PHARMACOGNOSTICAL STUDIES ON THE STEM BARK OF CAESALPINIA BONDUC (L.) ROXB.
AbstractBackground: Caesalpinia bonduc (L.) Roxb. belonging to family Caesalpiniaceae, commonly known as ‘Kuberaksha’, is a large scandant shrub. The stem bark is useful as febrifuge, emmenagogue, anthelmintic, germicidal and anti-pyretic. Aim: The present study was conceived to standardize the stem bark of Caesalpinia bonduc to determine correct identity and purity of the drug have been undertaken besides in detection of adulteration. Materials and Methods: Pharmacognostical studies include (study of morphological characters), microscopical characters and powder microscopy and physicochemical parameters along with phytochemical, histochemical studies and fluorescence behavior were studied. Results: Transverse section of stem bark revealed the presence of outer most cork interspersed with stone cells, inner phelloderm cells with rhombic crystals and biseriate medullary rays. Tangential Longitudinal Section (T.L.S) revealed presence of uni to biseriate medullary rays, mostly biserate. Physicochemical standards showed that foreign organic matter (Nil), loss on drying (11.07%), total ash (5.45%), acid insoluble ash (0.45%), water soluble ash (1.45%), petroleum ether extractive (0.45%), chloroform (1.65%), ethanol (6.5% ), methanol (7.55%), water (11.65%). Preliminary phytochemical screening of various extracts showed the presence of alkaloids, phenolic compounds and tannins, phytosterols, flavonoids, terpenoids and carbohydrates (were found be major components), besides histo-chemical studies and fluorescence behavior is given. Conclusion: Established Pharmacognostical characters, physic-chemical and phytochemical parameters of Caesalpinia bonduc stem bark will serve as standards of drug in the crude form and also would help in distinguish the drug from its adulterants or other closely related species. The study will provide referential information for correct identification of the crude drug.
Article Information
2
502-508
1640 KB
78
English
IJP
J. Shashikanth
Center of Medicinal Plants Research in Homoeopathy (CMPRH), Central Council for Research in Homeopathy (CCRH), Ministry of AYUSH, Government of India, 3/126, Indira Nagar, Emerad, The Nilgiris, Tamil Nadu, India.
jaleshashikanth2000@gmail.com
13 September 2023
24 September 2023
29 September 2023
10.13040/IJPSR.0975-8232.IJP.10(9).502-08
30 September 2023