Posted by admin on Jan 28, 2017 in |
A study was conducted to assess root, leaves and flowers extracts of Cichorium intybus for their antimicrobial activities (against four bacterial and fungal strains), antioxidants activities (DPPH, ABTS H2O2 and reducing power assays) and cytotoxicities assays. The results indicate remarkable inhibition of plant extracts for the growth of all bacterial and fungal strains as well as appropriate MIC values were observed as compared to standard antibiotics used. The activities of these extracts against four assays like DPPH, H2O2, ABTS, and reducing powder was promising. Whereas the cytotoxic activity of extracts study against brine shrimp was reliable. The phytochemical analysis of the various parts of Cichorium intybus revealed that activities of these extracts might be due to the presence of various secondary metabolites like phenolics and flavonoids those were analyzed with higher quantities from these extracts. Therefore such a study could be useful for the development of new pharmaceuticals that could lead such compounds for the preparation of new medicines required for human and animals...
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Posted by admin on Jan 28, 2017 in |
Hyperlipidemia is the most prominent risk factor in coronary heart disease. The present study was designed to investigate the anti-hyperlipidemic activity of Amorphophallus paeoniifolius Tuber in Triton WR-1339 induced hyperlipidemic rats. Amorphophallus paeoniifolius extract was administered at a different dose of 250mg/kg, 500mg/kg (p.o) daily for 7 days to hyperlipidemic rats. Gemfibrozil is used as a reference standard. The statistical analysis was performed by using one way ANOVA followed by the Dunnet’s multiple comparison tests. This is to highlight the presence of the different secondary metabolites, extract by solvents (ethanol) and analyze the content of total phenols from the tuber by the visible UV spectrophotometry method. The results obtained indicate that the tuber of Amorphophallus paeoniifolius contains high concentrations of total phenols (respectively 79, 35 mg GAE/gDM). These polyphenols possess a strong anti-hyperlipidemic activity. Amorphophallus paeoniifolius showed a significant decrease in the levels of serum cholesterol, triglycerides, LDL (low-density lipoprotein), VLDL (very low-density lipoprotein) and the significant increase in the level of serum HDL (high-density lipoprotein) at the dose...
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Posted by admin on Jan 28, 2017 in |
Extracts from leaves, stems and flower buds of Myrciaria glazioviana were analyzed for their antioxidant and anticholinesterase activity. The methanolic extracts showed the best results in reducing power (623.52 – 806.15 mg AA/g of extract), DPPH radical scavenging (IC50 = 9.77 – 14.06 µg/mL) and lipid peroxidation inhibition activity (21.30 – 66.80%). These data were correlated to the total phenolic content (270.19 – 351.01 mg GA/g of extract). The dichloromethane extract of leaves exhibited a higher anti-cholinesterase potential (IC50 = 249.25 µg/mL). Furthermore, the chemical composition of the essential oils from leaves collected in all seasons of the year was analyzed by GC-MS and GC-FID. Only sesquiterpenes were identified in all essential oils, and non-functionalized sesquiterpenes comprised the major fractions (from 66.8 to 79.3%). An increase in non-functionalized compounds was observed in the warmer seasons. Germacrene B was the major compound in all seasons (from 26.8 to 30.1%). In winter and autumn, high contents of germacrene D (10.2 and 10.0%, respectively) and α-cadinol (12.1 and 12.0%, respectively) were identified;...
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Posted by admin on Jan 28, 2017 in |
Thepesia populnea Linn. (Family- Malvaceae) is one of the important drugs used in Herbal medicines. It is known by the name Paras-pipal. It is often cultivated for ornament and shade, and it blooms throughout the year in the tropics. Various parts of this plant are found to possess useful medicinal properties, such as antifertility, antibacterial, anti-inflammatory, antioxidant, purgative, and hepatoprotective activities. The yellow juice of fruits is employed in treating certain hepatic diseases. A decoction of the bark is given internally in the diseases of the skin and that of the fruits as an antidote for poisoning. The seed possesses purgative properties. The plant is useful in malaria. A wide range of biologically active compounds such as flavonoids, sesquiterpenoids, tannin, saponins, alkanes, essential oil, sugars, fatty acids, and antioxidants are present in the plant. This contribution provides a comprehensive review of its ethnomedicinal uses, chemical constituents and pharmacological profile as a medicinal...
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