Posted by admin on Mar 10, 2017 in |
The toxicity of aqueous extracts of S. siamea leaves, S. latifolius roots collected in Benin and their mixture (1/1, w/w), was evaluated on female non-pregnant rats, Albino wistar genus. They were treated for two weeks, with various extracts administered by the oral way at 2000 mg/kg body weight. The biochemical parameters were determinate, histological analysis of the rats was done, and the urinary concentration of neutral gelatinase-associated lipocalin (NGAL) was measured. The treatment of the rats with different extracts not caused undesirable effects and deaths during the fourteen days of observation. Significant changes are relative of a histological aspect of hepatocyte and renal cortex as well as significant increases in the activity of enzyme serum alanine aminotransferases (ALT) and aspartate aminotransferases (AST). The aqueous extracts at 2000 mg/kg were disrupted some biochemical parameters. These changes were confirmed by the rate raised from NGAL noted in the urine of the treated...
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Posted by admin on Mar 10, 2017 in |
The synthetic indicators are used in acid-base titration for determination of endpoint. A part of its application, the synthetic indicators has several limitations such as toxic, costly, corrosive, etc. Thus, herbal indicators are the choice of today for acid-base titrations. The natural indicator is easy to extract as well as easily available. Promising results were obtained when it was compared against standard synthetic indicators. Titration shows a sharp color change at the equivalence point. The equivalence points obtained from the various part of the plant coincide with the equivalence points obtained by the standard indicators. These natural indicators are found to be very useful, economical, accurate and straightforward for the said titration. In this review, we mentioned the importance of some herbal indicators as per their finding reported by the earlier...
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Posted by admin on Mar 10, 2017 in |
Diabetes is an endocrine disorder, and it is due to a deficiency in secretion or action of insulin. The increased prevalence of diabetes in recent decades has made it to severe risk for public health. Human always has great consideration to plants for treatment of illnesses, especially diabetes and it is probably due to common ingredients with mammalian cells such as inositol, especially isomer of D-chiro-inositol, which plays a vital role in the signaling pathway of insulin, and its lack in the structure of inositol phosphoglycan leads to insulin resistance. Therefore, the possession of an inexpensive and available source of this ingredient is essential for patients suffering from diabetes. In the current study, we reviewed the effects of D-chiro-inositol and its derivatives and herbs with them on...
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Posted by admin on Jan 28, 2017 in |
Loganin is an iridoid glycoside, a key phytoconstituent in Strychnos plants having a crucial role in the biosynthesis of indole, monoterpene alkaloids and other natural products. It is a bitter iridoid glycoside with numerous activities like anti-inflammatory, anti-oxidant, glucose-lowering and anti-diabetic nephropathy activities. The objective of this study was to develop a simple method for isolation of loganin from fruit pulp of Nux vomica and quantify by HPLC. The isolated compound was characterized by TLC, UV, IR, MS, and NMR spectral analysis and purity were confirmed by HPLC analysis. Quantification of loganin was done from fruit, seeds and pulp extract using HPLC. A simple solvent partitioning method was used for the extraction and isolation process. This isolation method developed involved easy solvent-solvent extraction technique followed by recrystallization to purify the...
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Posted by admin on Jan 28, 2017 in |
As per the appeal issued by World Health Organization (WHO) “save plants to save lives,” there is the need for a global movement for the conservation of medicinal plants and the revitalization of the native health traditions of local communities. Such health traditions based on medicinal plants are the result of centuries of observation, selection, and experimentation. They thus constitute an accumulated pool of medical wisdom, based on the dictum “an ounce of practice is worth tons of theory.” Unfortunately, such invaluable knowledge and experience are increasingly coming under the category of ‘dying wisdom.’ Throughout human history people have relied on natural products and plants, in particular, to promote and maintain good health and to fight sickness, pain, and disease. The past 200 years have witnessed not only an acceleration in the rate of extinction of plant and animal species but also the erosion of traditional knowledge related to the medicinal properties and uses of the plant and other natural products. India also had a rich tradition for primary...
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