Posted by admin on Oct 31, 2023 in |
This review highlights trends in traditional medicine and medicinal plant research and has the purpose of inspiring research focusing on accelerating the integration of traditional medicines into mainstream healthcare systems. Comprehensive literature resources accessible via Google’s search engine were systematically reviewed and described. Traditional medicines in general and traditional African medicine in particular are described. The historical contribution of medicinal plant research to the start of the entire enterprise of drug discovery and development as well as the pharmaceutical industry is highlighted. The decline of traditional medicine during the 19th and 20th centuries and the revival of interest in it towards the end of the 20th century are briefed. The role of conventional new chemical entity-based drug discovery strategies and associated successes and drawbacks related to medicinal plant research plus subsequent advocates foran alternative approach based on traditional medicine inspired by reverse pharmacology by the medicinal plant research community is emphasized. Overall, this review discussed, in addition to applying the well-established and science- and technology-supported drug discovery approach, adopting...
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Posted by admin on Oct 31, 2023 in |
The process of new drugs development is enforced by the success of herbal drugs in pharmaceutical market. Another approach to natural product drug discovery is to utilize the information derived. From industrial view point regarding sufficient supply of natural product derived active constituents. Musa acuminata has been used of the management of wound healing, fever, cough, bronchitis, sexually transmitted infection, allergic infection, dysentery, and non communicable diseases. This study was designed to assess its phytochemical and wound healing property on the male Wister rats. The roots of Musa acuminata is extract in Soxhlet extraction in three deferent methods (i) Chloroform extract (ii) Petroleum ether extract (iii) Ethanol extract. And for pharmacological activity five group ware created each group contain four animals which weight between 150-180gm. Group-1 is treated on normal control, Group-2 is treated on topically with hydrophilic ointment base, Group-3 is treated topically with framycetin sulphate cream 1% w/w, Brand name is soframycin, Group-4 is treated on ethanol extract, Group-5 is treat on chloroform extract and study the...
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Posted by admin on Aug 31, 2023 in |
Pergularia is an annual herbaceous plant in the family of Pergularia daemia linn native to India and Shrilanka. Pergularia daemia linn has shown anti-bacterial property which makes it an essential herb in the treatment of various infections. This study was to check the effectiveness of Pergularia daemia lin against the microbial species Staphylococcus aurens, to observe the zone of inhibition and to develop a topical gel formulation of Pergularia daemia linn for the treatment of acne. The extraction was done by maceration method and continues with phytochemical screening and herbal gel formulation using hydroxypropyl methyl cellulose as a base with different concentration 2%v/v, 4%v/v, 6%v/v and 8%v/v. The gel was evaluated for the physical appearance, ph, homogeneity and antibacterial activity. Different concentration of Pergularia daemia linn methanolic extract exhibited relatively good antibacterial activity. It was concluded that the gel formulation having higher concentration (8%) is found to be good consistency compared to 2%, 4% and 6%v/v and can be used to treat the antibacterial...
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Posted by admin on Aug 31, 2023 in |
Nanotechnology is a rapidly growing area of scientific interest due to its wide applications in catalysis, solar energy, waste management, and sensing technology. Nanomaterials are efficiently used in the field of medicine for the purpose of drug delivery, diagnosis, treatment of cardiovascular diseases, wound healing, and development of antimicrobial agents. The present study aimed to evaluate the effect of Costus afer-AgNPs extract on the PCV level of male rats. In this experimental study, 18 adult male rats were used. The rats were randomly divided into six groups. The first group (control) adequately consumed compressed food and water without any restrictions during the experiment. The second, third, fourth, fifth, and sixth experimental groups respectively consumed 200mg, 400mg, 600mg, 800mg, and 1000mg Costus afer-AgNPs extract per kilogram body weight in a daily manner. Blood samples were taken from all groups after four weeks through anesthesia. PCV and Hb test was carried out using the blood serum. The collected data were analyzed using SPSS, ANOVA, and LSD tests. PCV levels significantly increased...
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Posted by admin on Aug 31, 2023 in |
Background: Caesalpinia bonduc (L.) Roxb. belonging to family Caesalpiniaceae, commonly known as ‘Kuberaksha’, is a large scandant shrub. The stem bark is useful as febrifuge, emmenagogue, anthelmintic, germicidal and anti-pyretic. Aim: The present study was conceived to standardize the stem bark of Caesalpinia bonduc to determine correct identity and purity of the drug have been undertaken besides in detection of adulteration. Materials and Methods: Pharmacognostical studies include (study of morphological characters), microscopical characters and powder microscopy and physicochemical parameters along with phytochemical, histochemical studies and fluorescence behavior were studied. Results: Transverse section of stem bark revealed the presence of outer most cork interspersed with stone cells, inner phelloderm cells with rhombic crystals and biseriate medullary rays. Tangential Longitudinal Section (T.L.S) revealed presence of uni to biseriate medullary rays, mostly biserate. Physicochemical standards showed that foreign organic matter (Nil), loss on drying (11.07%), total ash (5.45%), acid insoluble ash (0.45%), water soluble ash (1.45%), petroleum ether extractive (0.45%), chloroform (1.65%), ethanol (6.5% ), methanol (7.55%), water (11.65%). Preliminary phytochemical screening...
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