Posted by admin on Jan 30, 2026 in |
Indonesia is one of the largest agricultural countries in the world. In 2022, approximately 88.89% of the workforce was employed in the agricultural sector. One of the most important agricultural practices is the use of pesticides, which are essential for pest control. Organophosphates are widely used pesticides, and chlorpyrifos is one of the most commonly applied organophosphate insecticides. However, chlorpyrifos exposure may cause adverse health effects, including poisoning, organ damage, mortality, and insulin resistance. Butyrylcholinesterase (BChE) activity and serum glucose levels are important biomarkers for evaluating chlorpyrifos toxicity, as exposure to chlorpyrifos can decrease BChE activity and increase serum glucose levels. Chlorpyrifos is available in two forms, analytical standard chlorpyrifos (Pestanal) and trademark formulations such as Dursban 200 EC. However, studies comparing the effects of trademark and analytical standard chlorpyrifos on BChE and serum glucose levels are still limited. This study aimed to compare BChE activity and serum glucose levels between control and treatment groups, as well as between Pestanal and Dursban treatments. Rats were orally administered Pestanal or...
Read More
Posted by admin on Jan 30, 2026 in |
The genus Impatiens encompasses a diverse array of species valuable as sourcs of natural medicine some of which remain unexplored and insufficiently characterized. Impatiuens is a reservoir of metabolites such as phenolics, phytosterols, triterpenoids, and peptides which exhibit spectrum of activities including antimicrobial, cytotoxic, anti-inflammatory, antioxidant and anti-anaphylactic. Impatiens walleriana belonging to the family balsaminaceae is known for its aesthetic appeal and as folk medicine. Drug resistant strains of Candida and Aspergillus have made fungal infection treatment difficult and plants are serving as good alternatives. Impatiens walleriana is anti-microbial and traditionally applied to skin in folk medicine but has not been specifically screened for its anti-Candida albicans effectiveness hence, the present in-vitro study. The hydroalcoholic extract of the aeria parts of Impatiens walleriana has shown anti-Candida albicans effect with MIC 3.3mg/ml and ZOI ranging from 9mm to 20mm with maximum effectiveness at 100mg concentration in the triplicate readings taken for the selected doses 50mg, 100mg and...
Read More
Posted by admin on Nov 30, 2025 in |
Latex-bearing plants represent a rich source of bioactive compounds with significant medicinal value with wound healing property, antimicrobial activity, antiinflammatory and anticancer activity. The present investigation was aimed at evaluating the antioxidant activity, protease characterization and antimicrobial activity of latex extracts of Plumeria alba, Euphorbia grantii and Calotropis gigantea. Phytochemical analysis revealed that Calotropis gigantea latex contained the highest phenolic content, while Plumeria alba showed maximum protein and carbohydrate content. Antioxidant assays such as DPPH radical scavenging, reducing power assay and lipid peroxidation inhibition demonstrated strong antioxidant activity, particularly in Calotropis gigantea latex. Antimicrobial screening against Staphylococcus aureus using agar well diffusion method showed the highest zone of inhibition for Calotropis gigantea. Protease activity was maximum for Euphorbia grantii with optimal pH 8, with temperature optima of 40°C for Plumeria alba and Euphorbia grantii and 60°C for Calotropis gigantea. These findings support the traditional medicinal use of plant latex and suggest its potential application in pharmaceutical and industrial...
Read More
Posted by admin on Nov 30, 2025 in |
Mollugo pentaphylla L. (Molluginaceae), commonly known as carpetweed, has tremendous medicinal importance. Although the plant has been scientifically evaluated for its various biological activities but no work has not been carried out till date on comparative pharmacognostic characterization of the in-vivo plant and leaf callus. This study aims to investigate the comparative pharmacognostic and physicochemical standards for aerial parts and leaf callus of M. pentaphylla. The measures taken were macroscopic, organoleptic study, anatomy, powder microscopy, ash values, loss on drying, fluorescence analysis and extractive yield. This is the first study providing complete pharmacognostic profile of M. pentaphylla and hence will be useful for identification and authentication of the species for future...
Read More
Posted by admin on Nov 30, 2025 in |
Medicinal plants play a vital role in addressing health problems, particularly in Africa, where they often constitute the primary therapeutic resource. Encouraged by the WHO, which recommends their integration into health systems, their use nevertheless requires rigorous control based on identification. In Côte d’Ivoire, among the most widely used botanical families are the Fabaceae, renowned for the diversity of their species with pharmacological properties. This study presents, a micrographic and chemical analysis of three plants from this family: Abrus precatorius, Bafia nitida, and Desmodium adscendens. The analyses performed included micrographic examination of leaf powders, phytochemical screening of hydroethanolic extracts, using thin-layer chromatography, and chemical analysis by HPLC-ESI(+)-Q/TOF. Microscopic analysis allowed us to identify the characteristic elements. Chemical analysis revealed the presence of several groups of secondary metabolites (alkaloids, flavonoids, quinones, tannins, sterols, terpenes, and polyphenols), confirming the potential of these plants as sources of bioactive molecules and highlighting the importance of their valorization and integration into healthcare...
Read More
