The optimization of aqueous and non-aqueous solubility of a drug or a drug-like molecule can be examined via the Aspen Plus simulation platform. Paracetamol (solute) will be taken as a case study. The following solvents were used in our dry (virtual) lab experiment: water, paracetamol (PARACTML), used as a solid solute, Di-Ethylene-Glycol (DEG), 1,2-Propanediol (PROPGLYC), and Poly-Ethylene-Glycol...
FOLK MEDICINAL PLANTS USED BY THE SANTAL TRIBAL PRACTITIONERS AGAINST DIARRHEA AND DYSENTERY IN TANORE UPAZILA OF RAJSHAHI DISTRICT, BANGLADESH
This paper presented the traditional uses of 20 plant species belonging to 14 families that are used by the Santal tribal practitioners in Tanore Upazila of Rajshahi district, Bangladesh for the treatment of diarrhoea and dysentery diseases. During the study, interviews were conducted with the help of a semi-structured questionnaire and the guided field walks method. The medicinal plants tradition...
Since, ancient time, plants have been an exemplary source of medicine. Ayurveda and other Indian literature mention the use of plants in the treatment of various human ailments. Ficus benghalensis Linn is a large evergreen tree found throughout forest tracts of India. It is a popular indigenous system of medicine like Ayurveda, Siddha, Unani and Homeopathy. In the traditional system of medicine, v...
Kidney is a vital organ of the human body which performs the very important function of formation of urine. Unani system of medicine has illustrated its anatomy, physiology and diseases occurred due to its different abnormalities. Kidney has the four common powers viz; Quwwate Jazibah (absorptive power), Quwwate Hazimah (digestive power), Quwwate Masikah (retentive power) and Quwwate Dafiah (power...
The global market for herbal products is exploding. The major hindrance in the amalgamation of herbal medicines into modern medical practices is the lack of scientific and clinical data and a better understanding of efficacy and safety of the herbal products. The evaluation or standardization of a crude drug involves Pharmacognostic methods such as organological, physicochemical, phytochemical and...
The present investigation was designed to prepare immediate release tablets of gliclazide with the ultimate aim of reducing the time needed to obtain the peak plasma concentration. Gliclazide immediate release tablets were prepared by using superdisintegrants namely- sodium starch glycolate and croscar-mellose sodium. The prepared tablets were evaluated for weight variation, hardness, friability, ...
PHYTOCHEMICAL SCREENING OF AQUEOUS AND ETHANOL EXTRACTS OF SOME MEDICINAL PLANTS AND IN -VITRO STUDY OF INHIBITION OF α- AMYLASE
In the present study we screened four medicinal plants for the α-amylase inhibitory activity of each extracts phytochemicals, and it was determined based on the colorimetric assay using acarbose as a reference compound. The aqueous and ethanol extracts of the medicinal plants viz. Enicostemma littorale, Achyranthes aspera, Abutilon indicium, and Tridax procumbens were shown moderate α-amylase in...
Vitamin C, also known as ascorbic acid, is a water-soluble antioxidant vitamin having important nutritional and health benefits. Adequate consumption of fruits, vegetables and their juices with high vitamin C content and antioxidant capacity result in improved health, reduced risk of chronic diseases, optimal nutrition and general well-being. Thus, it is essential that vitamin C content in food it...
Aim: The objective of this study was to evaluate the effect of Commiphora mukul on psoriasis. Materials and Methods: Six female Balb/C mice per group of which, the first three groups served as untreated, disease controls and standard (0.1% dexamethasone) respectively. Animals of groups 4, 5 and 6 were applied 0.5, 1 and 2% of the C. mukul extract on both the ears, respectively. Dermatitis was indu...
ASSESSMENT OF ANTIOXIDANT, ANTIBACTERIAL AND ANTHELMINTIC ACTIVITIES OF ETHANOL EXTRACT OF LEAVES OF CROTALARIA PALLIDA (AITON)
The ethanol leaves extract of Crotalaria pallida (Aiton) was evaluated to investigate the Phytochemical nature and some selected pharmacological activities. The plant extract indicated the presence of combined reducing sugar, tannins, flavonoids, glycosides, alkaloids and steroids. The extract showed free radical scavenging activity with an IC50 value of 37.60 µg/ml, and standard ascorbic acid sh...