Posted by admin on Aug 31, 2026 in |
The present study evaluated the phytochemical composition and antifungal activity of ethanolic extracts of five medicinal plants: Azadirachta indica (Neem), Ocimum sanctum (Tulsi), Allium sativum (Garlic), Curcuma longa (Turmeric), and Syzygium aromaticum (Clove). Preliminary phytochemical screening revealed the presence of alkaloids, flavonoids, tannins, glycosides, terpenoids, steroids, saponins, and phenolic compounds, with flavonoids and phenolics being the predominant constituents. Antifungal activity was assessed against Candida albicans and Aspergillus niger using the agar well diffusion method. Garlic extract exhibited the highest antifungal activity among the plant extracts, followed by clove and neem, while tulsi showed the lowest activity. Fluconazole demonstrated the greatest inhibition against both fungal strains. The findings support the traditional use of these medicinal plants and suggest that garlic and clove possess promising potential as natural antifungal agents for future therapeutic...
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Posted by admin on Aug 31, 2026 in |
Talisadi Churna is a classical Ayurvedic polyherbal formulation traditionally used in cough, bronchitis, fever, dyspepsia, anaemia and cardiac disorders. The present study was carried out for pharmacognostical, physicochemical and phytochemical evaluation of standard laboratory-prepared and marketed formulations in accordance with WHO guidelines. Diagnostic microscopical features of each crude drug such as lignified fibres, stone cells, starch grains, oleo-resinous parenchyma, silicate crystals and epidermal characters were confirmed in all the formulations, ensuring its identity and authenticity. Phytochemical screening detected alkaloids, flavonoids, phenolics, tannins, carbohydrates, steroids and triterpenoids. Comparative TLC fingerprinting confirmed the presence of all crude drugs in prepared and marketed formulations. HPTLC quantification using piperine as a marker revealed highest content in P. nigrum (4.86%w/w), followed by P. longum (4.809% w/w). Among formulations, laboratory prepared contained 4.88% w/w, with comparatively lower amounts in marketed formulations. The findings provide a comprehensive standardization profile for Talisadi Churna, ensuring quality of both laboratory-prepared and marketed...
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Posted by admin on Aug 31, 2026 in |
Disorders related to female hormonal imbalance can profoundly and permanently affect quality of life. This study aimed to evaluate the estrogenic effects of an aqueous extract of Ricinodendron heudelotii almonds in ovariectomized rats. The seeds, harvested in Andé (Ivory Coast), were dried, ground, and then extracted with distilled water. A phytochemical screening was conducted to identify the main groups of secondary metabolites present in the extract. Acute toxicity was evaluated in six Swiss mice in accordance with OECD Guideline 423. Estrogenic activity was studied in ovariectomized Wistar rats using the OECD 440 uterine trophism bioassay. The animals were divided into four groups: control, ethinyl estradiol (0.02 mg/kg), 100 mg/kg of extract, and 300 mg/kg of extract. The treatments were administered orally daily for seven days. Body weight, as well as the relative weights of the uterus, cervix, and adrenal glands, were assessed. Vaginal smears were also collected to analyze cytological changes in the vaginal epithelium. Phytochemical analysis revealed the presence of sterols, polyterpenes, and alkaloids. No deaths or obvious...
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Posted by admin on Aug 31, 2026 in |
Herbal medicine and their application have always been the basis forman`s curiosity from the time immemorial. Averrhoa carambola is one of the best Indian cooling medicine. It is believed to be responsible for its sweet or sour taste, of which most of the members are traditional it reported remedies to disease in rural India. However, proper justification and validation of their traditional practice are lacking. Averrhoa carambola traditionally known as “kamrakh” and commonly known as star fruit because of its peculiar shape. It was widely in Ayurveda preparations of its fruits and leaves are used to pacify impaired kapha, pitta, skin diseases, pruritis, worm infestations, diarrhea, vomiting, hemorrhoids, intermittent fever, over-perspiration and general debility. The medicinal properties of Averhoa carambola includes anti-inflammatory, analgesic, hypotensive, anthelmintic, antioxidant, anti-ulcer, hypocholesterolemic, hypolipidimic, antimicrobial and antitumor activities. Hence we in tented to explore a comprehensive account of pharmacognostical and phytochemical updated...
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Posted by admin on Aug 31, 2026 in |
Mirabilis jalapa L., commonly known as the Four O’ Clock plant, is a perennial herb belonging to the family Nyctaginaceae. Besides its ornamental importance, the plant has been extensively utilized in traditional medicine for the treatment of inflammation, infections, wounds, diabetes, and various other ailments. The present review summarizes the botanical characteristics, taxonomy, geographical distribution, traditional uses, phytochemical constituents, and pharmacological activities of M. jalapa. Phytochemical investigations have revealed the presence of diverse bioactive compounds, including flavonoids, alkaloids, triterpenes, sterols, glycosides, proteins, peptides, and betalain pigments distributed throughout different plant parts. Experimental studies have demonstrated a wide range of biological activities such as antibacterial, antioxidant, anti-inflammatory, antidiabetic, antiviral, antiasthmatic, antinociceptive, wound-healing, antispasmodic, anticancer, antifungal, anthelmintic, and hepatoprotective effects. These pharmacological properties support many of its traditional medicinal applications. The accumulated evidence suggests that M. jalapa represents a valuable source of natural therapeutic agents and warrants further investigations to isolate active constituents, elucidate mechanisms of action, and validate its efficacy and safety through clinical...
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