elongated and polygonal parenchyma groups, oval aerenchymatous cells, cork cells, elongated cells sclereids, sclerenchymatous stone cells, groups of sclerenchymatous fiber, prismatic crystals of calcium oxalate and starch grains. The presence of various secondary metabolites was confirmed by phytochemical screening and HPTLC profiling. Identification and authentication of roots may be helpful from botanical and chemical screening data for developing...
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Posted by admin on May 31, 2022 in |
Using the plant as a source of medicine is one of the major campaigns in the field of alternative therapy. This study was conducted to investigate the antimicrobial activity of Leptadenia hastate root. The root of this plant was collected, dried, and ground. The powder was subjected to extraction by cold maceration using water and methanol. The in-vitro antimicrobial activity of the extract was tested against four strains of bacteria: Staphylococcus aureus, Pseudomonas aeruginosa, E. coli, Bacillus cereus and one fungus Candida albicans using the agar diffusion method. DMSO was used as a negative control; Ciprofloxacin was used as a positive control for bacteria and fluconazole as a positive control for fungi. The agar dilution method determined the minimum inhibitory concentration (MIC) of crude extract. The phytochemical analysis was conducted to determine the secondary metabolites. The antimicrobial activities show that methanol extract of Leptadenia hastate was only sensitive against Bacillus cereus and Candida albicans out of five organisms tested, while aqueous extract does not show activity against any organism...
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Posted by admin on Apr 30, 2022 in |
Inflammation is initiated as a healing process by the tissue in response to an injury by pathogens, irritants or cell damage. Piper attenuatum B. Ham is a rare piper species found in the tropical, sub-tropical region and mainly found in the southern part of India. A plant has constituents like alkaloids, amides, glycosides, tannins etc., which are responsible for its therapeutic efficacy. This research focuses on the use of leaves of Piper attenuatum B. Ham as anti-inflammatory agents. The phytochemical and analytical evaluation was done for ethanolic leaf extract. Various part of the plant is used for treating fever, malaria, diuretic, and cancer. Piperine is a major alkaloid found in almost all piper species & responsible for anti-inflammatory activity. In the present study, ethanolic leaf extract of Piper attenuatum B. Ham at doses 200mg/kg and 400mg/kg showed significant in-vivo anti-inflammatory activity in carrageenan-induced paw edema in rats and in-vitro anti-inflammatory activity by protein denaturation method for dose 500, 400, 300, 200 & 100...
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